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The map label for this gene is hldE [H]

Identifier: 220932487

GI number: 220932487

Start: 1774550

End: 1775545

Strand: Reverse

Name: hldE [H]

Synonym: Hore_16505

Alternate gene names: 220932487

Gene position: 1775545-1774550 (Counterclockwise)

Preceding gene: 220932488

Following gene: 220932486

Centisome position: 68.87

GC content: 42.57

Gene sequence:

>996_bases
ATGAAACAACTTACAGGCTATATTCAGCAATTTAATAATATAAAAATAATGGTTGTTGGTGAATTAATCGCTGATGAATT
TATTACAGGAGAACCTGAGAGAATATCAAGGGAGGCACCTGTTCTTATCCTGAGACACCATAATCAGCAAATATTACCGG
GAGGTGGTGCCAATGCCGCCCATAATATATCCAGTCTCGGGGGAAGAGTGAATCTGGTCGGGATAATAGGACCAGATCAA
CCTGGAAATAAATTATGCCGTTATCTGGAAGAACACGGGGTGGATGTAAACGGTGTTGTGGTTGCTGAGGACAGGCCTAC
CTGTGTTAAGACCAGGATACTGGCCGGTGGTGGTGGTATTGTAAAACAGCAGGTGGTTAGAATTGATCGCCTGGATAATT
CCCCCATTGACCGGGACCTGGAAGAAAGAATAATATTAAATGTCAGGGACAATATTAAAAATGTTGATGGGATTTTAATA
TCTGATTATGGAAATGGTTTGTTTACTGAAAGGGTTAAACGGGAAATTATTAAAGCAGGGAGAAGTAGAGGAAAATTTAT
TGCAGTTGATACCCGTTATAACCTTCTTGATTACCAGGGGATTACGATAGCTACCCCAAATCTTGAGGAAGCCAGTTATG
CCGTTGGATGGGAGATTAAGACCAGAGATGAAGTTATTAAAGCCGGTAAAGAAATCATTGGTCACATGGATATGGAATAC
TTACTTATAACCCAGGGTGGAGATGGGATGACCCTTTTTAATAAGGAAGGGGAATTCCAGCATATTCCAGCTGTCAACTA
TACCGAGGTCTATGATGTAACCGGGGCCGGAGATACTGTGGTAGCAACCCTTTCACTGGCCCTGGGTGCCGGGGCAACCA
TGGAAGAAGCCATGGATCTGGCCAATACTGCTGCCGGTATTGTGGTCAGGAAATCAGGTGTGGCTACAGTAAAACCAGGA
GAGTTAATGGAAGAAGTGATAAAAAATGAGAAATAA

Upstream 100 bases:

>100_bases
CCTGATACTTTCCTGACTCTCGGGGTCGGGAATTCCTACTGGGACCGTAATGATATCAACTTAAATATTGGAATAAAAGT
TGATTTATAGGAGGAAACTA

Downstream 100 bases:

>100_bases
AATTCAGGATATAAATTCTTTGCAAACGATTGTTCAAACCTTAAAACAGGGAGGGAAAACCCTGGTTTTTACCAATGGTT
GTTTTGACCTCATTCATGTG

Product: Rfae domain I

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKQLTGYIQQFNNIKIMVVGELIADEFITGEPERISREAPVLILRHHNQQILPGGGANAAHNISSLGGRVNLVGIIGPDQ
PGNKLCRYLEEHGVDVNGVVVAEDRPTCVKTRILAGGGGIVKQQVVRIDRLDNSPIDRDLEERIILNVRDNIKNVDGILI
SDYGNGLFTERVKREIIKAGRSRGKFIAVDTRYNLLDYQGITIATPNLEEASYAVGWEIKTRDEVIKAGKEIIGHMDMEY
LLITQGGDGMTLFNKEGEFQHIPAVNYTEVYDVTGAGDTVVATLSLALGAGATMEEAMDLANTAAGIVVRKSGVATVKPG
ELMEEVIKNEK

Sequences:

>Translated_331_residues
MKQLTGYIQQFNNIKIMVVGELIADEFITGEPERISREAPVLILRHHNQQILPGGGANAAHNISSLGGRVNLVGIIGPDQ
PGNKLCRYLEEHGVDVNGVVVAEDRPTCVKTRILAGGGGIVKQQVVRIDRLDNSPIDRDLEERIILNVRDNIKNVDGILI
SDYGNGLFTERVKREIIKAGRSRGKFIAVDTRYNLLDYQGITIATPNLEEASYAVGWEIKTRDEVIKAGKEIIGHMDMEY
LLITQGGDGMTLFNKEGEFQHIPAVNYTEVYDVTGAGDTVVATLSLALGAGATMEEAMDLANTAAGIVVRKSGVATVKPG
ELMEEVIKNEK
>Mature_331_residues
MKQLTGYIQQFNNIKIMVVGELIADEFITGEPERISREAPVLILRHHNQQILPGGGANAAHNISSLGGRVNLVGIIGPDQ
PGNKLCRYLEEHGVDVNGVVVAEDRPTCVKTRILAGGGGIVKQQVVRIDRLDNSPIDRDLEERIILNVRDNIKNVDGILI
SDYGNGLFTERVKREIIKAGRSRGKFIAVDTRYNLLDYQGITIATPNLEEASYAVGWEIKTRDEVIKAGKEIIGHMDMEY
LLITQGGDGMTLFNKEGEFQHIPAVNYTEVYDVTGAGDTVVATLSLALGAGATMEEAMDLANTAAGIVVRKSGVATVKPG
ELMEEVIKNEK

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=322, Percent_Identity=35.4037267080745, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 36074; Mature: 36074

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLTGYIQQFNNIKIMVVGELIADEFITGEPERISREAPVLILRHHNQQILPGGGANAA
CCHHHHHHHHHCCEEEEEEEHHHHHHHCCCCHHHHCCCCCEEEEEECCCEECCCCCCCHH
HNISSLGGRVNLVGIIGPDQPGNKLCRYLEEHGVDVNGVVVAEDRPTCVKTRILAGGGGI
HHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCH
VKQQVVRIDRLDNSPIDRDLEERIILNVRDNIKNVDGILISDYGNGLFTERVKREIIKAG
HHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHC
RSRGKFIAVDTRYNLLDYQGITIATPNLEEASYAVGWEIKTRDEVIKAGKEIIGHMDMEY
CCCCCEEEEECCCCEEEECCEEEECCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCEE
LLITQGGDGMTLFNKEGEFQHIPAVNYTEVYDVTGAGDTVVATLSLALGAGATMEEAMDL
EEEEECCCCEEEECCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHH
ANTAAGIVVRKSGVATVKPGELMEEVIKNEK
HHHHCEEEEEECCCCEECCHHHHHHHHCCCC
>Mature Secondary Structure
MKQLTGYIQQFNNIKIMVVGELIADEFITGEPERISREAPVLILRHHNQQILPGGGANAA
CCHHHHHHHHHCCEEEEEEEHHHHHHHCCCCHHHHCCCCCEEEEEECCCEECCCCCCCHH
HNISSLGGRVNLVGIIGPDQPGNKLCRYLEEHGVDVNGVVVAEDRPTCVKTRILAGGGGI
HHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCH
VKQQVVRIDRLDNSPIDRDLEERIILNVRDNIKNVDGILISDYGNGLFTERVKREIIKAG
HHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHC
RSRGKFIAVDTRYNLLDYQGITIATPNLEEASYAVGWEIKTRDEVIKAGKEIIGHMDMEY
CCCCCEEEEECCCCEEEECCEEEECCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCEE
LLITQGGDGMTLFNKEGEFQHIPAVNYTEVYDVTGAGDTVVATLSLALGAGATMEEAMDL
EEEEECCCCEEEECCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHH
ANTAAGIVVRKSGVATVKPGELMEEVIKNEK
HHHHCEEEEEECCCCEECCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA