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The map label for this gene is phoP [H]

Identifier: 220933094

GI number: 220933094

Start: 2467308

End: 2467682

Strand: Reverse

Name: phoP [H]

Synonym: Hore_22620

Alternate gene names: 220933094

Gene position: 2467682-2467308 (Counterclockwise)

Preceding gene: 220933095

Following gene: 220933093

Centisome position: 95.72

GC content: 40.53

Gene sequence:

>375_bases
TTGGCAAAAAAAATCATGGTTATTGATGATTCTAAAACTGTACGGGCTTCAGTCCGATATGCCCTGGCCAGACACGGCTA
TGAAGTTATTATGGCTGAAGACGGGCAGGAAGGTTTAGATATCCTGAAAGAACAATCCAGAGAAAAACCCGGGATGATTA
TTACTGATGTTAATATGCCCCGGATGGACGGGATAACCTTCATTAAAGAGGTTAAAAAAGAAAAGCAGTTTAAGTTTATT
CCTATTCTTGTCCTGACAACAGAGTCCCAGGAAGAAATGAAGTTAAAGGGAAAAGAAGCCGGGGCGGCAGGGTGGCTTGT
TAAACCATTTAAACCTGAACAGCTAATTAGTGTTGCCAGAAAGTTTATTAAATAG

Upstream 100 bases:

>100_bases
AAGAGTGTTGATCAGTTAACCCTGAAAAATTCTGTAAAACCACTTATTGAGGCCCTTGAACTAGCAGGATTGGACTGGCT
CCTGGATGGGGGTGTTGAGG

Downstream 100 bases:

>100_bases
AGGGAGGGGGGAATAAATGACTGAAGGAGACCTGCTTAATACCTTTATTGAAGAGGCAAAGGAATTACTGGATAAGATGG
TAGTAGACCTGCTTGAGCTG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MAKKIMVIDDSKTVRASVRYALARHGYEVIMAEDGQEGLDILKEQSREKPGMIITDVNMPRMDGITFIKEVKKEKQFKFI
PILVLTTESQEEMKLKGKEAGAAGWLVKPFKPEQLISVARKFIK

Sequences:

>Translated_124_residues
MAKKIMVIDDSKTVRASVRYALARHGYEVIMAEDGQEGLDILKEQSREKPGMIITDVNMPRMDGITFIKEVKKEKQFKFI
PILVLTTESQEEMKLKGKEAGAAGWLVKPFKPEQLISVARKFIK
>Mature_123_residues
AKKIMVIDDSKTVRASVRYALARHGYEVIMAEDGQEGLDILKEQSREKPGMIITDVNMPRMDGITFIKEVKKEKQFKFIP
ILVLTTESQEEMKLKGKEAGAAGWLVKPFKPEQLISVARKFIK

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=34.1880341880342, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1788191, Length=112, Percent_Identity=33.9285714285714, Blast_Score=80, Evalue=3e-17,
Organism=Escherichia coli, GI1786911, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=25.4098360655738, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=29.0598290598291, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=26.890756302521, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1790863, Length=120, Percent_Identity=28.3333333333333, Blast_Score=63, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14111; Mature: 13980

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKIMVIDDSKTVRASVRYALARHGYEVIMAEDGQEGLDILKEQSREKPGMIITDVNMP
CCCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCC
RMDGITFIKEVKKEKQFKFIPILVLTTESQEEMKLKGKEAGAAGWLVKPFKPEQLISVAR
CCCCHHHHHHHHHHCCCEEEEEEEEECCCHHHHHCCCCCCCCCCCEECCCCHHHHHHHHH
KFIK
HHCC
>Mature Secondary Structure 
AKKIMVIDDSKTVRASVRYALARHGYEVIMAEDGQEGLDILKEQSREKPGMIITDVNMP
CCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCC
RMDGITFIKEVKKEKQFKFIPILVLTTESQEEMKLKGKEAGAAGWLVKPFKPEQLISVAR
CCCCHHHHHHHHHHCCCEEEEEEEEECCCHHHHHCCCCCCCCCCCEECCCCHHHHHHHHH
KFIK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]