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The map label for this gene is 220933105

Identifier: 220933105

GI number: 220933105

Start: 2481229

End: 2482302

Strand: Reverse

Name: 220933105

Synonym: Hore_22730

Alternate gene names: NA

Gene position: 2482302-2481229 (Counterclockwise)

Preceding gene: 220933106

Following gene: 220933104

Centisome position: 96.28

GC content: 43.85

Gene sequence:

>1074_bases
TTGTTAATAGATTTAAATAATATTGAAAAGGTTAAGGAGATTGATAGCCAGAAGGCCATTGAAACCACGGAAAATTATGA
CAGTCAGTTTCAGGAAGGTTTGAAACTCGGACAATCCATTGAGATTGAAGAACTACCGGACCGGATTGATAATATAATCC
TGCTGGGGACCGGTGGGGGGTCAGCAATCACCGGGGGGCTTTTACAGTCCTACCTGTTTGATGAATTACCTGTTCCCCTG
TATATAAATCAGGGTTATAATATTCCGGCCTGGGTCGATGAGAATACCCTGGTTTTAGTTGTATCCCATTCTGGTAATAC
TGAAGAGATTGTTAATTCCTTCAAACAGGCGGAACAGAGGGGAGCCTGTATCTTTATTCTGACCTCAGGGGGGATCCTGG
GTGAAAAGGCCCGGGAGCAGGGAATACCCCATCTAATTGTACCCCGGGATATCGGCCATCCCCGCCGGGACCTTGGTTAT
ATCTTTATCCCTTTACTTGCTTTGCTTAACAAACTGGGGTTAATTGAAGATAAAACCGGTGAGGTACTGGATTTGATAGA
GCTATTCGGGGAATTAAAAAACCGTTACCGGCTTAAAACCCCCCTTGAGAAAAATCCGGCCAAACAACTGGCTGTTGATC
TGGACAACTACATTCCGCTCATCTATGGTTCCCTGGATTATTATGATGTGGTAGCCTGGCGGTGGAAGAACCAGTTTGGA
GAAAATGGTAAAAAGCTGGCCTTTTATAACGTTATCCCCAACCTGCACCATGATGAGGCCGTGGGATGGGAGATGGAAAA
AGAGGTACTGGAGAGGTTTTACCTGGTGGTTTTAAGGGATTCAGAACTTGACCTGGATAATATTAAAAAACGCAAGGATG
TTACCGTTGAAATCCTCAGAGAAAGGATCGGCAAGGTTATCGAGGTTTATGCTGAAGGTCATACCAGGCTGGCCAGGATG
TTTTCTTTAATCTACCTGGGAGATTTTGTTACCATTTATCATGCAATTGCCAGGGGGATAGACCCGACACCGGTAAATAT
AATAGATTATTTTAAAAAGAAAATGATGGAGTGA

Upstream 100 bases:

>100_bases
TAAATAGAGTATCGATAGTTAATTTTCAGGTGTGGACTTTAAACCGGGGGGTTTTTTGCCGGAGATATCATGCCGGAATC
CTGGAGAGGGGGTAATGTAG

Downstream 100 bases:

>100_bases
TTTTCATGGTAGTAACTGTTACCCTTAATACTTCAGTAGATAAGGCCTATATACTCAACCAGATGGAAACAGGTGGGGTA
AACAGGGTCAAAGAGACCCG

Product: bifunctional phosphoglucose/phosphomannose isomerase

Products: NA

Alternate protein names: Glucose-6-phosphate isomerase; GPI; Mannose-6-phosphate isomerase; Phosphoglucose isomerase; PGI; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLIDLNNIEKVKEIDSQKAIETTENYDSQFQEGLKLGQSIEIEELPDRIDNIILLGTGGGSAITGGLLQSYLFDELPVPL
YINQGYNIPAWVDENTLVLVVSHSGNTEEIVNSFKQAEQRGACIFILTSGGILGEKAREQGIPHLIVPRDIGHPRRDLGY
IFIPLLALLNKLGLIEDKTGEVLDLIELFGELKNRYRLKTPLEKNPAKQLAVDLDNYIPLIYGSLDYYDVVAWRWKNQFG
ENGKKLAFYNVIPNLHHDEAVGWEMEKEVLERFYLVVLRDSELDLDNIKKRKDVTVEILRERIGKVIEVYAEGHTRLARM
FSLIYLGDFVTIYHAIARGIDPTPVNIIDYFKKKMME

Sequences:

>Translated_357_residues
MLIDLNNIEKVKEIDSQKAIETTENYDSQFQEGLKLGQSIEIEELPDRIDNIILLGTGGGSAITGGLLQSYLFDELPVPL
YINQGYNIPAWVDENTLVLVVSHSGNTEEIVNSFKQAEQRGACIFILTSGGILGEKAREQGIPHLIVPRDIGHPRRDLGY
IFIPLLALLNKLGLIEDKTGEVLDLIELFGELKNRYRLKTPLEKNPAKQLAVDLDNYIPLIYGSLDYYDVVAWRWKNQFG
ENGKKLAFYNVIPNLHHDEAVGWEMEKEVLERFYLVVLRDSELDLDNIKKRKDVTVEILRERIGKVIEVYAEGHTRLARM
FSLIYLGDFVTIYHAIARGIDPTPVNIIDYFKKKMME
>Mature_357_residues
MLIDLNNIEKVKEIDSQKAIETTENYDSQFQEGLKLGQSIEIEELPDRIDNIILLGTGGGSAITGGLLQSYLFDELPVPL
YINQGYNIPAWVDENTLVLVVSHSGNTEEIVNSFKQAEQRGACIFILTSGGILGEKAREQGIPHLIVPRDIGHPRRDLGY
IFIPLLALLNKLGLIEDKTGEVLDLIELFGELKNRYRLKTPLEKNPAKQLAVDLDNYIPLIYGSLDYYDVVAWRWKNQFG
ENGKKLAFYNVIPNLHHDEAVGWEMEKEVLERFYLVVLRDSELDLDNIKKRKDVTVEILRERIGKVIEVYAEGHTRLARM
FSLIYLGDFVTIYHAIARGIDPTPVNIIDYFKKKMME

Specific function: Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency [H]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011857
- InterPro:   IPR019490
- InterPro:   IPR001347 [H]

Pfam domain/function: PF10432 bact-PGI_C; PF01380 SIS [H]

EC number: =5.3.1.9; =5.3.1.8 [H]

Molecular weight: Translated: 40718; Mature: 40718

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDLNNIEKVKEIDSQKAIETTENYDSQFQEGLKLGQSIEIEELPDRIDNIILLGTGGG
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCC
SAITGGLLQSYLFDELPVPLYINQGYNIPAWVDENTLVLVVSHSGNTEEIVNSFKQAEQR
HHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHC
GACIFILTSGGILGEKAREQGIPHLIVPRDIGHPRRDLGYIFIPLLALLNKLGLIEDKTG
CCEEEEEECCCCCCCHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
EVLDLIELFGELKNRYRLKTPLEKNPAKQLAVDLDNYIPLIYGSLDYYDVVAWRWKNQFG
HHHHHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHC
ENGKKLAFYNVIPNLHHDEAVGWEMEKEVLERFYLVVLRDSELDLDNIKKRKDVTVEILR
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHHHH
ERIGKVIEVYAEGHTRLARMFSLIYLGDFVTIYHAIARGIDPTPVNIIDYFKKKMME
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLIDLNNIEKVKEIDSQKAIETTENYDSQFQEGLKLGQSIEIEELPDRIDNIILLGTGGG
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCC
SAITGGLLQSYLFDELPVPLYINQGYNIPAWVDENTLVLVVSHSGNTEEIVNSFKQAEQR
HHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHC
GACIFILTSGGILGEKAREQGIPHLIVPRDIGHPRRDLGYIFIPLLALLNKLGLIEDKTG
CCEEEEEECCCCCCCHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
EVLDLIELFGELKNRYRLKTPLEKNPAKQLAVDLDNYIPLIYGSLDYYDVVAWRWKNQFG
HHHHHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHC
ENGKKLAFYNVIPNLHHDEAVGWEMEKEVLERFYLVVLRDSELDLDNIKKRKDVTVEILR
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHHHH
ERIGKVIEVYAEGHTRLARMFSLIYLGDFVTIYHAIARGIDPTPVNIIDYFKKKMME
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA