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The map label for this gene is rho [H]

Identifier: 220932637

GI number: 220932637

Start: 1924590

End: 1925846

Strand: Reverse

Name: rho [H]

Synonym: Hore_18010

Alternate gene names: 220932637

Gene position: 1925846-1924590 (Counterclockwise)

Preceding gene: 220932638

Following gene: 220932636

Centisome position: 74.7

GC content: 42.32

Gene sequence:

>1257_bases
TTGCTTAATATCAGTGAACTTGAGAAAAAAACTATTACTGAGTTACATAAACTGGCTAAAGAGCTCGATGTTACCGGATA
TACTCATATGAGAAAAAAAGACTTAATCTTTGCTATTTTAAAGAGAGAAACGGAGAAGGGGGGGCATATTTTTGCTGAAG
GGGTTCTCGAGATTGTTAATGGTGAAGGCTATGGTTTTTTAAGGCCTTCTAAATATGTTCCCTCCAGTGATGATATCTAT
ATATCGGCTTCCCAGATCAGGAGGTTTGATTTGAGAACTGGTGATGTAGTATCAGGACAGGTACGGGAGCCTAAAGAGGG
AGAGAGGTATTTTGCCCTGCTCAGGATAGAGGCCGTCAATTTTCAGGATCCAGAGAGGGCCAGGGACAGGGCTTATTTTG
AAGACCTGACTCCCCTTTATCCTGTGGAAAGGTTAAAACTGGAATATCATCCCAATGAAATTTCTACCCGATTGATAGAT
CTGGTGGCTCCAATTGGAAAGGGGCAGCGGGGGTTAATAGTATCCCCACCGAAGGCCGGAAAAACGGTTCTATTAAAAAA
GATAGCCAATAGTATTACCCATAATTACCCTGAAGCCAGGTTGATGATTTTATTAATAGATGAGAGGCCTGAAGAGGTTA
CTGATATGAAAAGGTCAGTTGATGCTGAGGTAATCAGTTCTACTTTTGATGAACCACCGGAAAACCACCTTCAGGTGGCT
GAACTGGTTTTAAAGAAGGCTAAACGCCTGGTAGAACACAAATATGATGTAATAATCCTCCTTGATAGTATAACCCGACT
GGCCCGCGCAGCCAATGTAACCATACCACCAAGCGGCCGTACTCTCTCCGGTGGATTAGACCCCAATGCCATGCATTTCC
CAAAAAGGTTTTTTGGGGCAGGGCGGAATATTGAAGAAGGTGGCAGTTTAACTATTCTGGCTACAGCCCTGGTAGATACC
GGTAGCAGGATGGATGATGTTATTTATGAAGAGTTTAAGGGAACGGGAAATATGGAAATACATTTAAATCGTCACCTGGC
AGAACAGAGGCTATTCCCGGCTATTGATATCAAGAAGTCAGGAACGAGAAAGGAAGAACTCCTCCTTGATAAAAAAGAAC
TGGATACTATGTGGAAGTTGCGTAAAGGGATTGCAAACACCAGTACCACAGAAATCATGGAGTCTTTTATAAAACAGCTT
CATAATACCAGAACAAACAGGGATTTATTGGTAAGCCTCAACAGGGTATTTGGTTAA

Upstream 100 bases:

>100_bases
TTTATATATTACAAAATTTTTACTTAATTTGAGTTTTACTTAATTTGACTATAGGTTTTCTAATTTTCCAGTGTTATCGG
TTAAGAAAGGTGGGTTTGTA

Downstream 100 bases:

>100_bases
TGCCCATCGGTTGCAGAGAGAATTTACGTGTGTTATAATATAAAAGTTGAAAAAGGAGAAAGAGGTGATATCATGAAAAA
AGGTATTCATCCCGAGATTA

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLNISELEKKTITELHKLAKELDVTGYTHMRKKDLIFAILKRETEKGGHIFAEGVLEIVNGEGYGFLRPSKYVPSSDDIY
ISASQIRRFDLRTGDVVSGQVREPKEGERYFALLRIEAVNFQDPERARDRAYFEDLTPLYPVERLKLEYHPNEISTRLID
LVAPIGKGQRGLIVSPPKAGKTVLLKKIANSITHNYPEARLMILLIDERPEEVTDMKRSVDAEVISSTFDEPPENHLQVA
ELVLKKAKRLVEHKYDVIILLDSITRLARAANVTIPPSGRTLSGGLDPNAMHFPKRFFGAGRNIEEGGSLTILATALVDT
GSRMDDVIYEEFKGTGNMEIHLNRHLAEQRLFPAIDIKKSGTRKEELLLDKKELDTMWKLRKGIANTSTTEIMESFIKQL
HNTRTNRDLLVSLNRVFG

Sequences:

>Translated_418_residues
MLNISELEKKTITELHKLAKELDVTGYTHMRKKDLIFAILKRETEKGGHIFAEGVLEIVNGEGYGFLRPSKYVPSSDDIY
ISASQIRRFDLRTGDVVSGQVREPKEGERYFALLRIEAVNFQDPERARDRAYFEDLTPLYPVERLKLEYHPNEISTRLID
LVAPIGKGQRGLIVSPPKAGKTVLLKKIANSITHNYPEARLMILLIDERPEEVTDMKRSVDAEVISSTFDEPPENHLQVA
ELVLKKAKRLVEHKYDVIILLDSITRLARAANVTIPPSGRTLSGGLDPNAMHFPKRFFGAGRNIEEGGSLTILATALVDT
GSRMDDVIYEEFKGTGNMEIHLNRHLAEQRLFPAIDIKKSGTRKEELLLDKKELDTMWKLRKGIANTSTTEIMESFIKQL
HNTRTNRDLLVSLNRVFG
>Mature_418_residues
MLNISELEKKTITELHKLAKELDVTGYTHMRKKDLIFAILKRETEKGGHIFAEGVLEIVNGEGYGFLRPSKYVPSSDDIY
ISASQIRRFDLRTGDVVSGQVREPKEGERYFALLRIEAVNFQDPERARDRAYFEDLTPLYPVERLKLEYHPNEISTRLID
LVAPIGKGQRGLIVSPPKAGKTVLLKKIANSITHNYPEARLMILLIDERPEEVTDMKRSVDAEVISSTFDEPPENHLQVA
ELVLKKAKRLVEHKYDVIILLDSITRLARAANVTIPPSGRTLSGGLDPNAMHFPKRFFGAGRNIEEGGSLTILATALVDT
GSRMDDVIYEEFKGTGNMEIHLNRHLAEQRLFPAIDIKKSGTRKEELLLDKKELDTMWKLRKGIANTSTTEIMESFIKQL
HNTRTNRDLLVSLNRVFG

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=419, Percent_Identity=58.9498806682578, Blast_Score=508, Evalue=1e-145,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 47398; Mature: 47398

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNISELEKKTITELHKLAKELDVTGYTHMRKKDLIFAILKRETEKGGHIFAEGVLEIVN
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHC
GEGYGFLRPSKYVPSSDDIYISASQIRRFDLRTGDVVSGQVREPKEGERYFALLRIEAVN
CCCCEECCCCCCCCCCCCEEEEHHHHHEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC
FQDPERARDRAYFEDLTPLYPVERLKLEYHPNEISTRLIDLVAPIGKGQRGLIVSPPKAG
CCCHHHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCC
KTVLLKKIANSITHNYPEARLMILLIDERPEEVTDMKRSVDAEVISSTFDEPPENHLQVA
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ELVLKKAKRLVEHKYDVIILLDSITRLARAANVTIPPSGRTLSGGLDPNAMHFPKRFFGA
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCEECCCCCEECCCCCCCHHHCCHHHHCC
GRNIEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMEIHLNRHLAEQRLFPAIDIKKS
CCCCCCCCCEEEEEEEHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEECCCC
GTRKEELLLDKKELDTMWKLRKGIANTSTTEIMESFIKQLHNTRTNRDLLVSLNRVFG
CCCHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEHHHCC
>Mature Secondary Structure
MLNISELEKKTITELHKLAKELDVTGYTHMRKKDLIFAILKRETEKGGHIFAEGVLEIVN
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHC
GEGYGFLRPSKYVPSSDDIYISASQIRRFDLRTGDVVSGQVREPKEGERYFALLRIEAVN
CCCCEECCCCCCCCCCCCEEEEHHHHHEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC
FQDPERARDRAYFEDLTPLYPVERLKLEYHPNEISTRLIDLVAPIGKGQRGLIVSPPKAG
CCCHHHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCC
KTVLLKKIANSITHNYPEARLMILLIDERPEEVTDMKRSVDAEVISSTFDEPPENHLQVA
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ELVLKKAKRLVEHKYDVIILLDSITRLARAANVTIPPSGRTLSGGLDPNAMHFPKRFFGA
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCEECCCCCEECCCCCCCHHHCCHHHHCC
GRNIEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMEIHLNRHLAEQRLFPAIDIKKS
CCCCCCCCCEEEEEEEHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEECCCC
GTRKEELLLDKKELDTMWKLRKGIANTSTTEIMESFIKQLHNTRTNRDLLVSLNRVFG
CCCHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]