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The map label for this gene is pgk [H]

Identifier: 220932418

GI number: 220932418

Start: 1694168

End: 1695352

Strand: Reverse

Name: pgk [H]

Synonym: Hore_15820

Alternate gene names: 220932418

Gene position: 1695352-1694168 (Counterclockwise)

Preceding gene: 220932419

Following gene: 220932417

Centisome position: 65.76

GC content: 44.81

Gene sequence:

>1185_bases
GTGAAAAAGACCCTGAAGGATGTTGATTTCAAGGGTAAAAGAACGCTGGTAAGAGTAGATTTCAATGTACCTCTTGAAGA
TGGTAAGATTACCGATGATACCAGAATTGAGGCCGCATTACCTACTATAAAATACCTGGTTGATGAAGGGGCAAAGGTTA
TATTAATGTCGCATCTGGGTCGTCCCAAAGGTAAGGTCGTAGATTCTTTAAGACTTGATCCTGTAGCCCAGAGGCTGGCC
GAGTTACTCGGAAAAGAAGTTACCAAGGTTGATGACTGTATTGGAGATGAACCTAAAGAAGCAGTAAGTGAAATGGAAAA
TGGGGATGTTCTCCTTTTAGAAAATACCCGTTTTCACGCCGGTGAAAAGAAAAATGACCCCGATTTCGCCAGACAGCTGG
CTGAACTGGCCGAGGTATTTGTAAATGATGCCTTTGGTGCTGCCCACCGGGCCCATGCTTCTACTGTAGGGGTCACCGAG
CATTTACCATCTGTAGCCGGATTTTTATTGCAGAGGGAGTTAAATGCCCTGGGAGAGGCTATGGAGAACCCCGGACATCC
CTTTGTTGCTATCTTAGGTGGTGCCAAGGTTTCAGATAAAATCGGGGTTATTAAAAATCTCCTCGATAAAGTAGACTACC
TCCTGGTTGGTGGTGGTATTGCCAATACCTTCTTACTGGCCAAGGGTTATGAAGTAGGGGATTCCCTGGTTGAAGAGGAC
AAAGTAGAGCTGGCTAAAGAGCTCTTAAAAGAAGCTGAGGAAAAAGGTGTTGACCTTGTTTTACCTGAAGATGTAGTTAT
TGCTGAAGAATTTAAAGAAGATGCCAACCATAAAGTTGTCAGTGCTGATAGTATTCCTGAAGGCTGGCAAATCCTTGACA
GTGGTGGGCCAAAAACCATCGAGAAATACAGTGATATCATCGCTAAAGCTGAAACCGTTATCTGGAATGGACCTATCGGG
GTTTTTGAAATGGATACCTTTGCTAAAGGTACCAATGCCCTGGCTGAAGCTATGGCCAGATCCAGTGCCAGAACCGTAAT
TGGTGGTGGTGACTCCGCAGCTGCTGTTAAGAAAGCCGGTTTAGAGGATAAGATGAGTCATATTTCAACCGGTGGTGGTG
CTTCCCTGATGTTCTTTGAAGGAAAGCCCTTACCCGGTGTTGAAGCATTAGATGATGTTGAGTAA

Upstream 100 bases:

>100_bases
AATGAGACTGTATATATTAGGGATGGTTCGTATATTACTTTTCTCAGTTTAGCCCGGTATATTTCGGGATAAACGACAAA
TAATAATGGAGGTGGGATAA

Downstream 100 bases:

>100_bases
GGAGGGGATTTTGTGAGGACACCGTTTATTGCCGGTAACTGGAAGATGAACTTGACATTGAAAGAATCGGTGGCCCTGGT
AGAAGAATTAAAAGACCTGG

Product: Phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKKTLKDVDFKGKRTLVRVDFNVPLEDGKITDDTRIEAALPTIKYLVDEGAKVILMSHLGRPKGKVVDSLRLDPVAQRLA
ELLGKEVTKVDDCIGDEPKEAVSEMENGDVLLLENTRFHAGEKKNDPDFARQLAELAEVFVNDAFGAAHRAHASTVGVTE
HLPSVAGFLLQRELNALGEAMENPGHPFVAILGGAKVSDKIGVIKNLLDKVDYLLVGGGIANTFLLAKGYEVGDSLVEED
KVELAKELLKEAEEKGVDLVLPEDVVIAEEFKEDANHKVVSADSIPEGWQILDSGGPKTIEKYSDIIAKAETVIWNGPIG
VFEMDTFAKGTNALAEAMARSSARTVIGGGDSAAAVKKAGLEDKMSHISTGGGASLMFFEGKPLPGVEALDDVE

Sequences:

>Translated_394_residues
MKKTLKDVDFKGKRTLVRVDFNVPLEDGKITDDTRIEAALPTIKYLVDEGAKVILMSHLGRPKGKVVDSLRLDPVAQRLA
ELLGKEVTKVDDCIGDEPKEAVSEMENGDVLLLENTRFHAGEKKNDPDFARQLAELAEVFVNDAFGAAHRAHASTVGVTE
HLPSVAGFLLQRELNALGEAMENPGHPFVAILGGAKVSDKIGVIKNLLDKVDYLLVGGGIANTFLLAKGYEVGDSLVEED
KVELAKELLKEAEEKGVDLVLPEDVVIAEEFKEDANHKVVSADSIPEGWQILDSGGPKTIEKYSDIIAKAETVIWNGPIG
VFEMDTFAKGTNALAEAMARSSARTVIGGGDSAAAVKKAGLEDKMSHISTGGGASLMFFEGKPLPGVEALDDVE
>Mature_394_residues
MKKTLKDVDFKGKRTLVRVDFNVPLEDGKITDDTRIEAALPTIKYLVDEGAKVILMSHLGRPKGKVVDSLRLDPVAQRLA
ELLGKEVTKVDDCIGDEPKEAVSEMENGDVLLLENTRFHAGEKKNDPDFARQLAELAEVFVNDAFGAAHRAHASTVGVTE
HLPSVAGFLLQRELNALGEAMENPGHPFVAILGGAKVSDKIGVIKNLLDKVDYLLVGGGIANTFLLAKGYEVGDSLVEED
KVELAKELLKEAEEKGVDLVLPEDVVIAEEFKEDANHKVVSADSIPEGWQILDSGGPKTIEKYSDIIAKAETVIWNGPIG
VFEMDTFAKGTNALAEAMARSSARTVIGGGDSAAAVKKAGLEDKMSHISTGGGASLMFFEGKPLPGVEALDDVE

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=415, Percent_Identity=47.710843373494, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI31543397, Length=415, Percent_Identity=47.710843373494, Blast_Score=368, Evalue=1e-102,
Organism=Escherichia coli, GI1789294, Length=390, Percent_Identity=45.1282051282051, Blast_Score=314, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI17508823, Length=414, Percent_Identity=49.0338164251208, Blast_Score=381, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319857, Length=412, Percent_Identity=49.2718446601942, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24581203, Length=413, Percent_Identity=45.0363196125908, Blast_Score=334, Evalue=5e-92,
Organism=Drosophila melanogaster, GI17136394, Length=410, Percent_Identity=44.6341463414634, Blast_Score=320, Evalue=1e-87,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42251; Mature: 42251

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLKDVDFKGKRTLVRVDFNVPLEDGKITDDTRIEAALPTIKYLVDEGAKVILMSHLG
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHCC
RPKGKVVDSLRLDPVAQRLAELLGKEVTKVDDCIGDEPKEAVSEMENGDVLLLENTRFHA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCEECC
GEKKNDPDFARQLAELAEVFVNDAFGAAHRAHASTVGVTEHLPSVAGFLLQRELNALGEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MENPGHPFVAILGGAKVSDKIGVIKNLLDKVDYLLVGGGIANTFLLAKGYEVGDSLVEED
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHCCCCHHHHHHHHHH
KVELAKELLKEAEEKGVDLVLPEDVVIAEEFKEDANHKVVSADSIPEGWQILDSGGPKTI
HHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCCCCHHH
EKYSDIIAKAETVIWNGPIGVFEMDTFAKGTNALAEAMARSSARTVIGGGDSAAAVKKAG
HHHHHHHHHHHEEEECCCCCEEECHHHHCCHHHHHHHHHHCCCCEEECCCCCHHHHHHCC
LEDKMSHISTGGGASLMFFEGKPLPGVEALDDVE
HHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCCC
>Mature Secondary Structure
MKKTLKDVDFKGKRTLVRVDFNVPLEDGKITDDTRIEAALPTIKYLVDEGAKVILMSHLG
CCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHCC
RPKGKVVDSLRLDPVAQRLAELLGKEVTKVDDCIGDEPKEAVSEMENGDVLLLENTRFHA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCEECC
GEKKNDPDFARQLAELAEVFVNDAFGAAHRAHASTVGVTEHLPSVAGFLLQRELNALGEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MENPGHPFVAILGGAKVSDKIGVIKNLLDKVDYLLVGGGIANTFLLAKGYEVGDSLVEED
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHCCCCHHHHHHHHHH
KVELAKELLKEAEEKGVDLVLPEDVVIAEEFKEDANHKVVSADSIPEGWQILDSGGPKTI
HHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCCCCHHH
EKYSDIIAKAETVIWNGPIGVFEMDTFAKGTNALAEAMARSSARTVIGGGDSAAAVKKAG
HHHHHHHHHHHEEEECCCCCEEECHHHHCCHHHHHHHHHHCCCCEEECCCCCHHHHHHCC
LEDKMSHISTGGGASLMFFEGKPLPGVEALDDVE
HHHHHHHHCCCCCCEEEEECCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA