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The map label for this gene is gap [H]

Identifier: 220932419

GI number: 220932419

Start: 1695587

End: 1696600

Strand: Reverse

Name: gap [H]

Synonym: Hore_15830

Alternate gene names: 220932419

Gene position: 1696600-1695587 (Counterclockwise)

Preceding gene: 220932420

Following gene: 220932418

Centisome position: 65.81

GC content: 42.41

Gene sequence:

>1014_bases
ATGACTGTAAAAATTGGTATTAATGGTTTTGGAGCTATTGGACGTAGGGCTGTAAGGAGTGCTTATAAGAATCCCGAGGT
GGAGTTTGTAGCTGTTAATGACCTGACAGATGCTAAAACACTTGCTTATCTATTAAAATACGATACTAACTTTGGCCGTT
TAGAAGCAGAAGTTGACCACACCGAAAACAGTATTATCATCGACGGTAAGGAAATTAAAGTTCTTTCTGAAAAAGACCCT
GCTAACCTTCCCTGGGGTGATCTGGGGGTAGATGTTGTAATTGAATCTACCGGTCTTTTTACTGATGCTAATGATGCTAA
AAAACACCTGGAAGCCGGTGCTAAAAAAGTTATTATTTCTGCACCTGCCAAAAATGAAGACCTGACTATTGTACTGGGTG
TAAATGAAGATAAATATGACCCTGCTAACCACCATATTGTTTCCAATGCTTCCTGTACAACCAACTGTCTGGCTCCTGTT
GCCAAGGTACTTAATGATAAATTCGGTATTGAAAAAGGTTTAATGACCACTATTCACTCCTATACTTCTACCCAGAATAT
CCTGGATGGTCCTTATGCCTGGAAGAAAATGACCAGGGGTCGGGCTGCTGCTGAAAATATTGTACCGACCACAACCGGTG
CTGCCAAGGCCATCTCCCTGGTATTACCCGAACTGAAAGGTAAGTTAGACGGTATGGCTGTTCGTGTACCTACCCCAACC
GTATCCCTGGTTGACCTGGTAGTAACCCTCAAAAAGGATGTAACCGTTGAAGAAGTGAATGCTGCTATGAAAGAAGCCGC
TGAAGGTCCAATGAAAGGAATCCTGGGGTATAATGAATTACCCCTGGTATCCAGAGACTTCTTCGGTGATACCCGTTCTT
CCATCTTTGATGCAAACCATACCAGGGTTATGGAAGATGGAATGGTAAAAGTTCTTTCCTGGTATGATAATGAATACGGT
TATGCTAACAGGGTAGTAGATCTGGCCCTTTACATGGCTAAAAAAGGCCTGTAA

Upstream 100 bases:

>100_bases
TAAAGTGCATATTTCAACTAGTAAATAATCTTTAATTCATTTAATAAGGGAAGAATTAAAGATTAAATAAAACAACTAAT
TATAAGGAGGATGATTAAGT

Downstream 100 bases:

>100_bases
TTAATAGCATAATCAGATGTAAATCCAGAGGGGGTTGAAAGACCCCCTCTTAAATACGAATAGACCGGTTTGACTTATGT
AGTTTTATATATTACAGGTT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTVKIGINGFGAIGRRAVRSAYKNPEVEFVAVNDLTDAKTLAYLLKYDTNFGRLEAEVDHTENSIIIDGKEIKVLSEKDP
ANLPWGDLGVDVVIESTGLFTDANDAKKHLEAGAKKVIISAPAKNEDLTIVLGVNEDKYDPANHHIVSNASCTTNCLAPV
AKVLNDKFGIEKGLMTTIHSYTSTQNILDGPYAWKKMTRGRAAAENIVPTTTGAAKAISLVLPELKGKLDGMAVRVPTPT
VSLVDLVVTLKKDVTVEEVNAAMKEAAEGPMKGILGYNELPLVSRDFFGDTRSSIFDANHTRVMEDGMVKVLSWYDNEYG
YANRVVDLALYMAKKGL

Sequences:

>Translated_337_residues
MTVKIGINGFGAIGRRAVRSAYKNPEVEFVAVNDLTDAKTLAYLLKYDTNFGRLEAEVDHTENSIIIDGKEIKVLSEKDP
ANLPWGDLGVDVVIESTGLFTDANDAKKHLEAGAKKVIISAPAKNEDLTIVLGVNEDKYDPANHHIVSNASCTTNCLAPV
AKVLNDKFGIEKGLMTTIHSYTSTQNILDGPYAWKKMTRGRAAAENIVPTTTGAAKAISLVLPELKGKLDGMAVRVPTPT
VSLVDLVVTLKKDVTVEEVNAAMKEAAEGPMKGILGYNELPLVSRDFFGDTRSSIFDANHTRVMEDGMVKVLSWYDNEYG
YANRVVDLALYMAKKGL
>Mature_336_residues
TVKIGINGFGAIGRRAVRSAYKNPEVEFVAVNDLTDAKTLAYLLKYDTNFGRLEAEVDHTENSIIIDGKEIKVLSEKDPA
NLPWGDLGVDVVIESTGLFTDANDAKKHLEAGAKKVIISAPAKNEDLTIVLGVNEDKYDPANHHIVSNASCTTNCLAPVA
KVLNDKFGIEKGLMTTIHSYTSTQNILDGPYAWKKMTRGRAAAENIVPTTTGAAKAISLVLPELKGKLDGMAVRVPTPTV
SLVDLVVTLKKDVTVEEVNAAMKEAAEGPMKGILGYNELPLVSRDFFGDTRSSIFDANHTRVMEDGMVKVLSWYDNEYGY
ANRVVDLALYMAKKGL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=50, Blast_Score=344, Evalue=6e-95,
Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=50.5988023952096, Blast_Score=343, Evalue=1e-94,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=55.0898203592814, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1789295, Length=337, Percent_Identity=45.9940652818991, Blast_Score=306, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=52.9585798816568, Blast_Score=350, Evalue=6e-97,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=52.8189910979229, Blast_Score=348, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=52.3668639053254, Blast_Score=348, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=52.8189910979229, Blast_Score=348, Evalue=3e-96,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=55.5555555555556, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=55.2552552552552, Blast_Score=366, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=54.3543543543543, Blast_Score=361, Evalue=1e-101,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=52.8528528528528, Blast_Score=346, Evalue=2e-95,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=52.8528528528528, Blast_Score=346, Evalue=2e-95,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=51.9402985074627, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=51.9402985074627, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=48.1818181818182, Blast_Score=316, Evalue=1e-86,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36604; Mature: 36473

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKIGINGFGAIGRRAVRSAYKNPEVEFVAVNDLTDAKTLAYLLKYDTNFGRLEAEVDH
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECC
TENSIIIDGKEIKVLSEKDPANLPWGDLGVDVVIESTGLFTDANDAKKHLEAGAKKVIIS
CCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEEECCCCEECCHHHHHHHHCCCCEEEEE
APAKNEDLTIVLGVNEDKYDPANHHIVSNASCTTNCLAPVAKVLNDKFGIEKGLMTTIHS
CCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
YTSTQNILDGPYAWKKMTRGRAAAENIVPTTTGAAKAISLVLPELKGKLDGMAVRVPTPT
HHCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
VSLVDLVVTLKKDVTVEEVNAAMKEAAEGPMKGILGYNELPLVSRDFFGDTRSSIFDANH
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHCCCHHHHHCCCCC
TRVMEDGMVKVLSWYDNEYGYANRVVDLALYMAKKGL
CEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVKIGINGFGAIGRRAVRSAYKNPEVEFVAVNDLTDAKTLAYLLKYDTNFGRLEAEVDH
EEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECC
TENSIIIDGKEIKVLSEKDPANLPWGDLGVDVVIESTGLFTDANDAKKHLEAGAKKVIIS
CCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEEECCCCEECCHHHHHHHHCCCCEEEEE
APAKNEDLTIVLGVNEDKYDPANHHIVSNASCTTNCLAPVAKVLNDKFGIEKGLMTTIHS
CCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
YTSTQNILDGPYAWKKMTRGRAAAENIVPTTTGAAKAISLVLPELKGKLDGMAVRVPTPT
HHCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
VSLVDLVVTLKKDVTVEEVNAAMKEAAEGPMKGILGYNELPLVSRDFFGDTRSSIFDANH
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHCCCHHHHHCCCCC
TRVMEDGMVKVLSWYDNEYGYANRVVDLALYMAKKGL
CEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]