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The map label for this gene is sdaAA [H]

Identifier: 220932469

GI number: 220932469

Start: 1755447

End: 1756313

Strand: Reverse

Name: sdaAA [H]

Synonym: Hore_16330

Alternate gene names: 220932469

Gene position: 1756313-1755447 (Counterclockwise)

Preceding gene: 220932470

Following gene: 220932468

Centisome position: 68.12

GC content: 48.21

Gene sequence:

>867_bases
ATGGAGTATTCTACTATCAAAGACTTAATAGACCTGGCTTTTGATCTTGATACCACCATTTCGGAGGTTGTCATCAGGAC
GGAAATGGAGGATTCAGAGAGATCAAAGATATCTATTGAAAAACAGATGATGCATAACCTTGAGGTTATGAAAAACTCCA
TCAATGAAGGACGAAAAGGTATTATTAGATCAACGAGTGGAGTTATTGGCGGTGAATCTCACCGGTTAGTGGGGTACAGT
GGCCCCCTGAGCGGGGGGTTATATCATGAAGTTATTATTAATGCCCTGGCAGTTTCGGAAGTTAATGCCGGTATGGGCAA
GATTGTGGCCTGCCCCACCGCCGGTTCCAGTGGTGTTATTCCTGCGGTAGTGATATCGGTCGGCCAGGAATATGACCTTT
CTGATAAAAAAATATGTAAAAGCCTCTTTACTGCAGCAGGTCTGGGGGAAATAGTTGCTAAAAAAGCTACCCTGGCCGGT
GCAGCCGGTGGCTGTCAGGCCGAGTGTGGTGTGGCAGCAGCCATGGCAGCCGGGGCTGTTGTCGAACTACTGGGTGGAAA
TCCGGAAATGGTCGGCCATGGGTTTGCTCTGGCCCTGAAAAACTTACTGGGCCTTGCCTGTGATCCTGTGGCTGGACTGG
TTGAAGTTCCCTGTGTTAAAAGAAATGGTTTTGCCGCTACCCATGCCCTTACTGCGGCCAGTATGGCCCTGGCCGGTATT
GAAAGTGTTATCCCTCCTGATGAAGTAATTGAAGCCATGATTGATATCGGTAATCTTTTACCCCAGTTCCTTAAGGAAAC
ATCACAGGCCGGGCTGGCTACAACCCCGACCGGGCTCAGAATTAAAAAAAGAATTGACAGGAAGTAG

Upstream 100 bases:

>100_bases
TGTGGATGAGGATATTATTGATCATTTACAGGGGATGAAAGATATCTTAAAAGTAAGGTATATACCCCCTTTATAAAACC
CTCTTGAAAGGTGGTCTATA

Downstream 100 bases:

>100_bases
GATTCAGGTTATAATTAAAAAAATACTGCCTTATGGTAGTATTTTTTTACCCGATTTTAGTTTCATATAACGAAAAATCA
TTTTACATAATGAAAAAAGG

Product: L-serine ammonia-lyase subunit alpha

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MEYSTIKDLIDLAFDLDTTISEVVIRTEMEDSERSKISIEKQMMHNLEVMKNSINEGRKGIIRSTSGVIGGESHRLVGYS
GPLSGGLYHEVIINALAVSEVNAGMGKIVACPTAGSSGVIPAVVISVGQEYDLSDKKICKSLFTAAGLGEIVAKKATLAG
AAGGCQAECGVAAAMAAGAVVELLGGNPEMVGHGFALALKNLLGLACDPVAGLVEVPCVKRNGFAATHALTAASMALAGI
ESVIPPDEVIEAMIDIGNLLPQFLKETSQAGLATTPTGLRIKKRIDRK

Sequences:

>Translated_288_residues
MEYSTIKDLIDLAFDLDTTISEVVIRTEMEDSERSKISIEKQMMHNLEVMKNSINEGRKGIIRSTSGVIGGESHRLVGYS
GPLSGGLYHEVIINALAVSEVNAGMGKIVACPTAGSSGVIPAVVISVGQEYDLSDKKICKSLFTAAGLGEIVAKKATLAG
AAGGCQAECGVAAAMAAGAVVELLGGNPEMVGHGFALALKNLLGLACDPVAGLVEVPCVKRNGFAATHALTAASMALAGI
ESVIPPDEVIEAMIDIGNLLPQFLKETSQAGLATTPTGLRIKKRIDRK
>Mature_288_residues
MEYSTIKDLIDLAFDLDTTISEVVIRTEMEDSERSKISIEKQMMHNLEVMKNSINEGRKGIIRSTSGVIGGESHRLVGYS
GPLSGGLYHEVIINALAVSEVNAGMGKIVACPTAGSSGVIPAVVISVGQEYDLSDKKICKSLFTAAGLGEIVAKKATLAG
AAGGCQAECGVAAAMAAGAVVELLGGNPEMVGHGFALALKNLLGLACDPVAGLVEVPCVKRNGFAATHALTAASMALAGI
ESVIPPDEVIEAMIDIGNLLPQFLKETSQAGLATTPTGLRIKKRIDRK

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=285, Percent_Identity=34.7368421052632, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1788116, Length=276, Percent_Identity=35.5072463768116, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI48994925, Length=181, Percent_Identity=40.8839779005525, Blast_Score=134, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 29845; Mature: 29845

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYSTIKDLIDLAFDLDTTISEVVIRTEMEDSERSKISIEKQMMHNLEVMKNSINEGRKG
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIRSTSGVIGGESHRLVGYSGPLSGGLYHEVIINALAVSEVNAGMGKIVACPTAGSSGVI
HHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCH
PAVVISVGQEYDLSDKKICKSLFTAAGLGEIVAKKATLAGAAGGCQAECGVAAAMAAGAV
HHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VELLGGNPEMVGHGFALALKNLLGLACDPVAGLVEVPCVKRNGFAATHALTAASMALAGI
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ESVIPPDEVIEAMIDIGNLLPQFLKETSQAGLATTPTGLRIKKRIDRK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MEYSTIKDLIDLAFDLDTTISEVVIRTEMEDSERSKISIEKQMMHNLEVMKNSINEGRKG
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIRSTSGVIGGESHRLVGYSGPLSGGLYHEVIINALAVSEVNAGMGKIVACPTAGSSGVI
HHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCH
PAVVISVGQEYDLSDKKICKSLFTAAGLGEIVAKKATLAGAAGGCQAECGVAAAMAAGAV
HHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VELLGGNPEMVGHGFALALKNLLGLACDPVAGLVEVPCVKRNGFAATHALTAASMALAGI
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ESVIPPDEVIEAMIDIGNLLPQFLKETSQAGLATTPTGLRIKKRIDRK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]