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The map label for this gene is cobO [H]

Identifier: 220932733

GI number: 220932733

Start: 2028046

End: 2028573

Strand: Reverse

Name: cobO [H]

Synonym: Hore_18980

Alternate gene names: 220932733

Gene position: 2028573-2028046 (Counterclockwise)

Preceding gene: 220932734

Following gene: 220932732

Centisome position: 78.68

GC content: 39.58

Gene sequence:

>528_bases
ATGAAAAAGGGACTGGTTCATATATACACCGGAGACGGTAAAGGGAAAACTACGGCTGCAGTTGGTTTAGCAGTAAGGTC
AGCAGGGTATGGCAAAAAGATATATATATTACAATTCTTAAAGGGGCGGAAAACAGGGGAAAAGAAATTTTTTGAAAAGG
TAACCGATATTACTCTGGAGCGGGCCAACAAATCTACCAAATTTTTTTTCCAGATGTCAGATGAGGAGAAACAAAAGGTT
TTTGCAGAGACAAAAAAGGTCTGGGATAAGCTCAAGGATATTGTCAGGGATGGTGAATATGAAGTAGTTATTTTAGATGA
AATTATGGAGGCCATTGCCAATGGCCTGGTACAGACAGGCCAGGTTAAGGAATTAATTGCCATAAAGGATGAAAGCCTGG
AACTGATTTTAACCGGTCGTGATGCTCCTGAAGAACTGGTTGAACTGGCAGATTATGTTACTGAAATGAAGATGATAAAA
CATCCCTATAACCGTCAAATACCTGCCAGGAAGGGAATAGAATTTTAA

Upstream 100 bases:

>100_bases
CGGGGGCGGTTTTCGTTTAAATAGAGGTTTTTACTGTAAAATAAAGAATGTAATAATTAAATAACCGGGTCGGTAAAATA
AATTAAGGGAGGAAGTTGAA

Downstream 100 bases:

>100_bases
ATATTTGCAGGAAAATTGCTGTTTTTGTTGAATATTTATTAAGGTTGTCTGTAATTACAAGTTCATCAGGATTATAAGCT
TTAGGAGGGAAGAATTATGG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKKGLVHIYTGDGKGKTTAAVGLAVRSAGYGKKIYILQFLKGRKTGEKKFFEKVTDITLERANKSTKFFFQMSDEEKQKV
FAETKKVWDKLKDIVRDGEYEVVILDEIMEAIANGLVQTGQVKELIAIKDESLELILTGRDAPEELVELADYVTEMKMIK
HPYNRQIPARKGIEF

Sequences:

>Translated_175_residues
MKKGLVHIYTGDGKGKTTAAVGLAVRSAGYGKKIYILQFLKGRKTGEKKFFEKVTDITLERANKSTKFFFQMSDEEKQKV
FAETKKVWDKLKDIVRDGEYEVVILDEIMEAIANGLVQTGQVKELIAIKDESLELILTGRDAPEELVELADYVTEMKMIK
HPYNRQIPARKGIEF
>Mature_175_residues
MKKGLVHIYTGDGKGKTTAAVGLAVRSAGYGKKIYILQFLKGRKTGEKKFFEKVTDITLERANKSTKFFFQMSDEEKQKV
FAETKKVWDKLKDIVRDGEYEVVILDEIMEAIANGLVQTGQVKELIAIKDESLELILTGRDAPEELVELADYVTEMKMIK
HPYNRQIPARKGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=175, Percent_Identity=31.4285714285714, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19907; Mature: 19907

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGLVHIYTGDGKGKTTAAVGLAVRSAGYGKKIYILQFLKGRKTGEKKFFEKVTDITLE
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEHEEEEHHCCCCHHHHHHHHHHHHHHH
RANKSTKFFFQMSDEEKQKVFAETKKVWDKLKDIVRDGEYEVVILDEIMEAIANGLVQTG
HCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCC
QVKELIAIKDESLELILTGRDAPEELVELADYVTEMKMIKHPYNRQIPARKGIEF
CHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKGLVHIYTGDGKGKTTAAVGLAVRSAGYGKKIYILQFLKGRKTGEKKFFEKVTDITLE
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEHEEEEHHCCCCHHHHHHHHHHHHHHH
RANKSTKFFFQMSDEEKQKVFAETKKVWDKLKDIVRDGEYEVVILDEIMEAIANGLVQTG
HCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCC
QVKELIAIKDESLELILTGRDAPEELVELADYVTEMKMIKHPYNRQIPARKGIEF
CHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]