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The map label for this gene is comEA [H]

Identifier: 220932130

GI number: 220932130

Start: 1387305

End: 1388042

Strand: Reverse

Name: comEA [H]

Synonym: Hore_12930

Alternate gene names: 220932130

Gene position: 1388042-1387305 (Counterclockwise)

Preceding gene: 220932131

Following gene: 220932129

Centisome position: 53.84

GC content: 35.09

Gene sequence:

>738_bases
ATGTCAAAATTAAAAAAAGAGCAACTTCTTATAGTGTTATTTATATTGTTAACAATTATAATTGGTACAGGAATTTTAAT
TTACCAAAATACTACTGATTCTGTAATAATAGCTAAATTAGATGATGAATTAACTTCTGAAAAGCAATCACTGGCTGATG
GAAAAGATATAAAGGTTTCTACAGAAGAGGATGCAGAAAAAGAAAATAACGAAACTCTTGAGAAAGAAAAGAAAAAAATT
ATTGTTCATGTGGCCGGGGAAGTTAAAAACCCGGGGGTATATAAATTACCAGAGGATGCAAGGGTAATTGACGCTGTAAA
CGCAGCTGGTGGGACTACAGATGAGGCTGACCGGCATGCTGTAAATCTTGCTGCCCCTATTTATGATGGTGAAAAAATAG
TCATACCGGCCAAAATTAAGTCAAACAAGGGTGAAGACCCTGCTTTATTAAATGACATTACAGGGAGTAAACCAGTCAGC
GTATCCCGGAGCAGGGAAGAAGTCAATAAAAATAATGAGTTATTGATTACTGATAAATATCCTGAAAAAATTAATTTAAA
CCGGTCAAGTCAGGAACAATTACAAAAACTACCAGGAATAGGTCCCAGTAAGGCCAGGAGTATAGTAAAATACCGGGAAG
AAAACGGCTTTTTTACAGATAAGGCACAACTACTTAATGTTTCCGGGATTGGGGAGAAGACTTATGAAAAATTAAAAGAT
AAAGTGAGTTTAAGATGA

Upstream 100 bases:

>100_bases
AAAATATAAAAAAATTACTATAAATTGTATAAAAATAAAGGATAATAGAAATAAATGGTTAATTATTAAGTATAATCCCT
GATAAAGAAAGGTGATTTTA

Downstream 100 bases:

>100_bases
GATGAAATCAAGACCCCTTTTCTGGACGGCTTTATTTTTAATAATGGGAATCACCCTGGGTTATTTTATTAATATTAATA
TATATATTTTAATTGTTTTA

Product: competence protein ComEA helix-hairpin-helix repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSKLKKEQLLIVLFILLTIIIGTGILIYQNTTDSVIIAKLDDELTSEKQSLADGKDIKVSTEEDAEKENNETLEKEKKKI
IVHVAGEVKNPGVYKLPEDARVIDAVNAAGGTTDEADRHAVNLAAPIYDGEKIVIPAKIKSNKGEDPALLNDITGSKPVS
VSRSREEVNKNNELLITDKYPEKINLNRSSQEQLQKLPGIGPSKARSIVKYREENGFFTDKAQLLNVSGIGEKTYEKLKD
KVSLR

Sequences:

>Translated_245_residues
MSKLKKEQLLIVLFILLTIIIGTGILIYQNTTDSVIIAKLDDELTSEKQSLADGKDIKVSTEEDAEKENNETLEKEKKKI
IVHVAGEVKNPGVYKLPEDARVIDAVNAAGGTTDEADRHAVNLAAPIYDGEKIVIPAKIKSNKGEDPALLNDITGSKPVS
VSRSREEVNKNNELLITDKYPEKINLNRSSQEQLQKLPGIGPSKARSIVKYREENGFFTDKAQLLNVSGIGEKTYEKLKD
KVSLR
>Mature_244_residues
SKLKKEQLLIVLFILLTIIIGTGILIYQNTTDSVIIAKLDDELTSEKQSLADGKDIKVSTEEDAEKENNETLEKEKKKII
VHVAGEVKNPGVYKLPEDARVIDAVNAAGGTTDEADRHAVNLAAPIYDGEKIVIPAKIKSNKGEDPALLNDITGSKPVSV
SRSREEVNKNNELLITDKYPEKINLNRSSQEQLQKLPGIGPSKARSIVKYREENGFFTDKAQLLNVSGIGEKTYEKLKDK
VSLR

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 27066; Mature: 26935

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKKEQLLIVLFILLTIIIGTGILIYQNTTDSVIIAKLDDELTSEKQSLADGKDIKVS
CCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCEEEE
TEEDAEKENNETLEKEKKKIIVHVAGEVKNPGVYKLPEDARVIDAVNAAGGTTDEADRHA
CHHHHHHHCHHHHHHHHHEEEEEEECCCCCCCCEECCCCCHHHHHHHCCCCCCCCCCHHE
VNLAAPIYDGEKIVIPAKIKSNKGEDPALLNDITGSKPVSVSRSREEVNKNNELLITDKY
EEEEEEEECCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCCCEEEEECC
PEKINLNRSSQEQLQKLPGIGPSKARSIVKYREENGFFTDKAQLLNVSGIGEKTYEKLKD
CCEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECHHHEEEECCCCHHHHHHHHH
KVSLR
HHCCC
>Mature Secondary Structure 
SKLKKEQLLIVLFILLTIIIGTGILIYQNTTDSVIIAKLDDELTSEKQSLADGKDIKVS
CCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCEEEE
TEEDAEKENNETLEKEKKKIIVHVAGEVKNPGVYKLPEDARVIDAVNAAGGTTDEADRHA
CHHHHHHHCHHHHHHHHHEEEEEEECCCCCCCCEECCCCCHHHHHHHCCCCCCCCCCHHE
VNLAAPIYDGEKIVIPAKIKSNKGEDPALLNDITGSKPVSVSRSREEVNKNNELLITDKY
EEEEEEEECCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCCCEEEEECC
PEKINLNRSSQEQLQKLPGIGPSKARSIVKYREENGFFTDKAQLLNVSGIGEKTYEKLKD
CCEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECHHHEEEECCCCHHHHHHHHH
KVSLR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]