Definition Halothermothrix orenii H 168 chromosome, complete genome.
Accession NC_011899
Length 2,578,146

Click here to switch to the map view.

The map label for this gene is ucpA [C]

Identifier: 220932755

GI number: 220932755

Start: 2054231

End: 2054962

Strand: Reverse

Name: ucpA [C]

Synonym: Hore_19210

Alternate gene names: 220932755

Gene position: 2054962-2054231 (Counterclockwise)

Preceding gene: 220932756

Following gene: 220932754

Centisome position: 79.71

GC content: 42.9

Gene sequence:

>732_bases
ATGAAACTTGAAGGTAAAGTTGCTTTAATCACCGGAGCAAGTTCAGGGATTGGAGAGGGTATAGCCAGGAAATTTCTTGA
TGAGGGTGCCAGGATTATTGGTTGTGGAATTGAAGATGATATGAACCTTAAGGGCGAAAACACTCTATATGTAAAGGCAG
ATTTAACAGATTATAATCAGGCCCGGAAAGTTGTTGAAGAGGGTATTGCCAAATTTGGCCAACTTGATATAGTCGTTAAT
AGTGCCGGGATTACCGGGGTAGGAAATATAGAGACAACCTCTCCTGCAGAATTTGAAAAGCAGTTTGCAGTAAATGTATT
CGGGACCTTCAATACCTGTAAGGCGGCTGTTGGGGAGTTAAAAAAACGCCCCGGGGCCAGTATTATAAATATTGCTTCCG
ATCTGGGGGTAAAACCTATCCCTGACCGGATTGCTTACTGTCCTTCCAAAGCAGCCGTTGTAATGTTTACTAAATGTATG
GCTTTAGACCTTGGACCTGATATCAGGGTAAATGCCATAATGCCGGGCTTAACTGAAACCCCAATGATTAAAGATAGAAT
TGAAAAAGCAGATGACCCGGATCAGGTCAGGAAAGAGATGGCTGAAATGTATGTCCTGAAAAGGATGTGTACTGTAGATG
ATATTGCCAATGCAGCCCTGTTTTTAGCAACTGAAGATAGTGGTTTTATTACCGGAGATATGCTGGCTGTCTGTGGAGGA
GGGCAGCTGTAA

Upstream 100 bases:

>100_bases
CTATAAATATTCTAATTACGATTAATGGAAAAATATATTAATCAGGCCTGTCTCGGGTATACTTCAGGTAGGTTTAAACT
AAGTCCAGGGAGGGAATTTA

Downstream 100 bases:

>100_bases
GGTTCATTTCAATAAAACTGTAAGACAGTAGGGAGGGAGAATATAAATGTCATTAGTAAAAATTCCTTTTGACAGGGATA
AAATAAAGTTATCCAGGGTA

Product: 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKLEGKVALITGASSGIGEGIARKFLDEGARIIGCGIEDDMNLKGENTLYVKADLTDYNQARKVVEEGIAKFGQLDIVVN
SAGITGVGNIETTSPAEFEKQFAVNVFGTFNTCKAAVGELKKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCM
ALDLGPDIRVNAIMPGLTETPMIKDRIEKADDPDQVRKEMAEMYVLKRMCTVDDIANAALFLATEDSGFITGDMLAVCGG
GQL

Sequences:

>Translated_243_residues
MKLEGKVALITGASSGIGEGIARKFLDEGARIIGCGIEDDMNLKGENTLYVKADLTDYNQARKVVEEGIAKFGQLDIVVN
SAGITGVGNIETTSPAEFEKQFAVNVFGTFNTCKAAVGELKKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCM
ALDLGPDIRVNAIMPGLTETPMIKDRIEKADDPDQVRKEMAEMYVLKRMCTVDDIANAALFLATEDSGFITGDMLAVCGG
GQL
>Mature_243_residues
MKLEGKVALITGASSGIGEGIARKFLDEGARIIGCGIEDDMNLKGENTLYVKADLTDYNQARKVVEEGIAKFGQLDIVVN
SAGITGVGNIETTSPAEFEKQFAVNVFGTFNTCKAAVGELKKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCM
ALDLGPDIRVNAIMPGLTETPMIKDRIEKADDPDQVRKEMAEMYVLKRMCTVDDIANAALFLATEDSGFITGDMLAVCGG
GQL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=32.6848249027237, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=33.7719298245614, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=31.0204081632653, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI31542939, Length=211, Percent_Identity=30.8056872037915, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.5220883534137, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=30.327868852459, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66933014, Length=244, Percent_Identity=27.8688524590164, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=30.4597701149425, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=31.5533980582524, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI40254986, Length=191, Percent_Identity=32.4607329842932, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI186928839, Length=208, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=26.2948207171315, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=25.390625, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=26.5873015873016, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=27.363184079602, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4503817, Length=195, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=29.9492385786802, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI83715985, Length=205, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=24.8, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI225579078, Length=207, Percent_Identity=29.4685990338164, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=30.6878306878307, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI210032112, Length=226, Percent_Identity=26.9911504424779, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI166795268, Length=208, Percent_Identity=25.9615384615385, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4504505, Length=215, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI210032110, Length=239, Percent_Identity=26.7782426778243, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI10190746, Length=215, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4504503, Length=229, Percent_Identity=27.9475982532751, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=34.7826086956522, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=32.520325203252, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=30.8, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=32.6693227091633, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.9212598425197, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=31.7269076305221, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=28.6290322580645, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=28.2868525896414, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=29.0196078431373, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=28.6307053941909, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787820, Length=228, Percent_Identity=29.3859649122807, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=25.78125, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786701, Length=223, Percent_Identity=27.8026905829596, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=33.4645669291339, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=31.3492063492063, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=30.4878048780488, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=32.0987654320988, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=31.5789473684211, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=28.9156626506024, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.6992481203008, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=24.1935483870968, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.3703703703704, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=27.1698113207547, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=31.5589353612167, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=219, Percent_Identity=31.5068493150685, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=27.9245283018868, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=29.7794117647059, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=30.9701492537313, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=30.3703703703704, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=30.8550185873606, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=193, Percent_Identity=33.6787564766839, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=26.7206477732794, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=27.1375464684015, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=28.6792452830189, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=29.1187739463602, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=29.8507462686567, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=28.4644194756554, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=28.6458333333333, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17558006, Length=264, Percent_Identity=26.1363636363636, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=24.8704663212435, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=26.171875, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=24.8995983935743, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=33.1983805668016, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=34.5528455284553, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=33.6, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=35.4838709677419, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=31.9672131147541, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=32.5396825396825, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=30.7086614173228, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=36.4130434782609, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357673, Length=214, Percent_Identity=32.2429906542056, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=30.9278350515464, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641232, Length=240, Percent_Identity=25, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17737361, Length=218, Percent_Identity=29.3577981651376, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=26.9058295964126, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221331218, Length=208, Percent_Identity=26.4423076923077, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24665243, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571387, Length=239, Percent_Identity=26.7782426778243, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221331216, Length=209, Percent_Identity=26.7942583732057, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665247, Length=209, Percent_Identity=26.7942583732057, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24647946, Length=207, Percent_Identity=28.5024154589372, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25903; Mature: 25903

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKLEGKVALITGASSGIGEGIARKFLDEGARIIGCGIEDDMNLKGENTLYVKADLTDYNQ
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCCHHH
ARKVVEEGIAKFGQLDIVVNSAGITGVGNIETTSPAEFEKQFAVNVFGTFNTCKAAVGEL
HHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHEEEEEEECHHHHHHHHHHH
KKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCMALDLGPDIRVNAIMPGLTET
HCCCCCCEEEHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHEECCCCCEEEEECCCCCCC
PMIKDRIEKADDPDQVRKEMAEMYVLKRMCTVDDIANAALFLATEDSGFITGDMLAVCGG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCHHEECCC
GQL
CCC
>Mature Secondary Structure
MKLEGKVALITGASSGIGEGIARKFLDEGARIIGCGIEDDMNLKGENTLYVKADLTDYNQ
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCCHHH
ARKVVEEGIAKFGQLDIVVNSAGITGVGNIETTSPAEFEKQFAVNVFGTFNTCKAAVGEL
HHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHEEEEEEECHHHHHHHHHHH
KKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCMALDLGPDIRVNAIMPGLTET
HCCCCCCEEEHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHEECCCCCEEEEECCCCCCC
PMIKDRIEKADDPDQVRKEMAEMYVLKRMCTVDDIANAALFLATEDSGFITGDMLAVCGG
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCHHEECCC
GQL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]