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The map label for this gene is sthA [C]

Identifier: 220932154

GI number: 220932154

Start: 1415473

End: 1416744

Strand: Reverse

Name: sthA [C]

Synonym: Hore_13170

Alternate gene names: 220932154

Gene position: 1416744-1415473 (Counterclockwise)

Preceding gene: 220932155

Following gene: 220932152

Centisome position: 54.95

GC content: 41.82

Gene sequence:

>1272_bases
ATGACTGAATATGATGTTATTGTATGTGGTGGTGGTCCCGGGGGGATCGCAGCTTCCATTGGGGCTGCCCGGATGGGCAA
AAAAGTCCTTCTGGTAGAAAGGTATGGTTTTCTCGGTGGTGGGGCAACAGCCATGCTGGTAAACCCCTTTATGACCTACT
ATTCAGGAGAAAGACAGATTATCAGGGGTATTTTCCAGGAAATAGTAGAACGGTTAAAGGATATGAACGCCTTTGGTAAC
AGCTTAATGAAAGAAACCCCCTGGGCCTTTGACCCTGAAGCTTTTAAGGTGGTAGCTGACCGTCTCTGCTCGGAAAATGG
AGTTAATATCCATTTCCATGCCATGTTAGCCGGTGTTGAAACCTGTGGAAATGAAATTAACAGTATAAAGGTGGTTACTA
AAGGTGGTTTAAAGAAATTAAAGGCTAAAATATATGTTGATAGTACTGGTGATGCTGATCTGGCTTATTTAGCAGGGGTT
AGAGTAGAAAAAGGGAGACCTAAGGATGGTTTAACCCAGCCCATGACCTTGAATTTTAGAATGGCCAACGTAGACTTAGA
AAGAATGCCTTCCCGGGGAGAAATAACAGAAAAATATATAGAAGCTAAAGAGAAAGGAATAATTGACTGTCCCCGTGAAG
ATATTTTATTTTTCTTTACAACAAACCCCGGGGTGGTCCATTTTAACCAGACCAGGGTTATTAAGCATGACCCTACTGAT
TCTGAGTCTTTGAGCAAAGCAGAAATTGAAGGAAGAAGGCAGAGCTGGGAGTTATCACGGTGGTTAATTAAAAATATTCC
TGGGTTTGAGAATGCCTATCTTCAGCAAACAGCAACCCAGATAGGGATCAGGGAATCACGCCGGGTTATTGGGGATTATG
TATTAACTGTTAATGACCTCCTGAAAACTAGAAAATTTGATGATGTTGTTGCCTGTGGGAGTTATCCTATAGATATTCAT
AATCCAGAGGGTGAAGGTACGATTATGAAGTACCTTGAAGAAGGAGAATGGTATGACATCCCTTATCGTTGCCTTGTTCC
TCAAAACTTAAATAATTTACTGATCGGTAGCCGTTCTATTTCGTCAACCCATGAGGCCCATTCTTCATTGAGGGTTATGC
CTATAGTTTTTGCCATTGGTCAGGCAGCTGGAATTGCAGCTGCAGTCAGTCTGGAAACAGGTAAAAACCCGCATCGAATC
GATTATAGAATTTTACAGGAAGAGTTAATAAAACAGGGGGCTTTTCTGGGTGATAATGTAATAGTGGAGTAA

Upstream 100 bases:

>100_bases
GTTAAAGGATAAAATATATTTGTATTATATATAAACTTATAAAGATATATTTATAAAATAAATGCTAAAATGTTTAAGGA
CTTAATGGAGGTAGTTTGTT

Downstream 100 bases:

>100_bases
TTATAAAATAAAATTTTTATAATATAATTTAAAAGAATTAATTAATAGGTGTATTATATATATGACTAAATATAAATAAA
AGATAATATAAATAAAAAAC

Product: FAD dependent oxidoreductase

Products: H+; Nicotinamide adenine dinucleotide; Nicotinamide adenine dinucleotide phosphate - reduced [C]

Alternate protein names: Invasion Protein IbeA; Glucose-Inhibited Division Protein A; Pyridine Nucleotide-Disulphide Oxidoreductase; Fumarate Reductase/Succinate Dehydrogenase Flavoprotein; Coagulation Factor 5/8 Type Domain Protein; Dihydrolipoamide Dehydrogenase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Thiamine Biosynthesis Thi4 Protein; Invasion Protein IbeA Family Protein; Protein Involved In Invasion; FAD Dependent Oxidoreductase Domain Protein; Invasion Protein; Pyridine Nucleotide-Disulfide Oxidoreductase Family; tRNA Uridine 5-Carboxymethylaminomethyl GidA; Pyridine Nucleotide-Disulfide Oxidoreductase

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTEYDVIVCGGGPGGIAASIGAARMGKKVLLVERYGFLGGGATAMLVNPFMTYYSGERQIIRGIFQEIVERLKDMNAFGN
SLMKETPWAFDPEAFKVVADRLCSENGVNIHFHAMLAGVETCGNEINSIKVVTKGGLKKLKAKIYVDSTGDADLAYLAGV
RVEKGRPKDGLTQPMTLNFRMANVDLERMPSRGEITEKYIEAKEKGIIDCPREDILFFFTTNPGVVHFNQTRVIKHDPTD
SESLSKAEIEGRRQSWELSRWLIKNIPGFENAYLQQTATQIGIRESRRVIGDYVLTVNDLLKTRKFDDVVACGSYPIDIH
NPEGEGTIMKYLEEGEWYDIPYRCLVPQNLNNLLIGSRSISSTHEAHSSLRVMPIVFAIGQAAGIAAAVSLETGKNPHRI
DYRILQEELIKQGAFLGDNVIVE

Sequences:

>Translated_423_residues
MTEYDVIVCGGGPGGIAASIGAARMGKKVLLVERYGFLGGGATAMLVNPFMTYYSGERQIIRGIFQEIVERLKDMNAFGN
SLMKETPWAFDPEAFKVVADRLCSENGVNIHFHAMLAGVETCGNEINSIKVVTKGGLKKLKAKIYVDSTGDADLAYLAGV
RVEKGRPKDGLTQPMTLNFRMANVDLERMPSRGEITEKYIEAKEKGIIDCPREDILFFFTTNPGVVHFNQTRVIKHDPTD
SESLSKAEIEGRRQSWELSRWLIKNIPGFENAYLQQTATQIGIRESRRVIGDYVLTVNDLLKTRKFDDVVACGSYPIDIH
NPEGEGTIMKYLEEGEWYDIPYRCLVPQNLNNLLIGSRSISSTHEAHSSLRVMPIVFAIGQAAGIAAAVSLETGKNPHRI
DYRILQEELIKQGAFLGDNVIVE
>Mature_422_residues
TEYDVIVCGGGPGGIAASIGAARMGKKVLLVERYGFLGGGATAMLVNPFMTYYSGERQIIRGIFQEIVERLKDMNAFGNS
LMKETPWAFDPEAFKVVADRLCSENGVNIHFHAMLAGVETCGNEINSIKVVTKGGLKKLKAKIYVDSTGDADLAYLAGVR
VEKGRPKDGLTQPMTLNFRMANVDLERMPSRGEITEKYIEAKEKGIIDCPREDILFFFTTNPGVVHFNQTRVIKHDPTDS
ESLSKAEIEGRRQSWELSRWLIKNIPGFENAYLQQTATQIGIRESRRVIGDYVLTVNDLLKTRKFDDVVACGSYPIDIHN
PEGEGTIMKYLEEGEWYDIPYRCLVPQNLNNLLIGSRSISSTHEAHSSLRVMPIVFAIGQAAGIAAAVSLETGKNPHRID
YRILQEELIKQGAFLGDNVIVE

Specific function: Conversion Of NADPH, Generated By Peripheral Catabolic Pathways, To NADH, Which Can Enter The Respiratory Chain For Energy Generation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.1.1 [C]

Molecular weight: Translated: 46971; Mature: 46839

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYDVIVCGGGPGGIAASIGAARMGKKVLLVERYGFLGGGATAMLVNPFMTYYSGERQI
CCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHH
IRGIFQEIVERLKDMNAFGNSLMKETPWAFDPEAFKVVADRLCSENGVNIHFHAMLAGVE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
TCGNEINSIKVVTKGGLKKLKAKIYVDSTGDADLAYLAGVRVEKGRPKDGLTQPMTLNFR
HHCCCCCEEEEEECCCCEEEEEEEEEECCCCCCEEEHCCEEEECCCCCCCCCCCEEEEEE
MANVDLERMPSRGEITEKYIEAKEKGIIDCPREDILFFFTTNPGVVHFNQTRVIKHDPTD
EECCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCEEEEEECCCC
SESLSKAEIEGRRQSWELSRWLIKNIPGFENAYLQQTATQIGIRESRRVIGDYVLTVNDL
CCHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
LKTRKFDDVVACGSYPIDIHNPEGEGTIMKYLEEGEWYDIPYRCLVPQNLNNLLIGSRSI
HHHCCCCCEEECCCCEEEEECCCCCCHHHHHHHCCCEECCCEEEECCCCCCCEEEECCCC
SSTHEAHSSLRVMPIVFAIGQAAGIAAAVSLETGKNPHRIDYRILQEELIKQGAFLGDNV
CHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
IVE
EEC
>Mature Secondary Structure 
TEYDVIVCGGGPGGIAASIGAARMGKKVLLVERYGFLGGGATAMLVNPFMTYYSGERQI
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHH
IRGIFQEIVERLKDMNAFGNSLMKETPWAFDPEAFKVVADRLCSENGVNIHFHAMLAGVE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
TCGNEINSIKVVTKGGLKKLKAKIYVDSTGDADLAYLAGVRVEKGRPKDGLTQPMTLNFR
HHCCCCCEEEEEECCCCEEEEEEEEEECCCCCCEEEHCCEEEECCCCCCCCCCCEEEEEE
MANVDLERMPSRGEITEKYIEAKEKGIIDCPREDILFFFTTNPGVVHFNQTRVIKHDPTD
EECCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCEEEEEECCCC
SESLSKAEIEGRRQSWELSRWLIKNIPGFENAYLQQTATQIGIRESRRVIGDYVLTVNDL
CCHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
LKTRKFDDVVACGSYPIDIHNPEGEGTIMKYLEEGEWYDIPYRCLVPQNLNNLLIGSRSI
HHHCCCCCEEECCCCEEEEECCCCCCHHHHHHHCCCEECCCEEEECCCCCCCEEEECCCC
SSTHEAHSSLRVMPIVFAIGQAAGIAAAVSLETGKNPHRIDYRILQEELIKQGAFLGDNV
CHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
IVE
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 2'-AMP; FAD; p-Hydroxymercuribenzoate [C]

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H+; Nicotinamide adenine dinucleotide - reduced; Nicotinamide adenine dinucleotide phosphate [C]

Specific reaction: (2) H+ (Extracellular) + Nicotinamide adenine dinucleotide - reduced + Nicotinamide adenine dinucleotide phosphate --> (2) H+ + Nicotinamide adenine dinucleotide + Nicotinamide adenine dinucleotide phosphate - reduced [C]

General reaction: Redox reaction [C]

Inhibitor: p-Hydroxy mercuribenzoate reducedsubstrate, [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA