Click here to switch to the map view.

The map label for this gene is appB [H]

Identifier: 220932144

GI number: 220932144

Start: 1402241

End: 1403290

Strand: Reverse

Name: appB [H]

Synonym: Hore_13070

Alternate gene names: 220932144

Gene position: 1403290-1402241 (Counterclockwise)

Preceding gene: 220932145

Following gene: 220932143

Centisome position: 54.43

GC content: 42.29

Gene sequence:

>1050_bases
TTGTATGGACGATATGTCGTAAAGAGGATAATCTATGGGATAATTATCTATGTAGTGATAATATTTGTGCTTTCAATCCT
GTTTAATACCGTAATGGAAACCACTTTACGTTCCCAGATAGAAGAAAGAATTCAGGGAGAATTTATGTCAAGGGATATGG
CTCGTTTATCCCATGAAGAAGTCCAGCAATTAAAACAACAGCGGCGGGAAGAATTATATAATATGTATCACTTAAACGAA
CCTTATATTTATCGTGTCTTCTGGAGGGCGTATGATACTATAACCTTTGATTTCGGCAGGTCTACCCATATAAAATCTAA
TGCAGGTGAGAGAGAAGTTTTTACTATTGTTATGGAGAAATTACCGAGGACAGCTCTACTTTTTACCGTAGCTGCATTTA
TTAATGTTATAATCAGTATTTTAGTGGGATTGAAAAAAGCCCAGAAGGCCGGGGGGCTGATGGACCAGAGTACTTCCATT
TTGACCATGGTTGTCTGGGGTATGCCCACCTGGTGGCTGGGGATGATTTTAATTATGTTATTTGCCTATGTTATTCCTAT
TTTCCCGTCTGGAGGTATACATTCCACTCCACCTCCGGAAGGTGGTCTGGCTTATTTTTTTGACATGCTGTACCATATGA
CATTACCACTTTTAACCCTGGTTTTAATCAGGGTCTGGGGTGGTACCTACCTGACCCGTAATATTGTTCTGGGGACATTA
CAGCAGGATTATATTATGTCAGCCCGGGCCCGGGGAATATCAGAAAAACGGGTCCTGTATGGTCATGCTCTAAGGTCAGC
CGCTCCTCCTATTGCCACTATGTCTGTTATTTCCCTGCTCCGCTCCTTTGCTGGTGCTATCATTTTTGAAGGCATTTTTA
GCTGGCCGGGCATGGGGAATCTTTACTGGGTTGCTTTACAACAACACGATATACCGGTTTTGATGGGTAATCTGTCGGTA
ACCATCCTGTTATACCTGGCTGGACTGGTAGTCCTTGACCTGATTTACGGTTTCCTCGATCCCCGTATAAAGGTAGGTGG
TAAAGAATGA

Upstream 100 bases:

>100_bases
TACAAATATAATTAATTTCATTGTAGAAATTAAATATGCCCCCTGGTATTAAACAGGGGGCATAGTTTCTTTATTCTTTA
TGAAAGTAGAGGTGATAGCT

Downstream 100 bases:

>100_bases
GCAATGGAAATATTCCAGTAAAACCTGGTAAAGGACCAGATGTCAAGTCTTCAGGCTGGAGTGATTTTAAGTCTTCCCTG
GGAGAATTCTGGCAGGAATT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MYGRYVVKRIIYGIIIYVVIIFVLSILFNTVMETTLRSQIEERIQGEFMSRDMARLSHEEVQQLKQQRREELYNMYHLNE
PYIYRVFWRAYDTITFDFGRSTHIKSNAGEREVFTIVMEKLPRTALLFTVAAFINVIISILVGLKKAQKAGGLMDQSTSI
LTMVVWGMPTWWLGMILIMLFAYVIPIFPSGGIHSTPPPEGGLAYFFDMLYHMTLPLLTLVLIRVWGGTYLTRNIVLGTL
QQDYIMSARARGISEKRVLYGHALRSAAPPIATMSVISLLRSFAGAIIFEGIFSWPGMGNLYWVALQQHDIPVLMGNLSV
TILLYLAGLVVLDLIYGFLDPRIKVGGKE

Sequences:

>Translated_349_residues
MYGRYVVKRIIYGIIIYVVIIFVLSILFNTVMETTLRSQIEERIQGEFMSRDMARLSHEEVQQLKQQRREELYNMYHLNE
PYIYRVFWRAYDTITFDFGRSTHIKSNAGEREVFTIVMEKLPRTALLFTVAAFINVIISILVGLKKAQKAGGLMDQSTSI
LTMVVWGMPTWWLGMILIMLFAYVIPIFPSGGIHSTPPPEGGLAYFFDMLYHMTLPLLTLVLIRVWGGTYLTRNIVLGTL
QQDYIMSARARGISEKRVLYGHALRSAAPPIATMSVISLLRSFAGAIIFEGIFSWPGMGNLYWVALQQHDIPVLMGNLSV
TILLYLAGLVVLDLIYGFLDPRIKVGGKE
>Mature_349_residues
MYGRYVVKRIIYGIIIYVVIIFVLSILFNTVMETTLRSQIEERIQGEFMSRDMARLSHEEVQQLKQQRREELYNMYHLNE
PYIYRVFWRAYDTITFDFGRSTHIKSNAGEREVFTIVMEKLPRTALLFTVAAFINVIISILVGLKKAQKAGGLMDQSTSI
LTMVVWGMPTWWLGMILIMLFAYVIPIFPSGGIHSTPPPEGGLAYFFDMLYHMTLPLLTLVLIRVWGGTYLTRNIVLGTL
QQDYIMSARARGISEKRVLYGHALRSAAPPIATMSVISLLRSFAGAIIFEGIFSWPGMGNLYWVALQQHDIPVLMGNLSV
TILLYLAGLVVLDLIYGFLDPRIKVGGKE

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=301, Percent_Identity=31.2292358803987, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788504, Length=303, Percent_Identity=29.042904290429, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1787497, Length=286, Percent_Identity=26.5734265734266, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787761, Length=310, Percent_Identity=30, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789888, Length=272, Percent_Identity=26.1029411764706, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787053, Length=344, Percent_Identity=26.1627906976744, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787550, Length=275, Percent_Identity=24, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39737; Mature: 39737

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGRYVVKRIIYGIIIYVVIIFVLSILFNTVMETTLRSQIEERIQGEFMSRDMARLSHEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQQLKQQRREELYNMYHLNEPYIYRVFWRAYDTITFDFGRSTHIKSNAGEREVFTIVMEK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHH
LPRTALLFTVAAFINVIISILVGLKKAQKAGGLMDQSTSILTMVVWGMPTWWLGMILIML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
FAYVIPIFPSGGIHSTPPPEGGLAYFFDMLYHMTLPLLTLVLIRVWGGTYLTRNIVLGTL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QQDYIMSARARGISEKRVLYGHALRSAAPPIATMSVISLLRSFAGAIIFEGIFSWPGMGN
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LYWVALQQHDIPVLMGNLSVTILLYLAGLVVLDLIYGFLDPRIKVGGKE
EEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYGRYVVKRIIYGIIIYVVIIFVLSILFNTVMETTLRSQIEERIQGEFMSRDMARLSHEE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQQLKQQRREELYNMYHLNEPYIYRVFWRAYDTITFDFGRSTHIKSNAGEREVFTIVMEK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHH
LPRTALLFTVAAFINVIISILVGLKKAQKAGGLMDQSTSILTMVVWGMPTWWLGMILIML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
FAYVIPIFPSGGIHSTPPPEGGLAYFFDMLYHMTLPLLTLVLIRVWGGTYLTRNIVLGTL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QQDYIMSARARGISEKRVLYGHALRSAAPPIATMSVISLLRSFAGAIIFEGIFSWPGMGN
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LYWVALQQHDIPVLMGNLSVTILLYLAGLVVLDLIYGFLDPRIKVGGKE
EEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]