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The map label for this gene is cheA [H]

Identifier: 220933093

GI number: 220933093

Start: 2465192

End: 2467291

Strand: Reverse

Name: cheA [H]

Synonym: Hore_22610

Alternate gene names: 220933093

Gene position: 2467291-2465192 (Counterclockwise)

Preceding gene: 220933094

Following gene: 220933092

Centisome position: 95.7

GC content: 38.81

Gene sequence:

>2100_bases
ATGACTGAAGGAGACCTGCTTAATACCTTTATTGAAGAGGCAAAGGAATTACTGGATAAGATGGTAGTAGACCTGCTTGA
GCTGGAGGCAAAACCAGGTGATATGGATTTGATTAATAACATTTTCAGGGGGATGCATACTCTGAAAGGAAGTGCCAGTC
TAACAGGCCTTAACGATATTGCTAATTTTGTTCATCATTCTGAGGATTTACTGGACCAGGTCAGAAGAGGATGTATTACA
GTAAATGATAAGGTTATTAATTTATTACTCACATGTACTGACCTGATTGGAGAAATGGTTGAAGCGCTAGGTAATGATGA
TGTGCAGGTTAAAAATGAGAAAGTTGAGTCTATTATATGGGAAATTAAAAAGTTGTTGAAGGATCAAACAGAACATACTC
CTTCTGAGGAAGGAAGTCTTGGAGATAATCTACATAATTTTGGTACAGGGGAAAGATGTTACCGTATTAAACTCGATTTC
AATCCCAATTTATTTGAAACAGGTACAGACCCCTTGATGCTTGTCAGGGAACTAAGGGAATTTAGTGACATATTGATGGT
GGCAGTCAATTATACCAGGGTACCTGACTTATACAACCTTGATCCTGAATTATGTTATCTTACATTAACTATCTTAATTA
AAACCGGGGTAGGAATTGATAGGATAAAGGATGTCTTTATTTTTGTTCAGGTTGATAATAAGGTAGAAATTGAAGATATC
ACAGAAAATTTCTCTGACAATATTGACATTTCCCTGTCAGATAAAAAGACAGGTGAAATACTGGTTGAGAGAGGGATTGT
TGAAGAAGAAGATATCACACAGGCCCTTGCAAGGCAAAAAAAGATTGGAGAAATATTAACTGAGGAAGGAAAGGTAAGCA
GGGAACAGGTTCAGAGGGTTGTTTATGACCAGCACAAAAGTCGGGCGGTAAAGGAAAAGAGTACTATTAAGGTAGATACG
CATAAACTGGAGTCCCTAATGAATTCTATGGCTGAACTGGTAATTGCCCAGGCCAAGGTCAGGGAATTAGTTATTCATAG
AACCGACAGGTCTGAAAATGAGATAATGACTGCCTTAAATTCGGTTGATAAAAGGATACGTAACCTGCAGGAAGATATTA
TGAAAGTAAGAATGGTTCCCATTGGTAATACATTTCTTAGGTTCAAAAGGCTGGTCAGGGACCTATCACGAGAACAGGGA
AAAGAAATCAATCTGGAAATAAGGGGTAAAGAGACTGAACTGGATAAAATTGTTATTGAACGAATCTATGATCCTTTAAA
ACACATGATCAGGAATTCAGTTGACCACGGAATAGAACCACCTGAAGAAAGAGAAGCATTGGGAAAAAACAGGGTTGGTA
CGATATCATTGAATTCTTATCATCAGGAAGGGAATATCATCATTGAGGTTGCCGATGACGGTAGGGGTCTGGATAAAGAG
AAAATACTGGATAAAGCTATCAACCGGGGGGTAGTCGATGAAGACCAGGAACTGACAGAACAGGGAATCTACCGGCTAAT
ATTCGAACCAGGTCTTTCCACAAGTGAAGAAGTTACAGAGACTTCAGGACGCGGGGTAGGAATGGATGTAGTCAGGAATA
ATATTGAACAGCTTAGAGGTACTATTAATATATTTAGCAACCCGGGCGAAGGGACAAGGTTTAAAATAAAACTCCCGCTG
ACACTGGCAATAATTGATGGAATGAATGTTAAAGTCGGAGATGAACAGTTTATTATACCGTTGAATTCTATAGTTGAGTT
TATCAGGCCACTACCTGAGCATATAAAAACAGTTAATGGCAAGGGAGAGGTAGTTAAAGTCAGGGACGAATATATAACTT
TGAGCAGGCTCTATAAATTGTTTAATTTAAAGGGCAGTAAAACTGACCCAACCGAGGGTATACTGGTTATCTTACAGGAT
GAAAACCGCAAACTCTGTTTGCTGGTCGATGAAATTGTTGGCCAGCAACAGGCAGTGGTGAAAAGTATGGAAGATAATTA
TACATTTATTGACGGAATTGCAGGAGCAACTATTATGGGTGACGGCAGGGTTGCCATGATACTGGATGTATCTACTATTA
TCAGGATGGCTGTTAATTAA

Upstream 100 bases:

>100_bases
AAAGAAGCCGGGGCGGCAGGGTGGCTTGTTAAACCATTTAAACCTGAACAGCTAATTAGTGTTGCCAGAAAGTTTATTAA
ATAGAGGGAGGGGGGAATAA

Downstream 100 bases:

>100_bases
ATGAAGGGGGGGACTTATTTATGAGTGGGGAAGCAAGGGGAAAGCAGGATAATACACTGGATATACTGAACCAGCAGTTA
ACCAGTATATCTGCTGAGAA

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MTEGDLLNTFIEEAKELLDKMVVDLLELEAKPGDMDLINNIFRGMHTLKGSASLTGLNDIANFVHHSEDLLDQVRRGCIT
VNDKVINLLLTCTDLIGEMVEALGNDDVQVKNEKVESIIWEIKKLLKDQTEHTPSEEGSLGDNLHNFGTGERCYRIKLDF
NPNLFETGTDPLMLVRELREFSDILMVAVNYTRVPDLYNLDPELCYLTLTILIKTGVGIDRIKDVFIFVQVDNKVEIEDI
TENFSDNIDISLSDKKTGEILVERGIVEEEDITQALARQKKIGEILTEEGKVSREQVQRVVYDQHKSRAVKEKSTIKVDT
HKLESLMNSMAELVIAQAKVRELVIHRTDRSENEIMTALNSVDKRIRNLQEDIMKVRMVPIGNTFLRFKRLVRDLSREQG
KEINLEIRGKETELDKIVIERIYDPLKHMIRNSVDHGIEPPEEREALGKNRVGTISLNSYHQEGNIIIEVADDGRGLDKE
KILDKAINRGVVDEDQELTEQGIYRLIFEPGLSTSEEVTETSGRGVGMDVVRNNIEQLRGTINIFSNPGEGTRFKIKLPL
TLAIIDGMNVKVGDEQFIIPLNSIVEFIRPLPEHIKTVNGKGEVVKVRDEYITLSRLYKLFNLKGSKTDPTEGILVILQD
ENRKLCLLVDEIVGQQQAVVKSMEDNYTFIDGIAGATIMGDGRVAMILDVSTIIRMAVN

Sequences:

>Translated_699_residues
MTEGDLLNTFIEEAKELLDKMVVDLLELEAKPGDMDLINNIFRGMHTLKGSASLTGLNDIANFVHHSEDLLDQVRRGCIT
VNDKVINLLLTCTDLIGEMVEALGNDDVQVKNEKVESIIWEIKKLLKDQTEHTPSEEGSLGDNLHNFGTGERCYRIKLDF
NPNLFETGTDPLMLVRELREFSDILMVAVNYTRVPDLYNLDPELCYLTLTILIKTGVGIDRIKDVFIFVQVDNKVEIEDI
TENFSDNIDISLSDKKTGEILVERGIVEEEDITQALARQKKIGEILTEEGKVSREQVQRVVYDQHKSRAVKEKSTIKVDT
HKLESLMNSMAELVIAQAKVRELVIHRTDRSENEIMTALNSVDKRIRNLQEDIMKVRMVPIGNTFLRFKRLVRDLSREQG
KEINLEIRGKETELDKIVIERIYDPLKHMIRNSVDHGIEPPEEREALGKNRVGTISLNSYHQEGNIIIEVADDGRGLDKE
KILDKAINRGVVDEDQELTEQGIYRLIFEPGLSTSEEVTETSGRGVGMDVVRNNIEQLRGTINIFSNPGEGTRFKIKLPL
TLAIIDGMNVKVGDEQFIIPLNSIVEFIRPLPEHIKTVNGKGEVVKVRDEYITLSRLYKLFNLKGSKTDPTEGILVILQD
ENRKLCLLVDEIVGQQQAVVKSMEDNYTFIDGIAGATIMGDGRVAMILDVSTIIRMAVN
>Mature_698_residues
TEGDLLNTFIEEAKELLDKMVVDLLELEAKPGDMDLINNIFRGMHTLKGSASLTGLNDIANFVHHSEDLLDQVRRGCITV
NDKVINLLLTCTDLIGEMVEALGNDDVQVKNEKVESIIWEIKKLLKDQTEHTPSEEGSLGDNLHNFGTGERCYRIKLDFN
PNLFETGTDPLMLVRELREFSDILMVAVNYTRVPDLYNLDPELCYLTLTILIKTGVGIDRIKDVFIFVQVDNKVEIEDIT
ENFSDNIDISLSDKKTGEILVERGIVEEEDITQALARQKKIGEILTEEGKVSREQVQRVVYDQHKSRAVKEKSTIKVDTH
KLESLMNSMAELVIAQAKVRELVIHRTDRSENEIMTALNSVDKRIRNLQEDIMKVRMVPIGNTFLRFKRLVRDLSREQGK
EINLEIRGKETELDKIVIERIYDPLKHMIRNSVDHGIEPPEEREALGKNRVGTISLNSYHQEGNIIIEVADDGRGLDKEK
ILDKAINRGVVDEDQELTEQGIYRLIFEPGLSTSEEVTETSGRGVGMDVVRNNIEQLRGTINIFSNPGEGTRFKIKLPLT
LAIIDGMNVKVGDEQFIIPLNSIVEFIRPLPEHIKTVNGKGEVVKVRDEYITLSRLYKLFNLKGSKTDPTEGILVILQDE
NRKLCLLVDEIVGQQQAVVKSMEDNYTFIDGIAGATIMGDGRVAMILDVSTIIRMAVN

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=403, Percent_Identity=45.6575682382134, Blast_Score=371, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79056; Mature: 78925

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGDLLNTFIEEAKELLDKMVVDLLELEAKPGDMDLINNIFRGMHTLKGSASLTGLNDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
ANFVHHSEDLLDQVRRGCITVNDKVINLLLTCTDLIGEMVEALGNDDVQVKNEKVESIIW
HHHHHCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
EIKKLLKDQTEHTPSEEGSLGDNLHNFGTGERCYRIKLDFNPNLFETGTDPLMLVRELRE
HHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHH
FSDILMVAVNYTRVPDLYNLDPELCYLTLTILIKTGVGIDRIKDVFIFVQVDNKVEIEDI
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCEEEEEEEECCEEEHHHH
TENFSDNIDISLSDKKTGEILVERGIVEEEDITQALARQKKIGEILTEEGKVSREQVQRV
HHCCCCCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VYDQHKSRAVKEKSTIKVDTHKLESLMNSMAELVIAQAKVRELVIHRTDRSENEIMTALN
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SVDKRIRNLQEDIMKVRMVPIGNTFLRFKRLVRDLSREQGKEINLEIRGKETELDKIVIE
HHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHH
RIYDPLKHMIRNSVDHGIEPPEEREALGKNRVGTISLNSYHQEGNIIIEVADDGRGLDKE
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCEECCCCEEEEECCCCCCCCHH
KILDKAINRGVVDEDQELTEQGIYRLIFEPGLSTSEEVTETSGRGVGMDVVRNNIEQLRG
HHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCC
TINIFSNPGEGTRFKIKLPLTLAIIDGMNVKVGDEQFIIPLNSIVEFIRPLPEHIKTVNG
EEEEECCCCCCCEEEEEECEEEEEECCCCEEECCCEEEEEHHHHHHHHHHHHHHHHCCCC
KGEVVKVRDEYITLSRLYKLFNLKGSKTDPTEGILVILQDENRKLCLLVDEIVGQQQAVV
CCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCHHHHHH
KSMEDNYTFIDGIAGATIMGDGRVAMILDVSTIIRMAVN
HHHCCCCEEEECCCCCEEECCCCEEEEEEHHHHHHHHCC
>Mature Secondary Structure 
TEGDLLNTFIEEAKELLDKMVVDLLELEAKPGDMDLINNIFRGMHTLKGSASLTGLNDI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
ANFVHHSEDLLDQVRRGCITVNDKVINLLLTCTDLIGEMVEALGNDDVQVKNEKVESIIW
HHHHHCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
EIKKLLKDQTEHTPSEEGSLGDNLHNFGTGERCYRIKLDFNPNLFETGTDPLMLVRELRE
HHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHH
FSDILMVAVNYTRVPDLYNLDPELCYLTLTILIKTGVGIDRIKDVFIFVQVDNKVEIEDI
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCEEEEEEEECCEEEHHHH
TENFSDNIDISLSDKKTGEILVERGIVEEEDITQALARQKKIGEILTEEGKVSREQVQRV
HHCCCCCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VYDQHKSRAVKEKSTIKVDTHKLESLMNSMAELVIAQAKVRELVIHRTDRSENEIMTALN
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SVDKRIRNLQEDIMKVRMVPIGNTFLRFKRLVRDLSREQGKEINLEIRGKETELDKIVIE
HHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHH
RIYDPLKHMIRNSVDHGIEPPEEREALGKNRVGTISLNSYHQEGNIIIEVADDGRGLDKE
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCEECCCCEEEEECCCCCCCCHH
KILDKAINRGVVDEDQELTEQGIYRLIFEPGLSTSEEVTETSGRGVGMDVVRNNIEQLRG
HHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCC
TINIFSNPGEGTRFKIKLPLTLAIIDGMNVKVGDEQFIIPLNSIVEFIRPLPEHIKTVNG
EEEEECCCCCCCEEEEEECEEEEEECCCCEEECCCEEEEEHHHHHHHHHHHHHHHHCCCC
KGEVVKVRDEYITLSRLYKLFNLKGSKTDPTEGILVILQDENRKLCLLVDEIVGQQQAVV
CCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCHHHHHH
KSMEDNYTFIDGIAGATIMGDGRVAMILDVSTIIRMAVN
HHHCCCCEEEECCCCCEEECCCCEEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]