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The map label for this gene is apbE [H]

Identifier: 220932320

GI number: 220932320

Start: 1579596

End: 1580678

Strand: Reverse

Name: apbE [H]

Synonym: Hore_14840

Alternate gene names: 220932320

Gene position: 1580678-1579596 (Counterclockwise)

Preceding gene: 220932321

Following gene: 220932319

Centisome position: 61.31

GC content: 41.18

Gene sequence:

>1083_bases
ATGAAATTATATATGCAAAAAAGGTGTTGCGGGATTATCGCAGTCATATGTTTAGTCTTAATAGTTGTCTTCGTGTTAAA
TGGCTGTCAGGGACAAAAAGAAAAGAATGATTTGCCTGCTGCCAGCAAATCTTCTTTTTTAATGGATACCATTGTAAGTA
TGAAGGTTTATGGTGAAAAGCCAGACAAAGTTATTGAAGAGGCTTTTCAGAGAATGCGTGAAATCGAGAATGAGATGAGT
GTTACCCTTAAATCCAGCTATATTTACAAAATTAATTCTAACCCGGGAGAACCGGTCAAGGTTGATTCTGATACCTTTCG
TGTTATTAGAAAGGCAATAACTTATGCTGAAATAACCGATGGTAATTTTGATCCCAGTATCAGGCCTCTGGTCAGCCTCT
GGGGTATAGGTACTGAAAATGCACGGGTACCTGCCCGGTCAGAGATCGAAGAGGCAAAAAGGTTGGTTAATTATAAGTTG
ATTAAGCTTGATGAAGAAGAAAAGACGGTAGTGTTGCAAAAACCGGGTATGGGAATAGACCTGGGTGCTATTGCTAAAGG
ATATGCGGCAGATGAAGTCAGGAGGATATTTAAAAAACACCGTGTTGAGCATGCCTTTGTAAATCTGGGGGGAAATGTTC
TGGTTGTAGGTGGCAAGCCCGATGGTTCGCCCTGGGTTGTGGGGATTCAGGACCCCCGTCGGGAACGGGGTAGTGTTATG
GCCAGTTTTAAGGTTAAGGATAAGGCTATTGTAACTTCGGGTAATTATGAACGGTATTTTGAAAAAGACGGGGTGGTTTA
CCACCATATTATTGATCCCAAAACAGGCTCACCGGCCCGGACAAATCTTTTGAGTGCTACCATTATCTGTGATGATTCTT
TTGATGCCGATGCCCTATCAACCAGTGTCTTTGTCATGGGGGTTGATAGAGGACTGGAGCTAGTGGAGAGCCTTAATGGG
GTTGAAGTTATGTTTATAAATAAAGATTTAGAGATAATTCTGTCAGAAGGCCTTAAGAATAAGATTAAGGTCCTGAACCA
GGATTTTAAACTTGTAGGGAATGATAATGATGAGCAAATATAG

Upstream 100 bases:

>100_bases
GGCTTTCATTTATCTTTTAAATGATTTTGTCAAAGGCTAATTTATTCTTAATTTTAACGGAATAATAGAACAATAGAGAA
ATAACAGGGTGTGAAGGCTT

Downstream 100 bases:

>100_bases
TATTGCCGAGTACAGACAGAGATTTGCTCCGGTTATTGAAAAAATAGATGAAATTATATGGGAGATAACTAAAACCAGGG
TGGGGTTAATTAATATAGCT

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKLYMQKRCCGIIAVICLVLIVVFVLNGCQGQKEKNDLPAASKSSFLMDTIVSMKVYGEKPDKVIEEAFQRMREIENEMS
VTLKSSYIYKINSNPGEPVKVDSDTFRVIRKAITYAEITDGNFDPSIRPLVSLWGIGTENARVPARSEIEEAKRLVNYKL
IKLDEEEKTVVLQKPGMGIDLGAIAKGYAADEVRRIFKKHRVEHAFVNLGGNVLVVGGKPDGSPWVVGIQDPRRERGSVM
ASFKVKDKAIVTSGNYERYFEKDGVVYHHIIDPKTGSPARTNLLSATIICDDSFDADALSTSVFVMGVDRGLELVESLNG
VEVMFINKDLEIILSEGLKNKIKVLNQDFKLVGNDNDEQI

Sequences:

>Translated_360_residues
MKLYMQKRCCGIIAVICLVLIVVFVLNGCQGQKEKNDLPAASKSSFLMDTIVSMKVYGEKPDKVIEEAFQRMREIENEMS
VTLKSSYIYKINSNPGEPVKVDSDTFRVIRKAITYAEITDGNFDPSIRPLVSLWGIGTENARVPARSEIEEAKRLVNYKL
IKLDEEEKTVVLQKPGMGIDLGAIAKGYAADEVRRIFKKHRVEHAFVNLGGNVLVVGGKPDGSPWVVGIQDPRRERGSVM
ASFKVKDKAIVTSGNYERYFEKDGVVYHHIIDPKTGSPARTNLLSATIICDDSFDADALSTSVFVMGVDRGLELVESLNG
VEVMFINKDLEIILSEGLKNKIKVLNQDFKLVGNDNDEQI
>Mature_360_residues
MKLYMQKRCCGIIAVICLVLIVVFVLNGCQGQKEKNDLPAASKSSFLMDTIVSMKVYGEKPDKVIEEAFQRMREIENEMS
VTLKSSYIYKINSNPGEPVKVDSDTFRVIRKAITYAEITDGNFDPSIRPLVSLWGIGTENARVPARSEIEEAKRLVNYKL
IKLDEEEKTVVLQKPGMGIDLGAIAKGYAADEVRRIFKKHRVEHAFVNLGGNVLVVGGKPDGSPWVVGIQDPRRERGSVM
ASFKVKDKAIVTSGNYERYFEKDGVVYHHIIDPKTGSPARTNLLSATIICDDSFDADALSTSVFVMGVDRGLELVESLNG
VEVMFINKDLEIILSEGLKNKIKVLNQDFKLVGNDNDEQI

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=271, Percent_Identity=30.2583025830258, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 40082; Mature: 40082

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYMQKRCCGIIAVICLVLIVVFVLNGCQGQKEKNDLPAASKSSFLMDTIVSMKVYGEK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PDKVIEEAFQRMREIENEMSVTLKSSYIYKINSNPGEPVKVDSDTFRVIRKAITYAEITD
HHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCEEECCHHHHHHHHHHHHEEECC
GNFDPSIRPLVSLWGIGTENARVPARSEIEEAKRLVNYKLIKLDEEEKTVVLQKPGMGID
CCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCCEEEEECCCCCCC
LGAIAKGYAADEVRRIFKKHRVEHAFVNLGGNVLVVGGKPDGSPWVVGIQDPRRERGSVM
HHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEECCCCCCCCCCEE
ASFKVKDKAIVTSGNYERYFEKDGVVYHHIIDPKTGSPARTNLLSATIICDDSFDADALS
EEEEECCEEEEECCCCHHHHCCCCEEEEEEECCCCCCCCHHHEEEEEEEECCCCCCCHHC
TSVFVMGVDRGLELVESLNGVEVMFINKDLEIILSEGLKNKIKVLNQDFKLVGNDNDEQI
CEEEEEECCHHHHHHHCCCCEEEEEECCCHHHHHHHCHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure
MKLYMQKRCCGIIAVICLVLIVVFVLNGCQGQKEKNDLPAASKSSFLMDTIVSMKVYGEK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PDKVIEEAFQRMREIENEMSVTLKSSYIYKINSNPGEPVKVDSDTFRVIRKAITYAEITD
HHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCEEECCHHHHHHHHHHHHEEECC
GNFDPSIRPLVSLWGIGTENARVPARSEIEEAKRLVNYKLIKLDEEEKTVVLQKPGMGID
CCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCCEEEEECCCCCCC
LGAIAKGYAADEVRRIFKKHRVEHAFVNLGGNVLVVGGKPDGSPWVVGIQDPRRERGSVM
HHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEECCCCCCCCCCEE
ASFKVKDKAIVTSGNYERYFEKDGVVYHHIIDPKTGSPARTNLLSATIICDDSFDADALS
EEEEECCEEEEECCCCHHHHCCCCEEEEEEECCCCCCCCHHHEEEEEEEECCCCCCCHHC
TSVFVMGVDRGLELVESLNGVEVMFINKDLEIILSEGLKNKIKVLNQDFKLVGNDNDEQI
CEEEEEECCHHHHHHHCCCCEEEEEECCCHHHHHHHCHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]