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The map label for this gene is xylB [H]

Identifier: 220932785

GI number: 220932785

Start: 2091373

End: 2092878

Strand: Reverse

Name: xylB [H]

Synonym: Hore_19510

Alternate gene names: 220932785

Gene position: 2092878-2091373 (Counterclockwise)

Preceding gene: 220932786

Following gene: 220932784

Centisome position: 81.18

GC content: 43.96

Gene sequence:

>1506_bases
TTGGGTTATTTAATTGGTCTCGATATCGGAACAAGTGGTGTCAAGGGTATCCTTGTTTCCGTTACAGGTGATATAGTTGC
ATCCAGGACTGAAGGTTACCCCCTGGCGACCCCCAATCCAGGCTGGGCGGAACAGGATCCTGAGGACTGGTGGCAGGCTA
CAAAAAAGGTAATCAATGGCCTTCTTACTGATAGTCAAATTGATCCTGGAACAGTCAGGGGAATCAGTCTTTCAGGACAG
ATGCACAGCTCTGTTTTTCTCAATGATAAAATGGAGGTTATTAGACCGGCTATTCTCTGGAGTGATACCCGTACCACCAG
GCAGTGTCAGGAAATTTATAACCGGGTTGATGGTTTAGAATCATTAATAGATCTGGTTTCTAACCCGGCTCTGGAAGGGT
TTACTGCTCCCAAGATATTGTGGTTACGGGACAATGAGCCTGAAAATTTCGAAGAAGTTAAGCTTGTTTTATTACCCAAA
GACTATATCAGGTATAAGCTGACCGGAGAGATAAATACTGAAGTATCCGATGCAGCCGGGACTCTGTTACTGGATGTAGT
TGAAAAGGATTGGTCAAAAGAGATTTTAGACAGACTCAATCTTGACAGGGAGATGTTACCTCCTGTCCTGGATTCCACTG
AAATTGCCGGTAAAGTATTACCTGGGGTGGCAGTAGAAACCGGGTTGAAACCGGGGACACCGGTAGTAGCCGGTGGAGCT
GATAATGCCTGTGGAGCTGTAGGTAGTGGTATTGTAAGCGAAGGAAGGGTTATGGTCAGTGTTGGTTCGTCTGGAGTAGT
TTTGGCCCAGGCCAATAACCCGAGAGCTGATAAGCAGGGAAGGATCCATCTCTTTAACCACGCTGCCCCTGATAAATGGT
ATATGATGGGGGTTATGCTCTCAGCAGGAATGTCTTTTAAATGGATGAAGGAAAAGATGTTCAATGACAGGCTGGATTAT
GATAAATTAAATGAGCTGGCAGATAGTGTTGACCCTGGTTGTGAAGGACTCCTCTTTTTACCCTATCTCTATGGAGAGAG
GACACCCCATGCTGATGCCAATGCCCGCGGGGTTTATTTTGGAATATCTGGTAAACACCATCAGGGGCATTTTATAAGAG
CGGTCATGGAAGGTGTTACCTTTGGATTGAAGGATTCTCTGGAATTAATTAAAGAAAAAGGAGTAACCATTAAGGAGATA
AGGGCTATAGGTGGTGGAGCTAAGAGTAGAATCTGGCAGCAGATTATGGCTGACATCTTCGGCCAGGAGATAAACCTCTT
AAATATTGAGGAAGGACCTGCCTTTGGAGCAGCTTTAATTGCCGGGGTTGGAGTAGGTGAGTATGCCAACTTTAAAGAAG
CTGAAGATAAGATAATTAAAGTTAGAAAAACTATTGAACCTGATTCCAATAATGTACAGCATTATAATGACCTCTATCAG
TTATACAGGAAGCTTTATACCAGCTTAAAGGATGACTTTAAGGCCCTGTCTGACCTCAATAATTAA

Upstream 100 bases:

>100_bases
GCATATGAAGTAGTCTATGAAGCACTGGGACTTGACAAAAGTTATATAGACAAGCTATATGACGAAAGGAAGAAACTATC
ATAAAGGATGGTGAGATAAG

Downstream 100 bases:

>100_bases
ATCAGATCCTTTTATATTTGATTTTTCTGTTCATAAACTGGTGATATAAATATTACGGTATATATGAACACAATTTATAA
TCTACTTAAGAGGAGGTGAT

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MGYLIGLDIGTSGVKGILVSVTGDIVASRTEGYPLATPNPGWAEQDPEDWWQATKKVINGLLTDSQIDPGTVRGISLSGQ
MHSSVFLNDKMEVIRPAILWSDTRTTRQCQEIYNRVDGLESLIDLVSNPALEGFTAPKILWLRDNEPENFEEVKLVLLPK
DYIRYKLTGEINTEVSDAAGTLLLDVVEKDWSKEILDRLNLDREMLPPVLDSTEIAGKVLPGVAVETGLKPGTPVVAGGA
DNACGAVGSGIVSEGRVMVSVGSSGVVLAQANNPRADKQGRIHLFNHAAPDKWYMMGVMLSAGMSFKWMKEKMFNDRLDY
DKLNELADSVDPGCEGLLFLPYLYGERTPHADANARGVYFGISGKHHQGHFIRAVMEGVTFGLKDSLELIKEKGVTIKEI
RAIGGGAKSRIWQQIMADIFGQEINLLNIEEGPAFGAALIAGVGVGEYANFKEAEDKIIKVRKTIEPDSNNVQHYNDLYQ
LYRKLYTSLKDDFKALSDLNN

Sequences:

>Translated_501_residues
MGYLIGLDIGTSGVKGILVSVTGDIVASRTEGYPLATPNPGWAEQDPEDWWQATKKVINGLLTDSQIDPGTVRGISLSGQ
MHSSVFLNDKMEVIRPAILWSDTRTTRQCQEIYNRVDGLESLIDLVSNPALEGFTAPKILWLRDNEPENFEEVKLVLLPK
DYIRYKLTGEINTEVSDAAGTLLLDVVEKDWSKEILDRLNLDREMLPPVLDSTEIAGKVLPGVAVETGLKPGTPVVAGGA
DNACGAVGSGIVSEGRVMVSVGSSGVVLAQANNPRADKQGRIHLFNHAAPDKWYMMGVMLSAGMSFKWMKEKMFNDRLDY
DKLNELADSVDPGCEGLLFLPYLYGERTPHADANARGVYFGISGKHHQGHFIRAVMEGVTFGLKDSLELIKEKGVTIKEI
RAIGGGAKSRIWQQIMADIFGQEINLLNIEEGPAFGAALIAGVGVGEYANFKEAEDKIIKVRKTIEPDSNNVQHYNDLYQ
LYRKLYTSLKDDFKALSDLNN
>Mature_500_residues
GYLIGLDIGTSGVKGILVSVTGDIVASRTEGYPLATPNPGWAEQDPEDWWQATKKVINGLLTDSQIDPGTVRGISLSGQM
HSSVFLNDKMEVIRPAILWSDTRTTRQCQEIYNRVDGLESLIDLVSNPALEGFTAPKILWLRDNEPENFEEVKLVLLPKD
YIRYKLTGEINTEVSDAAGTLLLDVVEKDWSKEILDRLNLDREMLPPVLDSTEIAGKVLPGVAVETGLKPGTPVVAGGAD
NACGAVGSGIVSEGRVMVSVGSSGVVLAQANNPRADKQGRIHLFNHAAPDKWYMMGVMLSAGMSFKWMKEKMFNDRLDYD
KLNELADSVDPGCEGLLFLPYLYGERTPHADANARGVYFGISGKHHQGHFIRAVMEGVTFGLKDSLELIKEKGVTIKEIR
AIGGGAKSRIWQQIMADIFGQEINLLNIEEGPAFGAALIAGVGVGEYANFKEAEDKIIKVRKTIEPDSNNVQHYNDLYQL
YRKLYTSLKDDFKALSDLNN

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=443, Percent_Identity=23.4762979683973, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI42794763, Length=443, Percent_Identity=23.9277652370203, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4504007, Length=443, Percent_Identity=23.7020316027088, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI189409120, Length=443, Percent_Identity=23.7020316027088, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI164663828, Length=558, Percent_Identity=23.8351254480287, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI88196792, Length=511, Percent_Identity=24.4618395303327, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI164663830, Length=582, Percent_Identity=23.0240549828179, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI18860918, Length=468, Percent_Identity=24.1452991452991, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1789987, Length=486, Percent_Identity=39.0946502057613, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1790005, Length=495, Percent_Identity=30.3030303030303, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787789, Length=504, Percent_Identity=25.5952380952381, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI1790361, Length=494, Percent_Identity=25.1012145748988, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1789168, Length=489, Percent_Identity=24.7443762781186, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789138, Length=494, Percent_Identity=23.2793522267206, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786249, Length=556, Percent_Identity=22.3021582733813, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17535599, Length=453, Percent_Identity=24.9448123620309, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17554530, Length=534, Percent_Identity=21.1610486891386, Blast_Score=95, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6321633, Length=411, Percent_Identity=23.1143552311436, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320314, Length=571, Percent_Identity=22.4168126094571, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24655555, Length=465, Percent_Identity=25.1612903225806, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24655560, Length=465, Percent_Identity=25.1612903225806, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24655570, Length=465, Percent_Identity=25.1612903225806, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24655574, Length=465, Percent_Identity=25.1612903225806, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24655565, Length=465, Percent_Identity=25.1612903225806, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17864214, Length=464, Percent_Identity=25.2155172413793, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI21356607, Length=555, Percent_Identity=24.8648648648649, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24654573, Length=388, Percent_Identity=25.7731958762887, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24657106, Length=540, Percent_Identity=22.5925925925926, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24657102, Length=540, Percent_Identity=22.5925925925926, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19922058, Length=494, Percent_Identity=22.6720647773279, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656367, Length=491, Percent_Identity=21.5885947046843, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24652871, Length=449, Percent_Identity=22.71714922049, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 55001; Mature: 54870

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYLIGLDIGTSGVKGILVSVTGDIVASRTEGYPLATPNPGWAEQDPEDWWQATKKVING
CCEEEEEECCCCCCCEEEEEEECCHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLTDSQIDPGTVRGISLSGQMHSSVFLNDKMEVIRPAILWSDTRTTRQCQEIYNRVDGLE
HHCCCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
SLIDLVSNPALEGFTAPKILWLRDNEPENFEEVKLVLLPKDYIRYKLTGEINTEVSDAAG
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHEEEEEECCCCCCHHHHHH
TLLLDVVEKDWSKEILDRLNLDREMLPPVLDSTEIAGKVLPGVAVETGLKPGTPVVAGGA
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEECCC
DNACGAVGSGIVSEGRVMVSVGSSGVVLAQANNPRADKQGRIHLFNHAAPDKWYMMGVML
CCCCHHHCCCHHCCCEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHH
SAGMSFKWMKEKMFNDRLDYDKLNELADSVDPGCEGLLFLPYLYGERTPHADANARGVYF
HCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCCCCEEEE
GISGKHHQGHFIRAVMEGVTFGLKDSLELIKEKGVTIKEIRAIGGGAKSRIWQQIMADIF
ECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHC
GQEINLLNIEEGPAFGAALIAGVGVGEYANFKEAEDKIIKVRKTIEPDSNNVQHYNDLYQ
CCCEEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LYRKLYTSLKDDFKALSDLNN
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GYLIGLDIGTSGVKGILVSVTGDIVASRTEGYPLATPNPGWAEQDPEDWWQATKKVING
CEEEEEECCCCCCCEEEEEEECCHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLTDSQIDPGTVRGISLSGQMHSSVFLNDKMEVIRPAILWSDTRTTRQCQEIYNRVDGLE
HHCCCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
SLIDLVSNPALEGFTAPKILWLRDNEPENFEEVKLVLLPKDYIRYKLTGEINTEVSDAAG
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECHHHEEEEEECCCCCCHHHHHH
TLLLDVVEKDWSKEILDRLNLDREMLPPVLDSTEIAGKVLPGVAVETGLKPGTPVVAGGA
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCHHHHCCCCCCCCEEECCC
DNACGAVGSGIVSEGRVMVSVGSSGVVLAQANNPRADKQGRIHLFNHAAPDKWYMMGVML
CCCCHHHCCCHHCCCEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHH
SAGMSFKWMKEKMFNDRLDYDKLNELADSVDPGCEGLLFLPYLYGERTPHADANARGVYF
HCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCCCCEEEE
GISGKHHQGHFIRAVMEGVTFGLKDSLELIKEKGVTIKEIRAIGGGAKSRIWQQIMADIF
ECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHC
GQEINLLNIEEGPAFGAALIAGVGVGEYANFKEAEDKIIKVRKTIEPDSNNVQHYNDLYQ
CCCEEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LYRKLYTSLKDDFKALSDLNN
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]