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The map label for this gene is 220932531

Identifier: 220932531

GI number: 220932531

Start: 1814005

End: 1815000

Strand: Reverse

Name: 220932531

Synonym: Hore_16950

Alternate gene names: NA

Gene position: 1815000-1814005 (Counterclockwise)

Preceding gene: 220932532

Following gene: 220932530

Centisome position: 70.4

GC content: 35.24

Gene sequence:

>996_bases
ATGGGTGTCTTTGTTATTGCTGAAGCTGGTGTAAATCATAATGGTGACATTAAGTTAGCTAAAGAATTAATAGACAAAGC
TGTATGGGCCGGGGCTGATGCAATAAAATTTCAGACCTTCAGGGCAGATAAACTTGCCTCCAAAATAGCTAGAAAAGCAG
ACTATCAAAAAGAAATGGTAGGGAAAGATGAGTCTCAATATACAATGTTAAAAAAATTAGAGTTTACTGTAAATGATTTT
AGAGCACTGAAGGAATACTGTGACAGGAAAAATATCATATTTATGTCTTCACCCTTTGATTTAGAGAGTATTGACTTATT
AGCTAATTTGGGGATGGAAATCTGGAAGATACCTTCTGGAGAAATAACTAACCTTCCTTACTTAAGAAAGATCGGGCACC
TCAAAAAGAAAGTTATTATGTCTACTGGAATGTCCAATTTATCAGAGATAGAAGTTGCCCTGGATGTTCTCAAAGACCAG
GGTGTAAATGATATAACAGTCTTACACTGTAATACAGAATATCCAACCCCTATAGAAGACGTTAATTTAAAGGCAATGCA
AACTATACAAAATGCATTTAAAGTAAAAGTAGGTTATTCTGATCACACCAGGGGGATTGAAGTTCCTATTGCAGCAGTGG
CCTTAGGGGCTGAGGTAATTGAAAAACACTTTACTTTGGATAGGGATATGGAGGGCCCTGATCATAAAGCTAGCCTGGAG
CCAGAAGAACTTAAAATAATGATAGAATTTATAAGGAATATTGAGAAAGCTCTAGGGGATGGTATTAAAAAACCTTCTAA
ATCTGAAATTAAAAATAAGGATATTGTTAGGAAAAGTATTGTTGCTGCTCACAGCATTAGAAAAGGAGAAAGATTTACTG
AAGGTAATTTAACAGTTAAGAGACCAGGGAATGGTATAAGTCCCATGTATTGGGATCAAATTATTGGGAAAGTCGCTAAA
AGAGATTATAAAAAGGATGAGTTGATTGAGTTATGA

Upstream 100 bases:

>100_bases
CAATTGGCAGTGACACTATAATTGGAGCTGGTAGTGTAGTAGTTAACGACATTGGTGATAATAAAAAAGCATTTGGAGTC
CCCTGTAAGGAGAGATAAAA

Downstream 100 bases:

>100_bases
TAAAAAAGAAAGTATGTGTTGTTACTGGAACAAGAGCTGAATATGGCCTTTTAAGACCATTAATAAAAAGAATTAATGAA
TCAAATCTGCTTGAATTACA

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MGVFVIAEAGVNHNGDIKLAKELIDKAVWAGADAIKFQTFRADKLASKIARKADYQKEMVGKDESQYTMLKKLEFTVNDF
RALKEYCDRKNIIFMSSPFDLESIDLLANLGMEIWKIPSGEITNLPYLRKIGHLKKKVIMSTGMSNLSEIEVALDVLKDQ
GVNDITVLHCNTEYPTPIEDVNLKAMQTIQNAFKVKVGYSDHTRGIEVPIAAVALGAEVIEKHFTLDRDMEGPDHKASLE
PEELKIMIEFIRNIEKALGDGIKKPSKSEIKNKDIVRKSIVAAHSIRKGERFTEGNLTVKRPGNGISPMYWDQIIGKVAK
RDYKKDELIEL

Sequences:

>Translated_331_residues
MGVFVIAEAGVNHNGDIKLAKELIDKAVWAGADAIKFQTFRADKLASKIARKADYQKEMVGKDESQYTMLKKLEFTVNDF
RALKEYCDRKNIIFMSSPFDLESIDLLANLGMEIWKIPSGEITNLPYLRKIGHLKKKVIMSTGMSNLSEIEVALDVLKDQ
GVNDITVLHCNTEYPTPIEDVNLKAMQTIQNAFKVKVGYSDHTRGIEVPIAAVALGAEVIEKHFTLDRDMEGPDHKASLE
PEELKIMIEFIRNIEKALGDGIKKPSKSEIKNKDIVRKSIVAAHSIRKGERFTEGNLTVKRPGNGISPMYWDQIIGKVAK
RDYKKDELIEL
>Mature_330_residues
GVFVIAEAGVNHNGDIKLAKELIDKAVWAGADAIKFQTFRADKLASKIARKADYQKEMVGKDESQYTMLKKLEFTVNDFR
ALKEYCDRKNIIFMSSPFDLESIDLLANLGMEIWKIPSGEITNLPYLRKIGHLKKKVIMSTGMSNLSEIEVALDVLKDQG
VNDITVLHCNTEYPTPIEDVNLKAMQTIQNAFKVKVGYSDHTRGIEVPIAAVALGAEVIEKHFTLDRDMEGPDHKASLEP
EELKIMIEFIRNIEKALGDGIKKPSKSEIKNKDIVRKSIVAAHSIRKGERFTEGNLTVKRPGNGISPMYWDQIIGKVAKR
DYKKDELIEL

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=300, Percent_Identity=35.6666666666667, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI21357081, Length=357, Percent_Identity=31.3725490196078, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37263; Mature: 37131

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVFVIAEAGVNHNGDIKLAKELIDKAVWAGADAIKFQTFRADKLASKIARKADYQKEMV
CCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
GKDESQYTMLKKLEFTVNDFRALKEYCDRKNIIFMSSPFDLESIDLLANLGMEIWKIPSG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCHHEEECCCC
EITNLPYLRKIGHLKKKVIMSTGMSNLSEIEVALDVLKDQGVNDITVLHCNTEYPTPIED
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
VNLKAMQTIQNAFKVKVGYSDHTRGIEVPIAAVALGAEVIEKHFTLDRDMEGPDHKASLE
CCHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEELKIMIEFIRNIEKALGDGIKKPSKSEIKNKDIVRKSIVAAHSIRKGERFTEGNLTVK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
RPGNGISPMYWDQIIGKVAKRDYKKDELIEL
CCCCCCCHHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
GVFVIAEAGVNHNGDIKLAKELIDKAVWAGADAIKFQTFRADKLASKIARKADYQKEMV
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHH
GKDESQYTMLKKLEFTVNDFRALKEYCDRKNIIFMSSPFDLESIDLLANLGMEIWKIPSG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCHHEEECCCC
EITNLPYLRKIGHLKKKVIMSTGMSNLSEIEVALDVLKDQGVNDITVLHCNTEYPTPIED
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
VNLKAMQTIQNAFKVKVGYSDHTRGIEVPIAAVALGAEVIEKHFTLDRDMEGPDHKASLE
CCHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEELKIMIEFIRNIEKALGDGIKKPSKSEIKNKDIVRKSIVAAHSIRKGERFTEGNLTVK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
RPGNGISPMYWDQIIGKVAKRDYKKDELIEL
CCCCCCCHHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]