Click here to switch to the map view.

The map label for this gene is cat [H]

Identifier: 220932222

GI number: 220932222

Start: 1475945

End: 1476730

Strand: Reverse

Name: cat [H]

Synonym: Hore_13840

Alternate gene names: 220932222

Gene position: 1476730-1475945 (Counterclockwise)

Preceding gene: 220932223

Following gene: 220932219

Centisome position: 57.28

GC content: 28.63

Gene sequence:

>786_bases
ATGCCCTCTGTCACAAAGCTTGAAACAAATGAGGGTAGTAATACAGCCGCGTCGTCAAGCTTTGTGCCAGGCTTGGCACG
GGCACGTCGGAAATGCCTGGGACGTTATACGAAAGCCAGGCTAATATACTTAAAAATGGAGGTAAATATGAAGAAAATAG
ATCTTTCTAAATGGTCACGAAAAGAACATTATAATTTCTTTAAACAATTAGATATTCCCTATTTTAATATAACAACAGAT
ATTGATATAACAAAGTTTTATTCTTTTATTAAACAAAATGATTATTCATTTTTTAAAACTTTACTATATTTCGTTATGAA
AACTGCAAATGAAAATGATAACTTCAAATTACGTATAAGTAATGAGGAAATTATTAAGCACAATAAAATCAGTCCATCTT
TTACATACTTAATGGATGAAGAAACCTTTAATTTTTGTTATGCAGAATATGACAATAACTTTGATAATTTTATAAAAAAT
GTTGAAAAATCTATTAAAAACAGCACTGGAAACCTTATTGATAGTGATAAAGAAGCTAGAGATGATTTGATTTATATAAC
TAGTATTCCCTGGGTTTCATTCAAAAGTATTTCACATCCAATTAATTTAAATCCTATTGATTCAGTACCTAGAATCGCAT
GGGGAAAATATTTTAAAGAAAATGAATTATTAAAGTTACCCTTTTCAGTTCAGGTCCATCATGCATTAATGGATGGGCTT
CATGTTGGTAAATATATTAATAAATTACAAGATAAATTATATAATCCAGAAAAGGTAGTATTATAA

Upstream 100 bases:

>100_bases
GTGAATAATAAGGGATAAATTATGCAAAAACGTCACATAACAAGGCATTTCCGCTTACTGAGAGAGGAAATAAAGTATTA
TCGTCCGTTGCCTAAAGGAC

Downstream 100 bases:

>100_bases
GTAATTTTAACCAAAAATTTAACAAAATAAAAAGACCGCCTTGCCATCGTATAACACGGTATTTCCGCTACGGCCTAGCG
GCCTGCCTTCGGACATGCCC

Product: Chloramphenicol O-acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPSVTKLETNEGSNTAASSSFVPGLARARRKCLGRYTKARLIYLKMEVNMKKIDLSKWSRKEHYNFFKQLDIPYFNITTD
IDITKFYSFIKQNDYSFFKTLLYFVMKTANENDNFKLRISNEEIIKHNKISPSFTYLMDEETFNFCYAEYDNNFDNFIKN
VEKSIKNSTGNLIDSDKEARDDLIYITSIPWVSFKSISHPINLNPIDSVPRIAWGKYFKENELLKLPFSVQVHHALMDGL
HVGKYINKLQDKLYNPEKVVL

Sequences:

>Translated_261_residues
MPSVTKLETNEGSNTAASSSFVPGLARARRKCLGRYTKARLIYLKMEVNMKKIDLSKWSRKEHYNFFKQLDIPYFNITTD
IDITKFYSFIKQNDYSFFKTLLYFVMKTANENDNFKLRISNEEIIKHNKISPSFTYLMDEETFNFCYAEYDNNFDNFIKN
VEKSIKNSTGNLIDSDKEARDDLIYITSIPWVSFKSISHPINLNPIDSVPRIAWGKYFKENELLKLPFSVQVHHALMDGL
HVGKYINKLQDKLYNPEKVVL
>Mature_260_residues
PSVTKLETNEGSNTAASSSFVPGLARARRKCLGRYTKARLIYLKMEVNMKKIDLSKWSRKEHYNFFKQLDIPYFNITTDI
DITKFYSFIKQNDYSFFKTLLYFVMKTANENDNFKLRISNEEIIKHNKISPSFTYLMDEETFNFCYAEYDNNFDNFIKNV
EKSIKNSTGNLIDSDKEARDDLIYITSIPWVSFKSISHPINLNPIDSVPRIAWGKYFKENELLKLPFSVQVHHALMDGLH
VGKYINKLQDKLYNPEKVVL

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 30629; Mature: 30498

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVTKLETNEGSNTAASSSFVPGLARARRKCLGRYTKARLIYLKMEVNMKKIDLSKWSR
CCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEECCEEEECHHHHHH
KEHYNFFKQLDIPYFNITTDIDITKFYSFIKQNDYSFFKTLLYFVMKTANENDNFKLRIS
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
NEEIIKHNKISPSFTYLMDEETFNFCYAEYDNNFDNFIKNVEKSIKNSTGNLIDSDKEAR
CHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
DDLIYITSIPWVSFKSISHPINLNPIDSVPRIAWGKYFKENELLKLPFSVQVHHALMDGL
CCEEEEEECCCEEHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
HVGKYINKLQDKLYNPEKVVL
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PSVTKLETNEGSNTAASSSFVPGLARARRKCLGRYTKARLIYLKMEVNMKKIDLSKWSR
CCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEECCEEEECHHHHHH
KEHYNFFKQLDIPYFNITTDIDITKFYSFIKQNDYSFFKTLLYFVMKTANENDNFKLRIS
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
NEEIIKHNKISPSFTYLMDEETFNFCYAEYDNNFDNFIKNVEKSIKNSTGNLIDSDKEAR
CHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
DDLIYITSIPWVSFKSISHPINLNPIDSVPRIAWGKYFKENELLKLPFSVQVHHALMDGL
CCEEEEEECCCEEHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
HVGKYINKLQDKLYNPEKVVL
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3900035 [H]