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The map label for this gene is ppaX [H]

Identifier: 220932752

GI number: 220932752

Start: 2051246

End: 2051902

Strand: Reverse

Name: ppaX [H]

Synonym: Hore_19180

Alternate gene names: 220932752

Gene position: 2051902-2051246 (Counterclockwise)

Preceding gene: 220932753

Following gene: 220932751

Centisome position: 79.59

GC content: 40.49

Gene sequence:

>657_bases
ATGATAAAGGGTATTATTTTTGATTTTGACGGGACTCTTTTTAATACCAATGACCTTATTAAAGAGTCTTTTTCCTATAG
CTTAAAAAAGGTATTGAACCGCGATCTTGAGGAAGGAGAGCTCAGGGAAATCTGGGGGGAACCCCTGGAAGACCAGATGA
AATATTTTAACAAAAAGAAGTGGTCTGATCTGGTAGATACCTATCGTAAGTTTTATCATGACCATACCGGGATGATGGAT
ACCTTTCCCGGGGCCCTGAAAACTGTAAGGCAACTCCATAACCTGGGGTATAAACTGGCCATTTTAACCAATAAGGGGAA
ACGGGGCCTGATAGAAGGTCTGCAGGAGTTTGGAATGCTCGAGGATATAGATTTTTACCTCAGTAAAGATGATGTGAACA
GGAGCAAACCTCATCCAGAAGGTTTTGTTAAAATAATGGAGAGGTTTGATTTAAATCCGGAAGAATTGTTAATGGTTGGT
GATAGCCCTTCAGATATTATTGGAGGGAAAAATGCCGGTCTGAAGACAGTTCTGGTATCATATACTTACTATGAAATGGA
AGATATGATAGCCCTTGAGCCTGATTATGTAATTGATCATCTGGAGGAGGTTATTGAACTGGTCGAGGGCTGCCGGGATA
AAATTGCAAGTCTTTAG

Upstream 100 bases:

>100_bases
GATAATGTTCACAAAAATATTCTGGAGCTGTAATTAGAGGAATTTTAAGTTTAATAGCAAATTAATATGAATAAGGTTAT
TTAAAAGGAGAGAGTGGGTA

Downstream 100 bases:

>100_bases
GGGGAGAGTTGATGGTTTTTAGAAAACTGGATACAAAAGATAATAAATATGTTATGGAGTTTCTGTCTGAAGAACCGGAG
TTTAACTTGTTTATAATAGG

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIKGIIFDFDGTLFNTNDLIKESFSYSLKKVLNRDLEEGELREIWGEPLEDQMKYFNKKKWSDLVDTYRKFYHDHTGMMD
TFPGALKTVRQLHNLGYKLAILTNKGKRGLIEGLQEFGMLEDIDFYLSKDDVNRSKPHPEGFVKIMERFDLNPEELLMVG
DSPSDIIGGKNAGLKTVLVSYTYYEMEDMIALEPDYVIDHLEEVIELVEGCRDKIASL

Sequences:

>Translated_218_residues
MIKGIIFDFDGTLFNTNDLIKESFSYSLKKVLNRDLEEGELREIWGEPLEDQMKYFNKKKWSDLVDTYRKFYHDHTGMMD
TFPGALKTVRQLHNLGYKLAILTNKGKRGLIEGLQEFGMLEDIDFYLSKDDVNRSKPHPEGFVKIMERFDLNPEELLMVG
DSPSDIIGGKNAGLKTVLVSYTYYEMEDMIALEPDYVIDHLEEVIELVEGCRDKIASL
>Mature_218_residues
MIKGIIFDFDGTLFNTNDLIKESFSYSLKKVLNRDLEEGELREIWGEPLEDQMKYFNKKKWSDLVDTYRKFYHDHTGMMD
TFPGALKTVRQLHNLGYKLAILTNKGKRGLIEGLQEFGMLEDIDFYLSKDDVNRSKPHPEGFVKIMERFDLNPEELLMVG
DSPSDIIGGKNAGLKTVLVSYTYYEMEDMIALEPDYVIDHLEEVIELVEGCRDKIASL

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=237, Percent_Identity=24.0506329113924, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 25236; Mature: 25236

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGIIFDFDGTLFNTNDLIKESFSYSLKKVLNRDLEEGELREIWGEPLEDQMKYFNKKK
CCCEEEEECCCCEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHH
WSDLVDTYRKFYHDHTGMMDTFPGALKTVRQLHNLGYKLAILTNKGKRGLIEGLQEFGML
HHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCH
EDIDFYLSKDDVNRSKPHPEGFVKIMERFDLNPEELLMVGDSPSDIIGGKNAGLKTVLVS
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHEEEECCCCCHHCCCCCCCHHHHHHH
YTYYEMEDMIALEPDYVIDHLEEVIELVEGCRDKIASL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKGIIFDFDGTLFNTNDLIKESFSYSLKKVLNRDLEEGELREIWGEPLEDQMKYFNKKK
CCCEEEEECCCCEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHH
WSDLVDTYRKFYHDHTGMMDTFPGALKTVRQLHNLGYKLAILTNKGKRGLIEGLQEFGML
HHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCH
EDIDFYLSKDDVNRSKPHPEGFVKIMERFDLNPEELLMVGDSPSDIIGGKNAGLKTVLVS
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHEEEECCCCCHHCCCCCCCHHHHHHH
YTYYEMEDMIALEPDYVIDHLEEVIELVEGCRDKIASL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]