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The map label for this gene is exuR [H]

Identifier: 220932152

GI number: 220932152

Start: 1413141

End: 1414175

Strand: Reverse

Name: exuR [H]

Synonym: Hore_13150

Alternate gene names: 220932152

Gene position: 1414175-1413141 (Counterclockwise)

Preceding gene: 220932154

Following gene: 220932151

Centisome position: 54.85

GC content: 30.82

Gene sequence:

>1035_bases
ATGGCTCCAACAATTAAAGATGTAGCAGAAAAAGCAGGGGTTTCACCGGCTACTGTGTCGAGGGTTTTTAATAACAAAGG
GAGTATTGCTGACCATACTCGTAAGAAAGTTCTGGAAGCAGCTAAAAAACTAAAATATACTCCGCGAAACTATACAAAAA
ACAATAGAAAAAAAGGAGAAAATGTAGGTATAATTTTCAGTAAACGTATCTCCACAAATCTAGTTGGAGATCCTTTTTAT
GGGCAGGTTATGGAAGGTGTTGAAGAAAGTTTAAAAAAATATAATTATAATTTGTTTTTTAAAACAATTTCCGGCATAAA
GAACGAAGATGTTTATACAATTAATTCTTTAATCAAAGATCAGGATCTAGCTGGTTTAATTTTAACGGGTTATGAAATAG
ATAAAGAATTAATTTTAGACATAAAAAATAGTAATATACCTCTTGTGTTAATTGATAATGATTTATGGGATGAGAATATA
GATTGTGTGGTTACCGATAACATATCTGGAGCCAGAAAAATAGTAAATTATTTAATTGAATTGGGTCATAAACGTATAGC
TTTTTTTGGAGGCCCTTTAAGTCATGTTTCCCTTGAAGAGAGGTATATTGGTTATAAGCAGGCTTTAAAACTGGCTGGTA
TTGAAAAAGATGATAACTTAATATATTTCTGTAAACCTTTTAGTGAAATAGCGGATGCTTTCAAAGCTGCTTACAGTTTT
TTTTCGAATGTGAAGACTTTACCTTCTGCAGTTTTTACTGGAAATGATAAAATTGCTATCGGTGTAATGAAAGCATTAAA
AGAGTTAGGTTATAGAATCCCTCAAGATATATCTATTGCAGGTTTTGATGATATTGAAATGGCCAAACACACTCTTCCAT
CTCTTACTACAGTTAGAATATTTAAAAAAGAAATGGGTATTTTAGCTGGAAAACGATTGTATGAATTAATAAATAATATT
ACCCCAAGTCCTATCAAATTGGTTGTTTCTGTAGAAACCATTATTAGAGGTTCTACATCAAAATACTATAATTAA

Upstream 100 bases:

>100_bases
AGGATTTTATGAATTTTTGTAGTATAAATAATATTAGATAATAATTATTGTAATAAAAATAAAATAACTTTTTAAATATT
AATTTTAAGGAGTGAGAAAT

Downstream 100 bases:

>100_bases
TAGGTCATCTTAAAAAGAAAACAATTAATCAAGGGGGTGAAATTAATTAAATTAATTAGAGAAATAACATAAATAAGCCA
TGGAAAACAAACATAATAAA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAPTIKDVAEKAGVSPATVSRVFNNKGSIADHTRKKVLEAAKKLKYTPRNYTKNNRKKGENVGIIFSKRISTNLVGDPFY
GQVMEGVEESLKKYNYNLFFKTISGIKNEDVYTINSLIKDQDLAGLILTGYEIDKELILDIKNSNIPLVLIDNDLWDENI
DCVVTDNISGARKIVNYLIELGHKRIAFFGGPLSHVSLEERYIGYKQALKLAGIEKDDNLIYFCKPFSEIADAFKAAYSF
FSNVKTLPSAVFTGNDKIAIGVMKALKELGYRIPQDISIAGFDDIEMAKHTLPSLTTVRIFKKEMGILAGKRLYELINNI
TPSPIKLVVSVETIIRGSTSKYYN

Sequences:

>Translated_344_residues
MAPTIKDVAEKAGVSPATVSRVFNNKGSIADHTRKKVLEAAKKLKYTPRNYTKNNRKKGENVGIIFSKRISTNLVGDPFY
GQVMEGVEESLKKYNYNLFFKTISGIKNEDVYTINSLIKDQDLAGLILTGYEIDKELILDIKNSNIPLVLIDNDLWDENI
DCVVTDNISGARKIVNYLIELGHKRIAFFGGPLSHVSLEERYIGYKQALKLAGIEKDDNLIYFCKPFSEIADAFKAAYSF
FSNVKTLPSAVFTGNDKIAIGVMKALKELGYRIPQDISIAGFDDIEMAKHTLPSLTTVRIFKKEMGILAGKRLYELINNI
TPSPIKLVVSVETIIRGSTSKYYN
>Mature_343_residues
APTIKDVAEKAGVSPATVSRVFNNKGSIADHTRKKVLEAAKKLKYTPRNYTKNNRKKGENVGIIFSKRISTNLVGDPFYG
QVMEGVEESLKKYNYNLFFKTISGIKNEDVYTINSLIKDQDLAGLILTGYEIDKELILDIKNSNIPLVLIDNDLWDENID
CVVTDNISGARKIVNYLIELGHKRIAFFGGPLSHVSLEERYIGYKQALKLAGIEKDDNLIYFCKPFSEIADAFKAAYSFF
SNVKTLPSAVFTGNDKIAIGVMKALKELGYRIPQDISIAGFDDIEMAKHTLPSLTTVRIFKKEMGILAGKRLYELINNIT
PSPIKLVVSVETIIRGSTSKYYN

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=339, Percent_Identity=32.4483775811209, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790369, Length=339, Percent_Identity=30.0884955752212, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787580, Length=338, Percent_Identity=28.9940828402367, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787948, Length=347, Percent_Identity=28.8184438040346, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=32.1070234113712, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788474, Length=327, Percent_Identity=32.4159021406728, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786540, Length=327, Percent_Identity=28.7461773700306, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789068, Length=310, Percent_Identity=29.3548387096774, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789456, Length=342, Percent_Identity=27.4853801169591, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI48994940, Length=336, Percent_Identity=25.8928571428571, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787906, Length=336, Percent_Identity=26.7857142857143, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790715, Length=324, Percent_Identity=23.4567901234568, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=25.1552795031056, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786268, Length=288, Percent_Identity=22.2222222222222, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38483; Mature: 38352

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTIKDVAEKAGVSPATVSRVFNNKGSIADHTRKKVLEAAKKLKYTPRNYTKNNRKKGE
CCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NVGIIFSKRISTNLVGDPFYGQVMEGVEESLKKYNYNLFFKTISGIKNEDVYTINSLIKD
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHHHHCC
QDLAGLILTGYEIDKELILDIKNSNIPLVLIDNDLWDENIDCVVTDNISGARKIVNYLIE
CCCCEEEEECCCCCHHHEEEECCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHH
LGHKRIAFFGGPLSHVSLEERYIGYKQALKLAGIEKDDNLIYFCKPFSEIADAFKAAYSF
HCCCEEEEECCCHHHCCHHHHHHCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHH
FSNVKTLPSAVFTGNDKIAIGVMKALKELGYRIPQDISIAGFDDIEMAKHTLPSLTTVRI
HHHHHHHCHHEEECCCEEHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHCCCHHHHHH
FKKEMGILAGKRLYELINNITPSPIKLVVSVETIIRGSTSKYYN
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCCC
>Mature Secondary Structure 
APTIKDVAEKAGVSPATVSRVFNNKGSIADHTRKKVLEAAKKLKYTPRNYTKNNRKKGE
CCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NVGIIFSKRISTNLVGDPFYGQVMEGVEESLKKYNYNLFFKTISGIKNEDVYTINSLIKD
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHHHHCC
QDLAGLILTGYEIDKELILDIKNSNIPLVLIDNDLWDENIDCVVTDNISGARKIVNYLIE
CCCCEEEEECCCCCHHHEEEECCCCCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHH
LGHKRIAFFGGPLSHVSLEERYIGYKQALKLAGIEKDDNLIYFCKPFSEIADAFKAAYSF
HCCCEEEEECCCHHHCCHHHHHHCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHH
FSNVKTLPSAVFTGNDKIAIGVMKALKELGYRIPQDISIAGFDDIEMAKHTLPSLTTVRI
HHHHHHHCHHEEECCCEEHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHCCCHHHHHH
FKKEMGILAGKRLYELINNITPSPIKLVVSVETIIRGSTSKYYN
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]