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The map label for this gene is mpg1 [H]

Identifier: 220932434

GI number: 220932434

Start: 1711814

End: 1714276

Strand: Reverse

Name: mpg1 [H]

Synonym: Hore_15980

Alternate gene names: 220932434

Gene position: 1714276-1711814 (Counterclockwise)

Preceding gene: 220932435

Following gene: 220932430

Centisome position: 66.49

GC content: 40.72

Gene sequence:

>2463_bases
TTGAAAGGTGTAATTATGGCCGGCGGGCAGGGTTCGAGGTTACGTCCGCTAACATGTAACCTACCCAAGCCCATGGTTCC
TGTGATGAATTATCCGGTTATGGAATATATCATAACCCTTTTAAAAAATTATGGCATAAAAGATATTGCTGTCACAACTT
ATTATCTTCCGAACAAAATTGAGAGTTATTTTGGTGATGGTAGTAAATGGGGGGTAAACCTCCATTATTTTGTTGAAAAA
GAACCCCTGGGGACAGCCGGAAGTGTTGCTAATGCCAGGGATTTTTTAGATGAACCTTTTATGGTTATAAGTGGTGACGC
CATTACAGATTTTGACCTGGGAGAAGCAATTTCCTTTCATCAGGAAAAGGGGGCTTCAGCTACTATAGTTCTGGCCAGGG
TTAAAACCCCACTGGATTATGGGGTGGTTATTACCGATGAAAGGGGTAGAATAGTCAGATTTTTGGAAAAACCAAACTGG
GGGCAGGTTTTCAGTGACACCGTCAATACCGGAATATATGTCCTGGAGCCCGAAATTTTTGATCTCTATGATAAGGGTAT
TAACTTTGATTTCAGTAAAGACCTGTTTCCTTTAATGCTTGAAAAAAACTGGAACTTATATGGAATTTCACTTAAAGGTT
ACTGGAATGATATTGGGAGTCTTGAAGAGTATATCAACACCAATTTTGATTTCTTTAAAGGAGAAATTGATTTACCGCTT
GAAGCCTGTTGTGTCCTGGATAACAATATCTGGCTTCAGGATGGGGTTGAAATAGATGAAACGGCTGAACTGGAAGGTCC
ACTCTTTATTGGGGAAGGGACCAGGATTGGTAAAGGGGCCCGGGTAGCAAATTCAATAATAGGACGTAACAATTATATTC
AACCCCATGCTTCCATTAAGAAAAGCATTCTCTGGGATAATAATTTTGTTGGTGCCAATGCTGAAATCAGGGGAGCAGTA
ATTACAGAAAACGTGGTAGTCAGGGAACGGGGTAGTATTTTTGACCTGGCTGCCGTCGGGGAAAAGGTAGTAATCGGTGA
AGAGAGCAAGGTTGCTCCCGGTATTAAAATCTGGCCTGAAAGGGAAATTGAGTCCAGAGTAGAGGTTAGAGACAATATCG
TCTGGAGGCCCCGGTGGCAGAAAAAACTATTTACCAATACCGGGGTTATAGGGGAAGGGAATATCGATATTACCCCTGAA
TTTGTAACCAGACTGGCGGTAGCATTTGCCTCGACTATAGATAGAAATAAAAGTATAACGGTAAGTTCAGATACATATGG
ACTGACCAGTGCATTAAAAAGGGCGGTTATTTCCGGGATTCAACTGGCAGGGCGAAATGTCCTGGAGCTCGGGGAGATTA
CTACAGCTGTAGCCAGATATGGGATTATTAATATGCAGGCAGGAGGCGGTATTCATATCCGGTTAAGTTATAATAATCCT
GAGAAAGTAGTTCTGGAGTTTATGAATGAAAAAGGGGTAAATTTACCGGCTCCGGACCAGAAAAGGGTTGAAAAAAAGTT
CTTTACAGAGGATTATAACAGAGCTCCTGTAAATGACATAGGTGATTATGCCCTGGTTCCAGAAATGGTAAATGAATATT
TATATGGCATTCTCGATACAGTTGATACTGAAGCCATTAAACGTAACTATTTCAGTGTGGTGATTGACTATGAATATGAT
AGTTTAAACCATCTCTTACCCCTGTTATTAAAAAGACTAAATTGTCAAATGTTATCTACCAGAAATTATTCCCGGACCGG
TCGACCTTTAAGCCTTCAAGAAAGGCTGGAAGCAAGAGATAAGGTTAGCAGGATATTGAATGAGAATGAGGCAGATCTGG
GGATTATTGTTGACCATAATGCTGAAAGATTAAATCTTGTTGCCGGAAATAAACAGGTACTGGACCCCTTCAAATACCAG
GTAATGCTTTCTTACCTGTTGTTAGAAAGGGGAGTCAAAAAATTATTTGTTCCCTTTAATTCTCCCAAGGTAATTGAAAA
TATAGCCGATGATTATGATGCCGATGTTGTTTATACTCCTCTGGCCCCCCAGGTTTCCATGGAAAAGTATATGGTTTATG
AACACAACCCATTTAAGTTTTATCCCTTTAATGATGCCATAGCTGCTCTGGTATTAATCCTGGAAAAAATGGCAGTGGAG
AATATATCTTTTGAGCAATTACTCAACCGCCTTCCCGAGTTTTACCTGGAAAGGGTTGAAATACCCTGTGAATGGCACGA
CAAGGGTCGGGTTATGAGGAGGCTGGCTGAAGAAGCCAGGGACAATACTGAACTGGTTGATGGTATTAAGTTTAACCATA
GAAACGGCTGGGCCCTGGTTATACCCGATAATGAGGAACCAGTCTTTCATATCTTTGCCGAAGGTCAGGATGAAGAAACA
GCCGAGAGTTTAACCGGTTTTTATATAGAAAAGGTAAAAAGGTTAATAGATAAGGATAATTAA

Upstream 100 bases:

>100_bases
AAGAAAGAACATATATTAAGAATGAAGAAGATTCACCGGTTTACAGATATCTGTTTAAAAGAAAGTTCAGTTAATCCAGG
TGTGAAAGGGGGATTACCTT

Downstream 100 bases:

>100_bases
TAAATAAGATATGGTTTTAACAATTTATTTTTATGGTAAAATATTAAATAAAAAATGGAGACGATTTCTATTAAAAAAAT
GGCCTGATGGAGCAGGCCAT

Product: phosphoglucomutase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 820; Mature: 820

Protein sequence:

>820_residues
MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIAVTTYYLPNKIESYFGDGSKWGVNLHYFVEK
EPLGTAGSVANARDFLDEPFMVISGDAITDFDLGEAISFHQEKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNW
GQVFSDTVNTGIYVLEPEIFDLYDKGINFDFSKDLFPLMLEKNWNLYGISLKGYWNDIGSLEEYINTNFDFFKGEIDLPL
EACCVLDNNIWLQDGVEIDETAELEGPLFIGEGTRIGKGARVANSIIGRNNYIQPHASIKKSILWDNNFVGANAEIRGAV
ITENVVVRERGSIFDLAAVGEKVVIGEESKVAPGIKIWPEREIESRVEVRDNIVWRPRWQKKLFTNTGVIGEGNIDITPE
FVTRLAVAFASTIDRNKSITVSSDTYGLTSALKRAVISGIQLAGRNVLELGEITTAVARYGIINMQAGGGIHIRLSYNNP
EKVVLEFMNEKGVNLPAPDQKRVEKKFFTEDYNRAPVNDIGDYALVPEMVNEYLYGILDTVDTEAIKRNYFSVVIDYEYD
SLNHLLPLLLKRLNCQMLSTRNYSRTGRPLSLQERLEARDKVSRILNENEADLGIIVDHNAERLNLVAGNKQVLDPFKYQ
VMLSYLLLERGVKKLFVPFNSPKVIENIADDYDADVVYTPLAPQVSMEKYMVYEHNPFKFYPFNDAIAALVLILEKMAVE
NISFEQLLNRLPEFYLERVEIPCEWHDKGRVMRRLAEEARDNTELVDGIKFNHRNGWALVIPDNEEPVFHIFAEGQDEET
AESLTGFYIEKVKRLIDKDN

Sequences:

>Translated_820_residues
MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIAVTTYYLPNKIESYFGDGSKWGVNLHYFVEK
EPLGTAGSVANARDFLDEPFMVISGDAITDFDLGEAISFHQEKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNW
GQVFSDTVNTGIYVLEPEIFDLYDKGINFDFSKDLFPLMLEKNWNLYGISLKGYWNDIGSLEEYINTNFDFFKGEIDLPL
EACCVLDNNIWLQDGVEIDETAELEGPLFIGEGTRIGKGARVANSIIGRNNYIQPHASIKKSILWDNNFVGANAEIRGAV
ITENVVVRERGSIFDLAAVGEKVVIGEESKVAPGIKIWPEREIESRVEVRDNIVWRPRWQKKLFTNTGVIGEGNIDITPE
FVTRLAVAFASTIDRNKSITVSSDTYGLTSALKRAVISGIQLAGRNVLELGEITTAVARYGIINMQAGGGIHIRLSYNNP
EKVVLEFMNEKGVNLPAPDQKRVEKKFFTEDYNRAPVNDIGDYALVPEMVNEYLYGILDTVDTEAIKRNYFSVVIDYEYD
SLNHLLPLLLKRLNCQMLSTRNYSRTGRPLSLQERLEARDKVSRILNENEADLGIIVDHNAERLNLVAGNKQVLDPFKYQ
VMLSYLLLERGVKKLFVPFNSPKVIENIADDYDADVVYTPLAPQVSMEKYMVYEHNPFKFYPFNDAIAALVLILEKMAVE
NISFEQLLNRLPEFYLERVEIPCEWHDKGRVMRRLAEEARDNTELVDGIKFNHRNGWALVIPDNEEPVFHIFAEGQDEET
AESLTGFYIEKVKRLIDKDN
>Mature_820_residues
MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIAVTTYYLPNKIESYFGDGSKWGVNLHYFVEK
EPLGTAGSVANARDFLDEPFMVISGDAITDFDLGEAISFHQEKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNW
GQVFSDTVNTGIYVLEPEIFDLYDKGINFDFSKDLFPLMLEKNWNLYGISLKGYWNDIGSLEEYINTNFDFFKGEIDLPL
EACCVLDNNIWLQDGVEIDETAELEGPLFIGEGTRIGKGARVANSIIGRNNYIQPHASIKKSILWDNNFVGANAEIRGAV
ITENVVVRERGSIFDLAAVGEKVVIGEESKVAPGIKIWPEREIESRVEVRDNIVWRPRWQKKLFTNTGVIGEGNIDITPE
FVTRLAVAFASTIDRNKSITVSSDTYGLTSALKRAVISGIQLAGRNVLELGEITTAVARYGIINMQAGGGIHIRLSYNNP
EKVVLEFMNEKGVNLPAPDQKRVEKKFFTEDYNRAPVNDIGDYALVPEMVNEYLYGILDTVDTEAIKRNYFSVVIDYEYD
SLNHLLPLLLKRLNCQMLSTRNYSRTGRPLSLQERLEARDKVSRILNENEADLGIIVDHNAERLNLVAGNKQVLDPFKYQ
VMLSYLLLERGVKKLFVPFNSPKVIENIADDYDADVVYTPLAPQVSMEKYMVYEHNPFKFYPFNDAIAALVLILEKMAVE
NISFEQLLNRLPEFYLERVEIPCEWHDKGRVMRRLAEEARDNTELVDGIKFNHRNGWALVIPDNEEPVFHIFAEGQDEET
AESLTGFYIEKVKRLIDKDN

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=373, Percent_Identity=30.2949061662198, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI11761619, Length=386, Percent_Identity=28.2383419689119, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI31881779, Length=425, Percent_Identity=25.1764705882353, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI45447090, Length=425, Percent_Identity=25.1764705882353, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI83267879, Length=399, Percent_Identity=21.0526315789474, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI1788351, Length=184, Percent_Identity=30.9782608695652, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1789837, Length=373, Percent_Identity=24.9329758713137, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790224, Length=185, Percent_Identity=31.3513513513514, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1788355, Length=222, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133931050, Length=379, Percent_Identity=29.8153034300792, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17509979, Length=341, Percent_Identity=23.7536656891496, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17509981, Length=331, Percent_Identity=22.9607250755287, Blast_Score=102, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320148, Length=339, Percent_Identity=32.4483775811209, Blast_Score=178, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6320417, Length=417, Percent_Identity=23.2613908872902, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21355443, Length=370, Percent_Identity=30.5405405405405, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24644084, Length=370, Percent_Identity=30.5405405405405, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24653912, Length=375, Percent_Identity=25.0666666666667, Blast_Score=115, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 92898; Mature: 92898

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIAVTTYYLPNKI
CCCEEEECCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHH
ESYFGDGSKWGVNLHYFVEKEPLGTAGSVANARDFLDEPFMVISGDAITDFDLGEAISFH
HHHCCCCCEECEEEEEEEECCCCCCCCCCCHHHHHHCCCCEEEECCEEECCCCCHHHHHH
QEKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNWGQVFSDTVNTGIYVLEPEIF
HHCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHCCCEEEECCHHH
DLYDKGINFDFSKDLFPLMLEKNWNLYGISLKGYWNDIGSLEEYINTNFDFFKGEIDLPL
HHHHCCCCCCCCCCCHHHHEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECEECCCH
EACCVLDNNIWLQDGVEIDETAELEGPLFIGEGTRIGKGARVANSIIGRNNYIQPHASIK
HEEEEECCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHH
KSILWDNNFVGANAEIRGAVITENVVVRERGSIFDLAAVGEKVVIGEESKVAPGIKIWPE
HHHEECCCEECCCCEEEEEEEECCEEEECCCCEEEHHHCCCEEEECCCCCCCCCCEECCC
REIESRVEVRDNIVWRPRWQKKLFTNTGVIGEGNIDITPEFVTRLAVAFASTIDRNKSIT
HHHHHHHHHHHCEEECCCHHHHHHHCCCEEECCCCEECHHHHHHHHHHHHHHHCCCCEEE
VSSDTYGLTSALKRAVISGIQLAGRNVLELGEITTAVARYGIINMQAGGGIHIRLSYNNP
EECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCC
EKVVLEFMNEKGVNLPAPDQKRVEKKFFTEDYNRAPVNDIGDYALVPEMVNEYLYGILDT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VDTEAIKRNYFSVVIDYEYDSLNHLLPLLLKRLNCQMLSTRNYSRTGRPLSLQERLEARD
HHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHH
KVSRILNENEADLGIIVDHNAERLNLVAGNKQVLDPFKYQVMLSYLLLERGVKKLFVPFN
HHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHCCCEEEECCC
SPKVIENIADDYDADVVYTPLAPQVSMEKYMVYEHNPFKFYPFNDAIAALVLILEKMAVE
CCHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHC
NISFEQLLNRLPEFYLERVEIPCEWHDKGRVMRRLAEEARDNTELVDGIKFNHRNGWALV
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEECCCCEEEE
IPDNEEPVFHIFAEGQDEETAESLTGFYIEKVKRLIDKDN
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIAVTTYYLPNKI
CCCEEEECCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHH
ESYFGDGSKWGVNLHYFVEKEPLGTAGSVANARDFLDEPFMVISGDAITDFDLGEAISFH
HHHCCCCCEECEEEEEEEECCCCCCCCCCCHHHHHHCCCCEEEECCEEECCCCCHHHHHH
QEKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNWGQVFSDTVNTGIYVLEPEIF
HHCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHCCCEEEECCHHH
DLYDKGINFDFSKDLFPLMLEKNWNLYGISLKGYWNDIGSLEEYINTNFDFFKGEIDLPL
HHHHCCCCCCCCCCCHHHHEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECEECCCH
EACCVLDNNIWLQDGVEIDETAELEGPLFIGEGTRIGKGARVANSIIGRNNYIQPHASIK
HEEEEECCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHH
KSILWDNNFVGANAEIRGAVITENVVVRERGSIFDLAAVGEKVVIGEESKVAPGIKIWPE
HHHEECCCEECCCCEEEEEEEECCEEEECCCCEEEHHHCCCEEEECCCCCCCCCCEECCC
REIESRVEVRDNIVWRPRWQKKLFTNTGVIGEGNIDITPEFVTRLAVAFASTIDRNKSIT
HHHHHHHHHHHCEEECCCHHHHHHHCCCEEECCCCEECHHHHHHHHHHHHHHHCCCCEEE
VSSDTYGLTSALKRAVISGIQLAGRNVLELGEITTAVARYGIINMQAGGGIHIRLSYNNP
EECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCC
EKVVLEFMNEKGVNLPAPDQKRVEKKFFTEDYNRAPVNDIGDYALVPEMVNEYLYGILDT
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VDTEAIKRNYFSVVIDYEYDSLNHLLPLLLKRLNCQMLSTRNYSRTGRPLSLQERLEARD
HHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHH
KVSRILNENEADLGIIVDHNAERLNLVAGNKQVLDPFKYQVMLSYLLLERGVKKLFVPFN
HHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHCCCEEEECCC
SPKVIENIADDYDADVVYTPLAPQVSMEKYMVYEHNPFKFYPFNDAIAALVLILEKMAVE
CCHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHC
NISFEQLLNRLPEFYLERVEIPCEWHDKGRVMRRLAEEARDNTELVDGIKFNHRNGWALV
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEECCCCEEEE
IPDNEEPVFHIFAEGQDEETAESLTGFYIEKVKRLIDKDN
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]