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The map label for this gene is crp [H]

Identifier: 220932652

GI number: 220932652

Start: 1938086

End: 1938745

Strand: Reverse

Name: crp [H]

Synonym: Hore_18160

Alternate gene names: 220932652

Gene position: 1938745-1938086 (Counterclockwise)

Preceding gene: 220932653

Following gene: 220932651

Centisome position: 75.2

GC content: 39.55

Gene sequence:

>660_bases
ATGAGTGAGATTAGTTACCGTTCTATTCCCCTTTTTTCAGGGCTTAACGATGAACAACTTGACCTCTTGAAAAGTATTAC
CAATAAGAGAAGATATAAAGCCGGTGAAATACTTTTTTTTGAGGGTGATAAGCCCGATGCTTTTTATATAGTGGTAGAAG
GGGAGATTCAGATAATAAAAGTTTCATATGACGGCAAGGAAAAAATTCTGGAGGTCATGGGTCCCGGTGACTTCTTTGGA
GAGATGGCTATTATTGATAGTAAAGGGCGTTCAGCTACAGCCAGGGTTATCCGGGATTCCAGTCTTCTGGTTGTCGGAAA
CCAGGAATTTTTAAACCTGGTCAGGGAATACCCCTTTATTGCCCTTAAAATTATTGGAGAATTAAGCCGGAGGTTGCGGC
AGGCCAATCAGGATATAGAGAGCCTTGCTTTTCTGGATGTTGAAACCCGGTTAAAAAAGTTTTTCAGGCGAATGACTGGT
GAGATCCGGGATAACGGAGAAGCAGTAGTTATAGACAGGAATATAACACACCAGGATATTGCCAGATTTATCGGGACTTC
CCGGGAGACAGTAACCCGGATTATAAATAAACTTAAAGATAAAGGGTTATTAGAAATTAAAAGAGAGAAAATAATTTTAA
AAGATATCAATAAATGGTGA

Upstream 100 bases:

>100_bases
ATAAGAATACAAATAAATCAAATCCAGGAGTTCTGGCAAAAACCTCAAAGAAAAAATGAGTAGAGTTTTAGATTTAAATG
TTATTGAAAGGGGCTTTTTG

Downstream 100 bases:

>100_bases
TGAAGGTCACTTTCCTCCCTGAGTATATTTGTAATAATATAATTGCAGGATGCAGTTATTTACCGGGTGCTTCATAATTT
ATTTTTCTGGTTTTTGCTCC

Product: putative Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: cAMP receptor protein; cAMP regulatory protein [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSEISYRSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIKVSYDGKEKILEVMGPGDFFG
EMAIIDSKGRSATARVIRDSSLLVVGNQEFLNLVREYPFIALKIIGELSRRLRQANQDIESLAFLDVETRLKKFFRRMTG
EIRDNGEAVVIDRNITHQDIARFIGTSRETVTRIINKLKDKGLLEIKREKIILKDINKW

Sequences:

>Translated_219_residues
MSEISYRSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIKVSYDGKEKILEVMGPGDFFG
EMAIIDSKGRSATARVIRDSSLLVVGNQEFLNLVREYPFIALKIIGELSRRLRQANQDIESLAFLDVETRLKKFFRRMTG
EIRDNGEAVVIDRNITHQDIARFIGTSRETVTRIINKLKDKGLLEIKREKIILKDINKW
>Mature_218_residues
SEISYRSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIKVSYDGKEKILEVMGPGDFFGE
MAIIDSKGRSATARVIRDSSLLVVGNQEFLNLVREYPFIALKIIGELSRRLRQANQDIESLAFLDVETRLKKFFRRMTGE
IRDNGEAVVIDRNITHQDIARFIGTSRETVTRIINKLKDKGLLEIKREKIILKDINKW

Specific function: This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of one or more genes involved in the induction of competence [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=199, Percent_Identity=27.1356783919598, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25216; Mature: 25084

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEISYRSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCEEEEE
VSYDGKEKILEVMGPGDFFGEMAIIDSKGRSATARVIRDSSLLVVGNQEFLNLVREYPFI
EECCCHHHHHHHCCCCCHHCCEEEEECCCCCHHHHEEECCCEEEECCHHHHHHHHHCCHH
ALKIIGELSRRLRQANQDIESLAFLDVETRLKKFFRRMTGEIRDNGEAVVIDRNITHQDI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCCHHHH
ARFIGTSRETVTRIINKLKDKGLLEIKREKIILKDINKW
HHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEISYRSIPLFSGLNDEQLDLLKSITNKRRYKAGEILFFEGDKPDAFYIVVEGEIQIIK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCEEEEE
VSYDGKEKILEVMGPGDFFGEMAIIDSKGRSATARVIRDSSLLVVGNQEFLNLVREYPFI
EECCCHHHHHHHCCCCCHHCCEEEEECCCCCHHHHEEECCCEEEECCHHHHHHHHHCCHH
ALKIIGELSRRLRQANQDIESLAFLDVETRLKKFFRRMTGEIRDNGEAVVIDRNITHQDI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCCHHHH
ARFIGTSRETVTRIINKLKDKGLLEIKREKIILKDINKW
HHHHCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1542653; 7542800 [H]