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The map label for this gene is sdcS [H]

Identifier: 220933064

GI number: 220933064

Start: 2432646

End: 2434025

Strand: Reverse

Name: sdcS [H]

Synonym: Hore_22320

Alternate gene names: 220933064

Gene position: 2434025-2432646 (Counterclockwise)

Preceding gene: 220933065

Following gene: 220933063

Centisome position: 94.41

GC content: 42.97

Gene sequence:

>1380_bases
ATGAGGTTAAAAAGGATAATTGTCGTCTGTGGTCTTATAATAAGTTTGTTTTTATTGTTAATACCGCCACCGGCAGGGCT
TACGGTATCTGGCAAAAATGCCTTTGCCATTTTTATAATCAGTTTAACCCTCTGGGTTACTAACATCATACCCCTTGCTA
TGACCAGCCTTCTGGGTATGGCTTTGATTCCCTTACTCGGGGTTATGGATGTTGAGGAGTCCTTTTCTCTGTTCGGGAAT
AAGGCTATCTTCTTTATCCTGGGGGCCTTAATTCTGGCTGCAGGAATCCAGAAAACAGGCCTCGGGGTCAGGATAGCTTA
CCGGATATTACTTTTTTTTGACGGGAGTGCCAATAATTTAATTGGTGGTATTTTGACAACAGCAGCTCTCCTATCGTGTA
TTATGCCCGAACACGCTGTAGCAGCCCTGTTGTTTCCGATAGTGATTCAGATATCACGCAGTCTAAATTTAAAACCGATG
GAAAGTCAACTGGGTAAGGCCCTGTTCCTGTCCCTGGCCTGGGGAGCTGTTATCGGGGGGATAACTACCTATTTAGGTGG
AGCCCGGAATTTGCTGGCGGTAGATATTCTCCAGAAAAATTATCACATTTCCATAGGTTTTGTTAACTGGATTCTTATGG
CCCTTCCCATTCCCATTATAATTTTAATACTGGCCTATTTTACAATTACATATTTCTTTAAACCGGAAATAACGGACTCA
GTTGAGGCTAAAAAGAAACTGGAAAAAATAATGGGTAATCAGGGCCAACTCAGTAAATCGGAGAAAAAACTGATTGCTGT
CCTTATAATGGTTATTCTGATGTGGCTTTTACTATCCTCCAGGGTTGACATTGCTATTACGGCCCTTCTGGGGGGAGTGG
CTATTTTCGTCCTTGATATCGTTAAGTGGAAGGACATTGTAGATTATGTAAACTGGGGAGTAATCTTTATGTACGGAGGG
GCTATTGTTGTAGCCAGCTCCCTGAGTATTACCGGTGCTGCTGCCTGGCTCTCCAGTACGATTTTCTCCAGTATTTCTGT
AAGTCCCTTTATCTTTATTGCTGTTATTACCCTGGTTACTAAACTTTTGACCGAAGGGATCAGTAATGTGGCTGCTGTGG
CCATCATACTTCCCCTTGCCTTTAGCTGGGGTGAAATAAGTCAGATAAACCCGATAGCAACTACACTGGCTGTTGCCCTA
TCAGGAGGTTTAGCCTTCTGTTTGCCCATGGGGACTCCTCCCAATGCCATTGCGTTTTCGGCTGGTTATTACAGGATAAG
TGATGTCCTGAAGGTTGGGGTCATTTTGAACATAATTTCCTGGGTAGTGGTATTGTTAATCAGTAAATTTTACTGGCCAC
TCCTCGGTATAAATTTATAA

Upstream 100 bases:

>100_bases
GAGGAAATATTTAGTAGAGAGGATTTGATAAAAGAGGAAATTAATCTTATAAAACAGCGTTTGAAGAGTTTAGGATACCT
GGAATAAAGAGGGGTAAAAA

Downstream 100 bases:

>100_bases
CATTAGCATTTCAGGACTTTAACCATTTCAGGAGTAGTTGTGCTGGCAGGTAATAAAAGAATAATTTCCCAGGGTTGGTA
GTTAAGGGCTTAAACCCTGA

Product: anion transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRLKRIIVVCGLIISLFLLLIPPPAGLTVSGKNAFAIFIISLTLWVTNIIPLAMTSLLGMALIPLLGVMDVEESFSLFGN
KAIFFILGALILAAGIQKTGLGVRIAYRILLFFDGSANNLIGGILTTAALLSCIMPEHAVAALLFPIVIQISRSLNLKPM
ESQLGKALFLSLAWGAVIGGITTYLGGARNLLAVDILQKNYHISIGFVNWILMALPIPIIILILAYFTITYFFKPEITDS
VEAKKKLEKIMGNQGQLSKSEKKLIAVLIMVILMWLLLSSRVDIAITALLGGVAIFVLDIVKWKDIVDYVNWGVIFMYGG
AIVVASSLSITGAAAWLSSTIFSSISVSPFIFIAVITLVTKLLTEGISNVAAVAIILPLAFSWGEISQINPIATTLAVAL
SGGLAFCLPMGTPPNAIAFSAGYYRISDVLKVGVILNIISWVVVLLISKFYWPLLGINL

Sequences:

>Translated_459_residues
MRLKRIIVVCGLIISLFLLLIPPPAGLTVSGKNAFAIFIISLTLWVTNIIPLAMTSLLGMALIPLLGVMDVEESFSLFGN
KAIFFILGALILAAGIQKTGLGVRIAYRILLFFDGSANNLIGGILTTAALLSCIMPEHAVAALLFPIVIQISRSLNLKPM
ESQLGKALFLSLAWGAVIGGITTYLGGARNLLAVDILQKNYHISIGFVNWILMALPIPIIILILAYFTITYFFKPEITDS
VEAKKKLEKIMGNQGQLSKSEKKLIAVLIMVILMWLLLSSRVDIAITALLGGVAIFVLDIVKWKDIVDYVNWGVIFMYGG
AIVVASSLSITGAAAWLSSTIFSSISVSPFIFIAVITLVTKLLTEGISNVAAVAIILPLAFSWGEISQINPIATTLAVAL
SGGLAFCLPMGTPPNAIAFSAGYYRISDVLKVGVILNIISWVVVLLISKFYWPLLGINL
>Mature_459_residues
MRLKRIIVVCGLIISLFLLLIPPPAGLTVSGKNAFAIFIISLTLWVTNIIPLAMTSLLGMALIPLLGVMDVEESFSLFGN
KAIFFILGALILAAGIQKTGLGVRIAYRILLFFDGSANNLIGGILTTAALLSCIMPEHAVAALLFPIVIQISRSLNLKPM
ESQLGKALFLSLAWGAVIGGITTYLGGARNLLAVDILQKNYHISIGFVNWILMALPIPIIILILAYFTITYFFKPEITDS
VEAKKKLEKIMGNQGQLSKSEKKLIAVLIMVILMWLLLSSRVDIAITALLGGVAIFVLDIVKWKDIVDYVNWGVIFMYGG
AIVVASSLSITGAAAWLSSTIFSSISVSPFIFIAVITLVTKLLTEGISNVAAVAIILPLAFSWGEISQINPIATTLAVAL
SGGLAFCLPMGTPPNAIAFSAGYYRISDVLKVGVILNIISWVVVLLISKFYWPLLGINL

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=507, Percent_Identity=24.65483234714, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI31795546, Length=364, Percent_Identity=24.1758241758242, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI31377715, Length=558, Percent_Identity=22.7598566308244, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI301069349, Length=478, Percent_Identity=22.8033472803347, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI58761541, Length=515, Percent_Identity=22.3300970873786, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI19923838, Length=326, Percent_Identity=25.1533742331288, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI301069353, Length=335, Percent_Identity=23.5820895522388, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI219802232, Length=440, Percent_Identity=22.0454545454545, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4506979, Length=149, Percent_Identity=31.5436241610738, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI225637552, Length=162, Percent_Identity=30.8641975308642, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI225637549, Length=162, Percent_Identity=30.8641975308642, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI301069346, Length=149, Percent_Identity=28.8590604026846, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1786829, Length=469, Percent_Identity=24.5202558635394, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789444, Length=465, Percent_Identity=23.4408602150538, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786986, Length=464, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988385, Length=457, Percent_Identity=26.2582056892779, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32565804, Length=443, Percent_Identity=25.9593679458239, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17551790, Length=501, Percent_Identity=22.5548902195609, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI32564681, Length=513, Percent_Identity=22.0272904483431, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71989118, Length=539, Percent_Identity=22.6345083487941, Blast_Score=119, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6324340, Length=371, Percent_Identity=23.4501347708895, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362116, Length=448, Percent_Identity=23.6607142857143, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281362114, Length=448, Percent_Identity=23.6607142857143, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281362112, Length=448, Percent_Identity=23.6607142857143, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281366409, Length=469, Percent_Identity=21.3219616204691, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17737623, Length=469, Percent_Identity=21.3219616204691, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24666468, Length=469, Percent_Identity=21.3219616204691, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45551633, Length=469, Percent_Identity=21.3219616204691, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78706796, Length=485, Percent_Identity=22.8865979381443, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI78706798, Length=485, Percent_Identity=22.8865979381443, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 49308; Mature: 49308

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKRIIVVCGLIISLFLLLIPPPAGLTVSGKNAFAIFIISLTLWVTNIIPLAMTSLLGM
CCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIPLLGVMDVEESFSLFGNKAIFFILGALILAAGIQKTGLGVRIAYRILLFFDGSANNL
HHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCHHCCCHHEEEEEEEEEECCCCCHH
IGGILTTAALLSCIMPEHAVAALLFPIVIQISRSLNLKPMESQLGKALFLSLAWGAVIGG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ITTYLGGARNLLAVDILQKNYHISIGFVNWILMALPIPIIILILAYFTITYFFKPEITDS
HHHHHCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
VEAKKKLEKIMGNQGQLSKSEKKLIAVLIMVILMWLLLSSRVDIAITALLGGVAIFVLDI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VKWKDIVDYVNWGVIFMYGGAIVVASSLSITGAAAWLSSTIFSSISVSPFIFIAVITLVT
HHHHHHHHHHCCCCEEEECCHHEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KLLTEGISNVAAVAIILPLAFSWGEISQINPIATTLAVALSGGLAFCLPMGTPPNAIAFS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEC
AGYYRISDVLKVGVILNIISWVVVLLISKFYWPLLGINL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLKRIIVVCGLIISLFLLLIPPPAGLTVSGKNAFAIFIISLTLWVTNIIPLAMTSLLGM
CCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIPLLGVMDVEESFSLFGNKAIFFILGALILAAGIQKTGLGVRIAYRILLFFDGSANNL
HHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCHHCCCHHEEEEEEEEEECCCCCHH
IGGILTTAALLSCIMPEHAVAALLFPIVIQISRSLNLKPMESQLGKALFLSLAWGAVIGG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ITTYLGGARNLLAVDILQKNYHISIGFVNWILMALPIPIIILILAYFTITYFFKPEITDS
HHHHHCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
VEAKKKLEKIMGNQGQLSKSEKKLIAVLIMVILMWLLLSSRVDIAITALLGGVAIFVLDI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VKWKDIVDYVNWGVIFMYGGAIVVASSLSITGAAAWLSSTIFSSISVSPFIFIAVITLVT
HHHHHHHHHHCCCCEEEECCHHEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KLLTEGISNVAAVAIILPLAFSWGEISQINPIATTLAVALSGGLAFCLPMGTPPNAIAFS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEC
AGYYRISDVLKVGVILNIISWVVVLLISKFYWPLLGINL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA