Click here to switch to the map view.

The map label for this gene is hemN [H]

Identifier: 220932120

GI number: 220932120

Start: 1376778

End: 1377935

Strand: Reverse

Name: hemN [H]

Synonym: Hore_12830

Alternate gene names: 220932120

Gene position: 1377935-1376778 (Counterclockwise)

Preceding gene: 220932121

Following gene: 220932119

Centisome position: 53.45

GC content: 36.44

Gene sequence:

>1158_bases
ATGATTAAATTAAAAGAATATGACAGGCCCTTTGGCCTATATATTCATTTCCCATTTTGCCTGCGTAAGTGTAGTTATTG
TGATTTTTACTCAATAAAATACACCCAGGAGTTTGCCAATAAATATGTTGAGTCTCTCCTAAAGGAAATTAAAATCTACA
GCAAAAAGATACCTACCAAAAAAATAAAGACCATTTATCTGGGCGGGGGTACCCCTGGCCTTTTTACTTATAACCAGCTT
TACAGGATATTTGATTTTATTTTTAATAATTTTTCTGTATCTGAAGAAGGTGAAATTACCCTGGAAGCCAATCCTGGCTC
CCTGACTTTAGAAAAAATAAAGTATTTTAAAAAGCTGGGTATTAATCGTCTGAGCCTTGGGGTCCAGAGTTTTGTGGAAG
ATGAACTCAAATTACTGGGCAGATTCCATAGTTCTAAGAAGGCCCGGGAGGTTCTGCTTTTAATAAACAGGGTTTTTGAT
AATTATAATACTGATTTAATCTTTGCCATACCTGGTCAGAGTATGGATAACTGGGAATATTCTTTGAAACAGATCCTGGA
ATTGAAACCACCCCATCTTTCCCTTTACAATCTTCAACTAGAAAAAGGAACTCTTCTTTATAAAAAGGTTAAAAAGGGAG
AAATTAAACCGGTCTCAGATGAAGTTGATGCCCGGATGTACTTAAAAGCGAAAAAGCAGCTGGGTAAAGCAGGTTACCTT
CATTATGAAATATCTAATTTTGCCAGACCGGGTTTTGAATCGAGACATAATATTCTCTACTGGAAGTATGAACCTTACCT
GGGGCTGGGACCGGCTGCCCATAGTTTTACCGGTAAAACCAGGTTTAATAATTATTCTAATCTCACCCCTTATATCAAAC
ACCTTGAAAATGGGGTGCTGCCTGTAGACAATACTGTAAGACTTGATAGAGAAGAAATGATGTCAGAGTATATCATTCTT
GGTCTCCGGCTGCGGAAAGGTATCTCTTTTAAGGAGTTTAAGGAATGCTTTGGTGTTGATTTAAAGGAAATTTATTATAA
TAAAATTACAGAACTAATTGAAAAGGATTTAATCCATATAAAAGGAGATAGGATACAGCTAACAGAAAAGGGTCTGTTGC
TGGGAAATCAGGTATTTGTAGAGTTTTTGCCGGCTTAA

Upstream 100 bases:

>100_bases
CTCCTGGAAAAGCAAAAAGAGGGTAAAAAACGGATGAAAAAGGTAGGTAAAGTTGAGATTCCCCAGAAAGCTTTTATGGC
AGTATTAGAGAGGAACGATG

Downstream 100 bases:

>100_bases
AATATTTGACAAAAAAAAATTAATATGTTATTTTAGTATTAGCTATTAGCACTCTGTAGGGTTGAGTGCTAAATAAGGGG
TGAACAGGATGGTTGACTTT

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MIKLKEYDRPFGLYIHFPFCLRKCSYCDFYSIKYTQEFANKYVESLLKEIKIYSKKIPTKKIKTIYLGGGTPGLFTYNQL
YRIFDFIFNNFSVSEEGEITLEANPGSLTLEKIKYFKKLGINRLSLGVQSFVEDELKLLGRFHSSKKAREVLLLINRVFD
NYNTDLIFAIPGQSMDNWEYSLKQILELKPPHLSLYNLQLEKGTLLYKKVKKGEIKPVSDEVDARMYLKAKKQLGKAGYL
HYEISNFARPGFESRHNILYWKYEPYLGLGPAAHSFTGKTRFNNYSNLTPYIKHLENGVLPVDNTVRLDREEMMSEYIIL
GLRLRKGISFKEFKECFGVDLKEIYYNKITELIEKDLIHIKGDRIQLTEKGLLLGNQVFVEFLPA

Sequences:

>Translated_385_residues
MIKLKEYDRPFGLYIHFPFCLRKCSYCDFYSIKYTQEFANKYVESLLKEIKIYSKKIPTKKIKTIYLGGGTPGLFTYNQL
YRIFDFIFNNFSVSEEGEITLEANPGSLTLEKIKYFKKLGINRLSLGVQSFVEDELKLLGRFHSSKKAREVLLLINRVFD
NYNTDLIFAIPGQSMDNWEYSLKQILELKPPHLSLYNLQLEKGTLLYKKVKKGEIKPVSDEVDARMYLKAKKQLGKAGYL
HYEISNFARPGFESRHNILYWKYEPYLGLGPAAHSFTGKTRFNNYSNLTPYIKHLENGVLPVDNTVRLDREEMMSEYIIL
GLRLRKGISFKEFKECFGVDLKEIYYNKITELIEKDLIHIKGDRIQLTEKGLLLGNQVFVEFLPA
>Mature_385_residues
MIKLKEYDRPFGLYIHFPFCLRKCSYCDFYSIKYTQEFANKYVESLLKEIKIYSKKIPTKKIKTIYLGGGTPGLFTYNQL
YRIFDFIFNNFSVSEEGEITLEANPGSLTLEKIKYFKKLGINRLSLGVQSFVEDELKLLGRFHSSKKAREVLLLINRVFD
NYNTDLIFAIPGQSMDNWEYSLKQILELKPPHLSLYNLQLEKGTLLYKKVKKGEIKPVSDEVDARMYLKAKKQLGKAGYL
HYEISNFARPGFESRHNILYWKYEPYLGLGPAAHSFTGKTRFNNYSNLTPYIKHLENGVLPVDNTVRLDREEMMSEYIIL
GLRLRKGISFKEFKECFGVDLKEIYYNKITELIEKDLIHIKGDRIQLTEKGLLLGNQVFVEFLPA

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=291, Percent_Identity=35.3951890034364, Blast_Score=197, Evalue=9e-51,
Organism=Escherichia coli, GI1789325, Length=390, Percent_Identity=31.7948717948718, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI87082341, Length=401, Percent_Identity=25.4364089775561, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 44983; Mature: 44983

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLKEYDRPFGLYIHFPFCLRKCSYCDFYSIKYTQEFANKYVESLLKEIKIYSKKIPTK
CCCCCCCCCCEEEEEECHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KIKTIYLGGGTPGLFTYNQLYRIFDFIFNNFSVSEEGEITLEANPGSLTLEKIKYFKKLG
CEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHC
INRLSLGVQSFVEDELKLLGRFHSSKKAREVLLLINRVFDNYNTDLIFAIPGQSMDNWEY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
SLKQILELKPPHLSLYNLQLEKGTLLYKKVKKGEIKPVSDEVDARMYLKAKKQLGKAGYL
HHHHHHHCCCCCEEEEEEEECCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
HYEISNFARPGFESRHNILYWKYEPYLGLGPAAHSFTGKTRFNNYSNLTPYIKHLENGVL
EEEHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
PVDNTVRLDREEMMSEYIILGLRLRKGISFKEFKECFGVDLKEIYYNKITELIEKDLIHI
CCCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEE
KGDRIQLTEKGLLLGNQVFVEFLPA
CCCEEEEECCCEEECCHHHHEECCC
>Mature Secondary Structure
MIKLKEYDRPFGLYIHFPFCLRKCSYCDFYSIKYTQEFANKYVESLLKEIKIYSKKIPTK
CCCCCCCCCCEEEEEECHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KIKTIYLGGGTPGLFTYNQLYRIFDFIFNNFSVSEEGEITLEANPGSLTLEKIKYFKKLG
CEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHC
INRLSLGVQSFVEDELKLLGRFHSSKKAREVLLLINRVFDNYNTDLIFAIPGQSMDNWEY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
SLKQILELKPPHLSLYNLQLEKGTLLYKKVKKGEIKPVSDEVDARMYLKAKKQLGKAGYL
HHHHHHHCCCCCEEEEEEEECCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
HYEISNFARPGFESRHNILYWKYEPYLGLGPAAHSFTGKTRFNNYSNLTPYIKHLENGVL
EEEHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
PVDNTVRLDREEMMSEYIILGLRLRKGISFKEFKECFGVDLKEIYYNKITELIEKDLIHI
CCCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEE
KGDRIQLTEKGLLLGNQVFVEFLPA
CCCEEEEECCCEEECCHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]