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The map label for this gene is appC [H]

Identifier: 220932143

GI number: 220932143

Start: 1400787

End: 1402244

Strand: Reverse

Name: appC [H]

Synonym: Hore_13060

Alternate gene names: 220932143

Gene position: 1402244-1400787 (Counterclockwise)

Preceding gene: 220932144

Following gene: 220932142

Centisome position: 54.39

GC content: 41.02

Gene sequence:

>1458_bases
ATGAGCAATGGAAATATTCCAGTAAAACCTGGTAAAGGACCAGATGTCAAGTCTTCAGGCTGGAGTGATTTTAAGTCTTC
CCTGGGAGAATTCTGGCAGGAATTTAGCAGGGTAAAATATGGTAAATGGGGATTAGTTTTACTGGCTATTTTTATCCTTA
TGATTATTTTTAGCTCCCAGATTACACCTTTTAAAGAAGCGGGTACCAGATGGAGTGATATAGAATACTGGGAAGATAAT
CCCCAGAGTGCAGCCCCGGCCTGGATTAACTGGTTTTCATCACAGAAGAGAACTGAACATGAAATTTTAAGGGATCCGGA
GTGGAAGGTTATTGACAGAGGTAGAATGAAAACCTATAGTGGGTCATTTACCTATAATTACCAGTATGATATTCCACCTG
ATGAACTAATATTTAAGGCCCTGAGTAAAGGGACAGTAAATATGCAGGTCACCCTGGTCAGGCCCGATGGTGAGGAAATA
AGAATGACCCAGGCCAGTGTTAATTCCAGAAAAGAACAGAAGGTCAGGGCTCCTATGGCCAATGATGCCATGTTTGGAGC
ATACCGGCTTGCATCTAGGTTTGAGAGCCGTGAAAATTTAGAGAAAATAAATAAAAATTCTATCAACCCGATTAAAGTTA
TTTTTTCAAGAGGTCAGGAGGGAATTTTAATAAATCCCAGTCCCTTAAAGGGTGAATATAAGGTTAAGATTGAAGGAGTA
GCTATTGGTAAAGATTCATATATAAAGGAACCTTCTCTGATAGTTGCTGGAAAGGTGTATGGAATTCTGGGTACCGATAA
CGCCAAGCGGGATATCTGGAGTGGTATCGTAGTTGGAACTAAATGGGCAATGTTAATCGGGTTAATGACCTCATTTATAT
CGGTATCCGTAGGAGTTATTTATGGTGTTACCAGTGCTTATTTTGGTGGCTGGGTGGATTCGGCAATGATGAGGGTCTTT
GAGGTTTTTGTCAGTATACCGATGCTTCCGGTTCTAATTGTAGTCAGTGCTATTTTTAAACCCAGTATCTGGTTAATTAT
TTTAATGATGTGTATCTTCTACTGGACGGGACCGGTTAGAACAGTAAGGAGTATGGGTCTGCAAATAAAAGAAGAAACTT
ACATTGAAGCGGCAAAGGCCCTTAATGCTTCTAATTCCAGAATTATATTTAAACATATGATTCCCCAGCTAATTCCTTAT
GCTTTTGCTTCGATGGCCCTTTCAGTTCCAGGTGCTATTGTTGTTGAAGCCAGTTTGAGTTTGCTCGGGGTAGGCGATAC
GACAATAGTTACCTGGGGCCAGATACTCCACGGTGCCCATGTTAATGGGGCAGTTCTACAGGGCTTATGGTGGTGGGTAA
TACCACCAGGATTGGCAATTGCCCTGATGGGTATGACTTTTGCCTTTATTGGATTTTCTATGGATAAAATTCTAAATCCC
AAATTGAAGACGAGGTAG

Upstream 100 bases:

>100_bases
GTAATCTGTCGGTAACCATCCTGTTATACCTGGCTGGACTGGTAGTCCTTGACCTGATTTACGGTTTCCTCGATCCCCGT
ATAAAGGTAGGTGGTAAAGA

Downstream 100 bases:

>100_bases
ATATTATGGAGAAGATATTAGATGTCAGGAATTTAAAACTTCATTATTTTACAACCAAAGGTGCGGTTCATGGAGTTGAT
GGAGTATCCTTTTATATGAA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MSNGNIPVKPGKGPDVKSSGWSDFKSSLGEFWQEFSRVKYGKWGLVLLAIFILMIIFSSQITPFKEAGTRWSDIEYWEDN
PQSAAPAWINWFSSQKRTEHEILRDPEWKVIDRGRMKTYSGSFTYNYQYDIPPDELIFKALSKGTVNMQVTLVRPDGEEI
RMTQASVNSRKEQKVRAPMANDAMFGAYRLASRFESRENLEKINKNSINPIKVIFSRGQEGILINPSPLKGEYKVKIEGV
AIGKDSYIKEPSLIVAGKVYGILGTDNAKRDIWSGIVVGTKWAMLIGLMTSFISVSVGVIYGVTSAYFGGWVDSAMMRVF
EVFVSIPMLPVLIVVSAIFKPSIWLIILMMCIFYWTGPVRTVRSMGLQIKEETYIEAAKALNASNSRIIFKHMIPQLIPY
AFASMALSVPGAIVVEASLSLLGVGDTTIVTWGQILHGAHVNGAVLQGLWWWVIPPGLAIALMGMTFAFIGFSMDKILNP
KLKTR

Sequences:

>Translated_485_residues
MSNGNIPVKPGKGPDVKSSGWSDFKSSLGEFWQEFSRVKYGKWGLVLLAIFILMIIFSSQITPFKEAGTRWSDIEYWEDN
PQSAAPAWINWFSSQKRTEHEILRDPEWKVIDRGRMKTYSGSFTYNYQYDIPPDELIFKALSKGTVNMQVTLVRPDGEEI
RMTQASVNSRKEQKVRAPMANDAMFGAYRLASRFESRENLEKINKNSINPIKVIFSRGQEGILINPSPLKGEYKVKIEGV
AIGKDSYIKEPSLIVAGKVYGILGTDNAKRDIWSGIVVGTKWAMLIGLMTSFISVSVGVIYGVTSAYFGGWVDSAMMRVF
EVFVSIPMLPVLIVVSAIFKPSIWLIILMMCIFYWTGPVRTVRSMGLQIKEETYIEAAKALNASNSRIIFKHMIPQLIPY
AFASMALSVPGAIVVEASLSLLGVGDTTIVTWGQILHGAHVNGAVLQGLWWWVIPPGLAIALMGMTFAFIGFSMDKILNP
KLKTR
>Mature_484_residues
SNGNIPVKPGKGPDVKSSGWSDFKSSLGEFWQEFSRVKYGKWGLVLLAIFILMIIFSSQITPFKEAGTRWSDIEYWEDNP
QSAAPAWINWFSSQKRTEHEILRDPEWKVIDRGRMKTYSGSFTYNYQYDIPPDELIFKALSKGTVNMQVTLVRPDGEEIR
MTQASVNSRKEQKVRAPMANDAMFGAYRLASRFESRENLEKINKNSINPIKVIFSRGQEGILINPSPLKGEYKVKIEGVA
IGKDSYIKEPSLIVAGKVYGILGTDNAKRDIWSGIVVGTKWAMLIGLMTSFISVSVGVIYGVTSAYFGGWVDSAMMRVFE
VFVSIPMLPVLIVVSAIFKPSIWLIILMMCIFYWTGPVRTVRSMGLQIKEETYIEAAKALNASNSRIIFKHMIPQLIPYA
FASMALSVPGAIVVEASLSLLGVGDTTIVTWGQILHGAHVNGAVLQGLWWWVIPPGLAIALMGMTFAFIGFSMDKILNPK
LKTR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=222, Percent_Identity=28.8288288288288, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787760, Length=219, Percent_Identity=30.5936073059361, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1787498, Length=219, Percent_Identity=31.5068493150685, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788505, Length=163, Percent_Identity=33.1288343558282, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789964, Length=241, Percent_Identity=31.1203319502075, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789889, Length=240, Percent_Identity=25, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 54185; Mature: 54054

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGNIPVKPGKGPDVKSSGWSDFKSSLGEFWQEFSRVKYGKWGLVLLAIFILMIIFSSQ
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
ITPFKEAGTRWSDIEYWEDNPQSAAPAWINWFSSQKRTEHEILRDPEWKVIDRGRMKTYS
CCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCCEEECCCCCEEEC
GSFTYNYQYDIPPDELIFKALSKGTVNMQVTLVRPDGEEIRMTQASVNSRKEQKVRAPMA
CCEEEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCC
NDAMFGAYRLASRFESRENLEKINKNSINPIKVIFSRGQEGILINPSPLKGEYKVKIEGV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCCCCCEEEEEEEEE
AIGKDSYIKEPSLIVAGKVYGILGTDNAKRDIWSGIVVGTKWAMLIGLMTSFISVSVGVI
EECCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGVTSAYFGGWVDSAMMRVFEVFVSIPMLPVLIVVSAIFKPSIWLIILMMCIFYWTGPVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHH
TVRSMGLQIKEETYIEAAKALNASNSRIIFKHMIPQLIPYAFASMALSVPGAIVVEASLS
HHHHCCCEECHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECEE
LLGVGDTTIVTWGQILHGAHVNGAVLQGLWWWVIPPGLAIALMGMTFAFIGFSMDKILNP
EEECCCCHHEEHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
KLKTR
CCCCC
>Mature Secondary Structure 
SNGNIPVKPGKGPDVKSSGWSDFKSSLGEFWQEFSRVKYGKWGLVLLAIFILMIIFSSQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
ITPFKEAGTRWSDIEYWEDNPQSAAPAWINWFSSQKRTEHEILRDPEWKVIDRGRMKTYS
CCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCCEEECCCCCEEEC
GSFTYNYQYDIPPDELIFKALSKGTVNMQVTLVRPDGEEIRMTQASVNSRKEQKVRAPMA
CCEEEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCC
NDAMFGAYRLASRFESRENLEKINKNSINPIKVIFSRGQEGILINPSPLKGEYKVKIEGV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCCCCCEEEEEEEEE
AIGKDSYIKEPSLIVAGKVYGILGTDNAKRDIWSGIVVGTKWAMLIGLMTSFISVSVGVI
EECCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGVTSAYFGGWVDSAMMRVFEVFVSIPMLPVLIVVSAIFKPSIWLIILMMCIFYWTGPVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHH
TVRSMGLQIKEETYIEAAKALNASNSRIIFKHMIPQLIPYAFASMALSVPGAIVVEASLS
HHHHCCCEECHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECEE
LLGVGDTTIVTWGQILHGAHVNGAVLQGLWWWVIPPGLAIALMGMTFAFIGFSMDKILNP
EEECCCCHHEEHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
KLKTR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]