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The map label for this gene is purR [H]

Identifier: 220932966

GI number: 220932966

Start: 2323114

End: 2323929

Strand: Reverse

Name: purR [H]

Synonym: Hore_21340

Alternate gene names: 220932966

Gene position: 2323929-2323114 (Counterclockwise)

Preceding gene: 220932967

Following gene: 220932962

Centisome position: 90.14

GC content: 42.52

Gene sequence:

>816_bases
ATGGAGGATTTCAAAAGAACCGAACGGCTTACAGCCCTGACCCAGATATTAGTAGACAACCCATATACTCTGTTTCCTTT
GCGGGGTTTTACAGAACGATTTCAGGTTGCCAAATCAACCCTCAGCGAAGATGTTTCTATTATTAAATCAGTGTTTAAGA
GGTTAAACCTCGGTAGAGTAGAAACCGTTACCGGGGTAGCAGGTGGAATAAGGTATATTCCTTATATTAAAGAAGATGAG
GAAAAAGAGATGTTAACCCAGATTGCCAGTGAATTATCCCGGGGAGAGAGGATACTCCCCGGTGGGTTTATTTATATGAC
TGACTTAATATTCTCGGCAGATATTGCCTGGAGAGTTGGGAAAATATTTGCCAGTAAATTTATAGATAAAAGACCCGATT
ATATAATTACGATAGAGACCAAGGGTATCCCTATCGCCATGATGACAGCCCGTGCCTTTAATGTTCCCCTTGTAACTATC
CGCCGCAATACCAGGGTTACCGAGGGGTCGGTTGTTACCATAAATTATGTCAGCGGGTCTTCGGGGAAAATACAGACCAT
GTCCTTATCACGGCGGGCCCTTCCGGAAGGATCTAAAGTTGTCTTCATTGATGATTTTATGAAGGCCGGTGGTACCGCCA
AAGGTGTATTGGAGTTAATGAAGGAATTTAAGGTTGAAGTGGCCGGGGTCGGTGTTCTGGTAGAAACCGCTCATCCCGGT
GATAAGTTAATAGATGATTATCTCTCTTTACTATTACTGGAAAAGGTTGATGAAAGAAATAAAAAGGTAGTAATCAGACC
CAGTCATCAAGCTTAA

Upstream 100 bases:

>100_bases
TGAACACCCTGAGATAGGATTTGATGTCGATAAACCAAGTGATCTAAAATTAATGAGGGATAAATATATATTATAAAAAT
TGCAGACTTGGGGGGAAAAC

Downstream 100 bases:

>100_bases
TATCTTTTGCTTTTTAATTGACGGTGTACTTCTTCTTTAATTTCATTAATGGTATGGGGATGGACAAGTTTGTAAGCGGT
CATTCTGGTATAAGTCTGAC

Product: pur operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MEDFKRTERLTALTQILVDNPYTLFPLRGFTERFQVAKSTLSEDVSIIKSVFKRLNLGRVETVTGVAGGIRYIPYIKEDE
EKEMLTQIASELSRGERILPGGFIYMTDLIFSADIAWRVGKIFASKFIDKRPDYIITIETKGIPIAMMTARAFNVPLVTI
RRNTRVTEGSVVTINYVSGSSGKIQTMSLSRRALPEGSKVVFIDDFMKAGGTAKGVLELMKEFKVEVAGVGVLVETAHPG
DKLIDDYLSLLLLEKVDERNKKVVIRPSHQA

Sequences:

>Translated_271_residues
MEDFKRTERLTALTQILVDNPYTLFPLRGFTERFQVAKSTLSEDVSIIKSVFKRLNLGRVETVTGVAGGIRYIPYIKEDE
EKEMLTQIASELSRGERILPGGFIYMTDLIFSADIAWRVGKIFASKFIDKRPDYIITIETKGIPIAMMTARAFNVPLVTI
RRNTRVTEGSVVTINYVSGSSGKIQTMSLSRRALPEGSKVVFIDDFMKAGGTAKGVLELMKEFKVEVAGVGVLVETAHPG
DKLIDDYLSLLLLEKVDERNKKVVIRPSHQA
>Mature_271_residues
MEDFKRTERLTALTQILVDNPYTLFPLRGFTERFQVAKSTLSEDVSIIKSVFKRLNLGRVETVTGVAGGIRYIPYIKEDE
EKEMLTQIASELSRGERILPGGFIYMTDLIFSADIAWRVGKIFASKFIDKRPDYIITIETKGIPIAMMTARAFNVPLVTI
RRNTRVTEGSVVTINYVSGSSGKIQTMSLSRRALPEGSKVVFIDDFMKAGGTAKGVLELMKEFKVEVAGVGVLVETAHPG
DKLIDDYLSLLLLEKVDERNKKVVIRPSHQA

Specific function: Controls the transcription of the pur operon for purine biosynthetic genes, binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR015265
- InterPro:   IPR010078
- InterPro:   IPR011991
- ProDom:   PD029816 [H]

Pfam domain/function: PF00156 Pribosyltran; PF09182 PuR_N [H]

EC number: NA

Molecular weight: Translated: 30296; Mature: 30296

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDFKRTERLTALTQILVDNPYTLFPLRGFTERFQVAKSTLSEDVSIIKSVFKRLNLGRV
CCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ETVTGVAGGIRYIPYIKEDEEKEMLTQIASELSRGERILPGGFIYMTDLIFSADIAWRVG
EHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHH
KIFASKFIDKRPDYIITIETKGIPIAMMTARAFNVPLVTIRRNTRVTEGSVVTINYVSGS
HHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHCCCCEEEEECCCEECCCCEEEEEEEECC
SGKIQTMSLSRRALPEGSKVVFIDDFMKAGGTAKGVLELMKEFKVEVAGVGVLVETAHPG
CCEEEEEECHHHCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHEEEEEEEEEEECCCC
DKLIDDYLSLLLLEKVDERNKKVVIRPSHQA
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
>Mature Secondary Structure
MEDFKRTERLTALTQILVDNPYTLFPLRGFTERFQVAKSTLSEDVSIIKSVFKRLNLGRV
CCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ETVTGVAGGIRYIPYIKEDEEKEMLTQIASELSRGERILPGGFIYMTDLIFSADIAWRVG
EHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHH
KIFASKFIDKRPDYIITIETKGIPIAMMTARAFNVPLVTIRRNTRVTEGSVVTINYVSGS
HHHHHHHHCCCCCEEEEEECCCCCEEEEEEHHCCCCEEEEECCCEECCCCEEEEEEEECC
SGKIQTMSLSRRALPEGSKVVFIDDFMKAGGTAKGVLELMKEFKVEVAGVGVLVETAHPG
CCEEEEEECHHHCCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHEEEEEEEEEEECCCC
DKLIDDYLSLLLLEKVDERNKKVVIRPSHQA
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7638212 [H]