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The map label for this gene is ccpA [H]

Identifier: 220932920

GI number: 220932920

Start: 2261763

End: 2262794

Strand: Reverse

Name: ccpA [H]

Synonym: Hore_20880

Alternate gene names: 220932920

Gene position: 2262794-2261763 (Counterclockwise)

Preceding gene: 220932925

Following gene: 220932919

Centisome position: 87.77

GC content: 38.66

Gene sequence:

>1032_bases
ATGGCTGTAACAATGAAAGATGTTGCAAAACTTGCAGGAGTTTCCCCGAGCACCGTATCCCGTGTCCTTAATAACAGTTC
CCTGGTTAAAGAGGATACGGCGCGGAGGGTAATGGAAGCTGTAAAAAAACTTAATTATGAAATAAATGATCAGGCCCGTA
TACTCCGTACTAACTCAAGTCGATTAATCGGGATGATCGGGGCTGGAATGGAAAACCCATTTCTGGCCAAGGTTCTTAAA
GGTGTTGAGAATGAAGCCAGGCAGCGTAATTATAACATTATATATGGTGATTCTGATGGAGAGCTTAAACTTGAACTAAA
ATTTCTAAAAATTATGAAGCAGCGGAAAATTGACGGAATAATTATAATTTCAGCAAATATATACAGTAGCCTCCTGGAAA
AGGTTAAGGAAAGTGAAATACCGGTGGTATTTGGTTCAGGTTATATTAATGATCCTGATATTTCCTGTGTTACCGTGGAT
AACGTAACTGCAGCCTATGAAGCGGTTGATTATCTGGTCAATAATGGCCATAAAAAAATAGGTGTTATCCAGGGTCCTTA
TTCAGATGCGGTGGCTAGTGCTGAAAGAATTAAAGGTGTTAGACTTGCCTTTAGAAATCATGGAATAGAGTTAGACGATA
AGCTAATTGCAGAGGGAGATTATACTTTTGAAAGTGGTTATACAGGGGCAAAGGAATTATTATCAAGGAATAATGATTTG
ACCGCTATTTTTGCGTTTAATGATGAAATGGCAATAGGGGCTATCCGTTATCTTCAAGAGTCGGGAATTTCTATTCCCCG
TGATATTTCAGTAATTGGTTTTGATGGTATTGATTTATCTAAATTTGTTAAACCAGCACTTACTACTGTAGAACAATCTG
GTTATGAGCTGGGGAGTAAAGCTGTTGAAATGCTGGATAGTTTAATTCAGGGCAAACCCCTTTCAAATAATAAGATTTTT
ATTCCCCATAAACTTGTGGAAAGGGAAAGCACCGAAATGCATTTCGGGGAGGTGGTAGGTAAGAGGAGGTGA

Upstream 100 bases:

>100_bases
TTAAAAAATTTAAATAAAAAAGAAGGAATTTTGGATTTTGTCTTGAAATATATAAATGAAATGGATTTCATTATATAGGG
TTAAAAGGGGTTAGATACAT

Downstream 100 bases:

>100_bases
TGACTGGCAATTGATTTTAATTAATAGTTAACTTTAAAAATTACTAAAGGGGGAGACAATTAATGAAAAAAGGGTTATCT
TTAATACTTGTTATTTCATT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAVTMKDVAKLAGVSPSTVSRVLNNSSLVKEDTARRVMEAVKKLNYEINDQARILRTNSSRLIGMIGAGMENPFLAKVLK
GVENEARQRNYNIIYGDSDGELKLELKFLKIMKQRKIDGIIIISANIYSSLLEKVKESEIPVVFGSGYINDPDISCVTVD
NVTAAYEAVDYLVNNGHKKIGVIQGPYSDAVASAERIKGVRLAFRNHGIELDDKLIAEGDYTFESGYTGAKELLSRNNDL
TAIFAFNDEMAIGAIRYLQESGISIPRDISVIGFDGIDLSKFVKPALTTVEQSGYELGSKAVEMLDSLIQGKPLSNNKIF
IPHKLVERESTEMHFGEVVGKRR

Sequences:

>Translated_343_residues
MAVTMKDVAKLAGVSPSTVSRVLNNSSLVKEDTARRVMEAVKKLNYEINDQARILRTNSSRLIGMIGAGMENPFLAKVLK
GVENEARQRNYNIIYGDSDGELKLELKFLKIMKQRKIDGIIIISANIYSSLLEKVKESEIPVVFGSGYINDPDISCVTVD
NVTAAYEAVDYLVNNGHKKIGVIQGPYSDAVASAERIKGVRLAFRNHGIELDDKLIAEGDYTFESGYTGAKELLSRNNDL
TAIFAFNDEMAIGAIRYLQESGISIPRDISVIGFDGIDLSKFVKPALTTVEQSGYELGSKAVEMLDSLIQGKPLSNNKIF
IPHKLVERESTEMHFGEVVGKRR
>Mature_342_residues
AVTMKDVAKLAGVSPSTVSRVLNNSSLVKEDTARRVMEAVKKLNYEINDQARILRTNSSRLIGMIGAGMENPFLAKVLKG
VENEARQRNYNIIYGDSDGELKLELKFLKIMKQRKIDGIIIISANIYSSLLEKVKESEIPVVFGSGYINDPDISCVTVDN
VTAAYEAVDYLVNNGHKKIGVIQGPYSDAVASAERIKGVRLAFRNHGIELDDKLIAEGDYTFESGYTGAKELLSRNNDLT
AIFAFNDEMAIGAIRYLQESGISIPRDISVIGFDGIDLSKFVKPALTTVEQSGYELGSKAVEMLDSLIQGKPLSNNKIFI
PHKLVERESTEMHFGEVVGKRR

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=34.7432024169184, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=32.6219512195122, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=33.7386018237082, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1788474, Length=336, Percent_Identity=33.9285714285714, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1789068, Length=333, Percent_Identity=30.9309309309309, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=30.5135951661631, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1789202, Length=329, Percent_Identity=30.3951367781155, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=29.7297297297297, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787906, Length=338, Percent_Identity=28.698224852071, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789456, Length=344, Percent_Identity=28.1976744186047, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI48994940, Length=315, Percent_Identity=25.7142857142857, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=24.375, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790689, Length=325, Percent_Identity=26.4615384615385, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790192, Length=259, Percent_Identity=28.1853281853282, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786268, Length=320, Percent_Identity=22.5, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37844; Mature: 37713

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS51063 HTH_CRP_2 ; PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTMKDVAKLAGVSPSTVSRVLNNSSLVKEDTARRVMEAVKKLNYEINDQARILRTNSS
CCCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
RLIGMIGAGMENPFLAKVLKGVENEARQRNYNIIYGDSDGELKLELKFLKIMKQRKIDGI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEHHHHHHHHCCCCEE
IIISANIYSSLLEKVKESEIPVVFGSGYINDPDISCVTVDNVTAAYEAVDYLVNNGHKKI
EEEECHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEE
GVIQGPYSDAVASAERIKGVRLAFRNHGIELDDKLIAEGDYTFESGYTGAKELLSRNNDL
EEEECCCHHHHHHHHHHHHHHEEHHHCCCCCCCCEEECCCCEECCCCCCHHHHHHCCCCE
TAIFAFNDEMAIGAIRYLQESGISIPRDISVIGFDGIDLSKFVKPALTTVEQSGYELGSK
EEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
AVEMLDSLIQGKPLSNNKIFIPHKLVERESTEMHFGEVVGKRR
HHHHHHHHHCCCCCCCCEEECCHHHHCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
AVTMKDVAKLAGVSPSTVSRVLNNSSLVKEDTARRVMEAVKKLNYEINDQARILRTNSS
CCCHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
RLIGMIGAGMENPFLAKVLKGVENEARQRNYNIIYGDSDGELKLELKFLKIMKQRKIDGI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEHHHHHHHHCCCCEE
IIISANIYSSLLEKVKESEIPVVFGSGYINDPDISCVTVDNVTAAYEAVDYLVNNGHKKI
EEEECHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEE
GVIQGPYSDAVASAERIKGVRLAFRNHGIELDDKLIAEGDYTFESGYTGAKELLSRNNDL
EEEECCCHHHHHHHHHHHHHHEEHHHCCCCCCCCEEECCCCEECCCCCCHHHHHHCCCCE
TAIFAFNDEMAIGAIRYLQESGISIPRDISVIGFDGIDLSKFVKPALTTVEQSGYELGSK
EEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
AVEMLDSLIQGKPLSNNKIFIPHKLVERESTEMHFGEVVGKRR
HHHHHHHHHCCCCCCCCEEECCHHHHCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]