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The map label for this gene is hrcA [H]

Identifier: 220932119

GI number: 220932119

Start: 1375646

End: 1376689

Strand: Reverse

Name: hrcA [H]

Synonym: Hore_12820

Alternate gene names: 220932119

Gene position: 1376689-1375646 (Counterclockwise)

Preceding gene: 220932120

Following gene: 220932118

Centisome position: 53.4

GC content: 35.06

Gene sequence:

>1044_bases
ATGGTTGACTTTATTGATGATAGGAAAAGAAAGATATTAAAGGCCATCGTTCAGGAGCATATCCTGACTGCCGAACCGAT
CGGTTCCCGGACCCTGGCAAAAAACTATGAGTTTGGTGTTAGTTCAGCAACTATTAGAAATGAAATGTCTGATCTTGAGG
ATATGGGATATCTGGAGCAGCCATATACTTCTGCCGGTAGGGTTCCTTCAGATAAGGGTTACCGTTATTATGTTGATTCC
CTGATGGAAACCCGGGACTATCCTGAACAAGAAATTAGAAAAATGTTAGGGGAGTTTACTTTTGAACAGAATGTCCAGAC
TATAATGTCCAATCTGGCCCGGATGCTTTCCAGGTTAACGAGATATACTGCTGTTATCAGTGAACCTCAACTAAAAAAAA
GCAGGATAAGGGAAATTAAATTATTAAAGGTTTCCCGTAAAAATTTACTTATAGTTTTAGTGACAGATACCGGAATAGTG
AATAATAAAATAATAAGTCTTACTAAAGAAATATCTTCCAAACAATTAAGATACCTTAATGAGTTTTTTTCCCGAAAACT
ACAGAAAAGAGAGCTGAATACACTAGACGAAGGTTTTTTGAGTAAAATTGAAGAAGAATTACTGAACAGGTTAAAGATGT
CTGAACGTATAATAAAATTAATATTTGATGAAATGCTAAAAGTTGCTAAACCGGCTGAACTCAAGGTTCATCTCGGGGGA
ACTTCATATATTTTGGAACAGCCAGAATTTAACAATCTTGAGAATCTAAAAAAGGTTTTAAATATACTTGACCATGAAGA
AATACTTGGTAAATTACTTAATAGTTTTTCTGATAATGAATTAAAAGTTGTAATTGGACATGAAAACCAGCTGGAAGAAA
TGCATAAATGCAGTATTGTTATAGCTACCTATTGTATAGGTGATAAACCGCTGGGCAAACTGGGGGTAATTGGTCCTACA
AGGATGCATTATCCCATGGTAGTTTCTACAGTAAATTCACTTTCAAAAATTGTTGGCAAAATAATATCTAGAATGGATGG
GTGA

Upstream 100 bases:

>100_bases
TTGCCGGCTTAAAATATTTGACAAAAAAAAATTAATATGTTATTTTAGTATTAGCTATTAGCACTCTGTAGGGTTGAGTG
CTAAATAAGGGGTGAACAGG

Downstream 100 bases:

>100_bases
TGTGTCATGGAAAAAGAAAAGCATGTAAGTTCTAATGAAGAATTTAACGAAAAGGAAGAAAAAAATAACGTTGAAACAGT
GAGAAATAATGAAAATAATG

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MVDFIDDRKRKILKAIVQEHILTAEPIGSRTLAKNYEFGVSSATIRNEMSDLEDMGYLEQPYTSAGRVPSDKGYRYYVDS
LMETRDYPEQEIRKMLGEFTFEQNVQTIMSNLARMLSRLTRYTAVISEPQLKKSRIREIKLLKVSRKNLLIVLVTDTGIV
NNKIISLTKEISSKQLRYLNEFFSRKLQKRELNTLDEGFLSKIEEELLNRLKMSERIIKLIFDEMLKVAKPAELKVHLGG
TSYILEQPEFNNLENLKKVLNILDHEEILGKLLNSFSDNELKVVIGHENQLEEMHKCSIVIATYCIGDKPLGKLGVIGPT
RMHYPMVVSTVNSLSKIVGKIISRMDG

Sequences:

>Translated_347_residues
MVDFIDDRKRKILKAIVQEHILTAEPIGSRTLAKNYEFGVSSATIRNEMSDLEDMGYLEQPYTSAGRVPSDKGYRYYVDS
LMETRDYPEQEIRKMLGEFTFEQNVQTIMSNLARMLSRLTRYTAVISEPQLKKSRIREIKLLKVSRKNLLIVLVTDTGIV
NNKIISLTKEISSKQLRYLNEFFSRKLQKRELNTLDEGFLSKIEEELLNRLKMSERIIKLIFDEMLKVAKPAELKVHLGG
TSYILEQPEFNNLENLKKVLNILDHEEILGKLLNSFSDNELKVVIGHENQLEEMHKCSIVIATYCIGDKPLGKLGVIGPT
RMHYPMVVSTVNSLSKIVGKIISRMDG
>Mature_347_residues
MVDFIDDRKRKILKAIVQEHILTAEPIGSRTLAKNYEFGVSSATIRNEMSDLEDMGYLEQPYTSAGRVPSDKGYRYYVDS
LMETRDYPEQEIRKMLGEFTFEQNVQTIMSNLARMLSRLTRYTAVISEPQLKKSRIREIKLLKVSRKNLLIVLVTDTGIV
NNKIISLTKEISSKQLRYLNEFFSRKLQKRELNTLDEGFLSKIEEELLNRLKMSERIIKLIFDEMLKVAKPAELKVHLGG
TSYILEQPEFNNLENLKKVLNILDHEEILGKLLNSFSDNELKVVIGHENQLEEMHKCSIVIATYCIGDKPLGKLGVIGPT
RMHYPMVVSTVNSLSKIVGKIISRMDG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39876; Mature: 39876

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDFIDDRKRKILKAIVQEHILTAEPIGSRTLAKNYEFGVSSATIRNEMSDLEDMGYLEQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
PYTSAGRVPSDKGYRYYVDSLMETRDYPEQEIRKMLGEFTFEQNVQTIMSNLARMLSRLT
CCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYTAVISEPQLKKSRIREIKLLKVSRKNLLIVLVTDTGIVNNKIISLTKEISSKQLRYLN
HHHHHHCCCHHHHHHHHHHHHHEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
EFFSRKLQKRELNTLDEGFLSKIEEELLNRLKMSERIIKLIFDEMLKVAKPAELKVHLGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
TSYILEQPEFNNLENLKKVLNILDHEEILGKLLNSFSDNELKVVIGHENQLEEMHKCSIV
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHH
IATYCIGDKPLGKLGVIGPTRMHYPMVVSTVNSLSKIVGKIISRMDG
HHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVDFIDDRKRKILKAIVQEHILTAEPIGSRTLAKNYEFGVSSATIRNEMSDLEDMGYLEQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
PYTSAGRVPSDKGYRYYVDSLMETRDYPEQEIRKMLGEFTFEQNVQTIMSNLARMLSRLT
CCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYTAVISEPQLKKSRIREIKLLKVSRKNLLIVLVTDTGIVNNKIISLTKEISSKQLRYLN
HHHHHHCCCHHHHHHHHHHHHHEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
EFFSRKLQKRELNTLDEGFLSKIEEELLNRLKMSERIIKLIFDEMLKVAKPAELKVHLGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
TSYILEQPEFNNLENLKKVLNILDHEEILGKLLNSFSDNELKVVIGHENQLEEMHKCSIV
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHH
IATYCIGDKPLGKLGVIGPTRMHYPMVVSTVNSLSKIVGKIISRMDG
HHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA