Click here to switch to the map view.

The map label for this gene is mch [H]

Identifier: 220932756

GI number: 220932756

Start: 2055095

End: 2056066

Strand: Reverse

Name: mch [H]

Synonym: Hore_19220

Alternate gene names: 220932756

Gene position: 2056066-2055095 (Counterclockwise)

Preceding gene: 220932757

Following gene: 220932755

Centisome position: 79.75

GC content: 41.67

Gene sequence:

>972_bases
ATGATCAGTGTAAACGAAAAGGCAATGGAAATTGTTAATGATATGATTTTAAGAAAAGAAGAATTGAAGATTGAAGTGTC
AACATTAGAAAATGGAACTACTGTGATCGACCTGGGACAGGAGGTCAGAGGCAGCTGGGAAGCTGCCAGAATGATGGCAG
AGATTTTATTTGGTGGTATTGGGCAGGTTTCTTTTGAAACATTCCCGGAAATGATAGATGGAGTGTACTATCCTGCAGTT
AATGTAAGTGTTGACCATGCCGTTTTATCCCTGGCCGGGTGTGATATTTCTGGCTGGGAATTAAAACCTGGAAAATTTGC
TCCAATTGTTGCCGGACCAGGTCGGACCCTGGGAAGAAAGCCCGGAGACTGGATGGAGAAATACAGTGATTATGAAGATA
AATATCACCAGGCCATTATTACTATCGAATCTAAAGACCCTGTTAGCGTAGAACAGGCCAGTGAACTGGCCGAGGCCTGC
CGGGTCCAGCCAGAAGATCTGTATTTACTGGTAGCTCCCAGTTCCAGTCTGGCCTGTTCCGTTCAGGTGTCAGCCAGAAT
TTTAGAACAGACCCTGCACCGCTTAATGGAAGAAGGGTTTGATCTGGACACAATAATTCAGGCCCAGGGTTTCTGTGTAA
TACCCCCCTGTATTGATAATGAATTAATTGCCATGGGAAGGTTAAATGATGTTCTTATATATGGAGGTCAGGCTACCTAT
ACTGTTTGCTGGGATGACGATAAAATTGCTGATATAGTTAATAAAATTACTTCAGATAAGGCTTCTACTTATGGTAAGCC
TTTTAAAGAAATATACCTGGAAGCCGGTTGTGATTTTTATCAAGTTCCTATGGAAATGTATTCTCCGGCCAGTGTAGTCA
TTGTTAATACCAAGACAGGTAAGATACATAAGGCCGGTAAAATAAATACTGAAATTTTAGCCAGGTCTTTTAATGATACT
GTTTCAGGCTAA

Upstream 100 bases:

>100_bases
AATCAATACATTTAGTTAATTTAAATCGATACATTTCAGGATATGTAGTTTCATAATCGGTCAGTTAGTAGAAATGCTAG
TCATTAATAGGAGGGATAAT

Downstream 100 bases:

>100_bases
ATAATGTTTAGCCTGAGTAGTATTTAATATTACTATAAATATTCTAATTACGATTAATGGAAAAATATATTAATCAGGCC
TGTCTCGGGTATACTTCAGG

Product: N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase

Products: NA

Alternate protein names: Methenyl-H4MPT cyclohydrolase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MISVNEKAMEIVNDMILRKEELKIEVSTLENGTTVIDLGQEVRGSWEAARMMAEILFGGIGQVSFETFPEMIDGVYYPAV
NVSVDHAVLSLAGCDISGWELKPGKFAPIVAGPGRTLGRKPGDWMEKYSDYEDKYHQAIITIESKDPVSVEQASELAEAC
RVQPEDLYLLVAPSSSLACSVQVSARILEQTLHRLMEEGFDLDTIIQAQGFCVIPPCIDNELIAMGRLNDVLIYGGQATY
TVCWDDDKIADIVNKITSDKASTYGKPFKEIYLEAGCDFYQVPMEMYSPASVVIVNTKTGKIHKAGKINTEILARSFNDT
VSG

Sequences:

>Translated_323_residues
MISVNEKAMEIVNDMILRKEELKIEVSTLENGTTVIDLGQEVRGSWEAARMMAEILFGGIGQVSFETFPEMIDGVYYPAV
NVSVDHAVLSLAGCDISGWELKPGKFAPIVAGPGRTLGRKPGDWMEKYSDYEDKYHQAIITIESKDPVSVEQASELAEAC
RVQPEDLYLLVAPSSSLACSVQVSARILEQTLHRLMEEGFDLDTIIQAQGFCVIPPCIDNELIAMGRLNDVLIYGGQATY
TVCWDDDKIADIVNKITSDKASTYGKPFKEIYLEAGCDFYQVPMEMYSPASVVIVNTKTGKIHKAGKINTEILARSFNDT
VSG
>Mature_323_residues
MISVNEKAMEIVNDMILRKEELKIEVSTLENGTTVIDLGQEVRGSWEAARMMAEILFGGIGQVSFETFPEMIDGVYYPAV
NVSVDHAVLSLAGCDISGWELKPGKFAPIVAGPGRTLGRKPGDWMEKYSDYEDKYHQAIITIESKDPVSVEQASELAEAC
RVQPEDLYLLVAPSSSLACSVQVSARILEQTLHRLMEEGFDLDTIIQAQGFCVIPPCIDNELIAMGRLNDVLIYGGQATY
TVCWDDDKIADIVNKITSDKASTYGKPFKEIYLEAGCDFYQVPMEMYSPASVVIVNTKTGKIHKAGKINTEILARSFNDT
VSG

Specific function: Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT(+) [H]

COG id: COG3252

COG function: function code H; Methenyltetrahydromethanopterin cyclohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MCH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003209 [H]

Pfam domain/function: PF02289 MCH [H]

EC number: =3.5.4.27 [H]

Molecular weight: Translated: 35569; Mature: 35569

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVNEKAMEIVNDMILRKEELKIEVSTLENGTTVIDLGQEVRGSWEAARMMAEILFGGI
CCCCCHHHHHHHHHHHHCHHHHEEEEEECCCCCEEEECCHHHCCCHHHHHHHHHHHHCCC
GQVSFETFPEMIDGVYYPAVNVSVDHAVLSLAGCDISGWELKPGKFAPIVAGPGRTLGRK
CCCHHHHHHHHHCCEECCEEECCHHHHHHEEECCCCCCCEECCCCEEEEEECCCCCCCCC
PGDWMEKYSDYEDKYHQAIITIESKDPVSVEQASELAEACRVQPEDLYLLVAPSSSLACS
CCHHHHHHCCHHHHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEE
VQVSARILEQTLHRLMEEGFDLDTIIQAQGFCVIPPCIDNELIAMGRLNDVLIYGGQATY
EHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCCCCEEEECCCCEEEEECCCEEE
TVCWDDDKIADIVNKITSDKASTYGKPFKEIYLEAGCDFYQVPMEMYSPASVVIVNTKTG
EEEECCCHHHHHHHHHHCCHHHHCCCHHHHHHHHCCCCCEECCHHHCCCCEEEEEECCCC
KIHKAGKINTEILARSFNDTVSG
CEECCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MISVNEKAMEIVNDMILRKEELKIEVSTLENGTTVIDLGQEVRGSWEAARMMAEILFGGI
CCCCCHHHHHHHHHHHHCHHHHEEEEEECCCCCEEEECCHHHCCCHHHHHHHHHHHHCCC
GQVSFETFPEMIDGVYYPAVNVSVDHAVLSLAGCDISGWELKPGKFAPIVAGPGRTLGRK
CCCHHHHHHHHHCCEECCEEECCHHHHHHEEECCCCCCCEECCCCEEEEEECCCCCCCCC
PGDWMEKYSDYEDKYHQAIITIESKDPVSVEQASELAEACRVQPEDLYLLVAPSSSLACS
CCHHHHHHCCHHHHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEE
VQVSARILEQTLHRLMEEGFDLDTIIQAQGFCVIPPCIDNELIAMGRLNDVLIYGGQATY
EHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCCCCEEEECCCCEEEEECCCEEE
TVCWDDDKIADIVNKITSDKASTYGKPFKEIYLEAGCDFYQVPMEMYSPASVVIVNTKTG
EEEECCCHHHHHHHHHHCCHHHHCCCHHHHHHHHCCCCCEECCHHHCCCCEEEEEECCCC
KIHKAGKINTEILARSFNDTVSG
CEECCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9676239; 11930014; 10545331 [H]