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The map label for this gene is ruvA

Identifier: 220932069

GI number: 220932069

Start: 1325973

End: 1326557

Strand: Reverse

Name: ruvA

Synonym: Hore_12320

Alternate gene names: 220932069

Gene position: 1326557-1325973 (Counterclockwise)

Preceding gene: 220932070

Following gene: 220932068

Centisome position: 51.45

GC content: 36.92

Gene sequence:

>585_bases
GTGATAGGTTATCTAAAAGGGAATGTTATCTGGAAGGCTGAAAATAAAGTAATTCTGGAGACAGGAGGGGTAGGTTATCG
GGTTTTAGTACCATCTACTGTCAGGCTAAAACCGGTAGGAGAAAAATTAGAACTTTTTGTATATACCTATGTTAGAGAAG
ATAGTCTTGACCTGTATGGATTTAAAACCATGGAAGAACGAGAACTATTTGAAACATTGTTATCTGTATCGGGGATTGGA
CCCCGGGCTGCTATAAATATTTTATCATCCCTTTCCTATAAAAAATTTATAGAGGCTATTTTAACTGAAAAAGTTAGTAT
ATTAAAGCAGGTTTCAGGGATTGGCCCCAAGACGGCAAAAAGATTAATACTTGAGCTCAAGGGTAAATTAAAAGATATGA
GTGGGGATTTTGAAGAACCCCTTCCTGATAATAGAAATACAGAATTATCTGATGCCCTGGCTTCCCTGGGTTATTCAGAG
CTTGAAATTGAAGAAGCCTTAAGTAACGCTGATATAAAAAATAATGGCAGCCTTGAAGAAAATATCAAAAAGGCATTAGG
GTACCTTGGTAGTAAGGGGAGTTAG

Upstream 100 bases:

>100_bases
TAAACGAAATACCAAAACCTGATGATGTAGCTGATGCCCTGGCTATTTCTATTTGCCATGGAAACAGTTACCGCTTAAAT
CGGAAATGGGGGACAAAAGG

Downstream 100 bases:

>100_bases
TCATGGATTTAGAAAATAGAATTATTTCACCAGAAAAAAAAGAAGATGATATGGCTCTTGACAGGAGTTTAAGGCCTGAA
AGGCTTAATAACTTTATTGG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIGYLKGNVIWKAENKVILETGGVGYRVLVPSTVRLKPVGEKLELFVYTYVREDSLDLYGFKTMEERELFETLLSVSGIG
PRAAINILSSLSYKKFIEAILTEKVSILKQVSGIGPKTAKRLILELKGKLKDMSGDFEEPLPDNRNTELSDALASLGYSE
LEIEEALSNADIKNNGSLEENIKKALGYLGSKGS

Sequences:

>Translated_194_residues
MIGYLKGNVIWKAENKVILETGGVGYRVLVPSTVRLKPVGEKLELFVYTYVREDSLDLYGFKTMEERELFETLLSVSGIG
PRAAINILSSLSYKKFIEAILTEKVSILKQVSGIGPKTAKRLILELKGKLKDMSGDFEEPLPDNRNTELSDALASLGYSE
LEIEEALSNADIKNNGSLEENIKKALGYLGSKGS
>Mature_194_residues
MIGYLKGNVIWKAENKVILETGGVGYRVLVPSTVRLKPVGEKLELFVYTYVREDSLDLYGFKTMEERELFETLLSVSGIG
PRAAINILSSLSYKKFIEAILTEKVSILKQVSGIGPKTAKRLILELKGKLKDMSGDFEEPLPDNRNTELSDALASLGYSE
LEIEEALSNADIKNNGSLEENIKKALGYLGSKGS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=200, Percent_Identity=37.5, Blast_Score=123, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_HALOH (B8CXG3)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508977.1
- ProteinModelPortal:   B8CXG3
- SMR:   B8CXG3
- GeneID:   7313933
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_12320
- HOGENOM:   HBG635309
- OMA:   FRERILF
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21392; Mature: 21392

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGYLKGNVIWKAENKVILETGGVGYRVLVPSTVRLKPVGEKLELFVYTYVREDSLDLYG
CCCEEECCEEEEECCEEEEEECCCEEEEECCCCEEEEECCCCEEEEEEEEEECCCCCEEC
FKTMEERELFETLLSVSGIGPRAAINILSSLSYKKFIEAILTEKVSILKQVSGIGPKTAK
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLILELKGKLKDMSGDFEEPLPDNRNTELSDALASLGYSELEIEEALSNADIKNNGSLEE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHH
NIKKALGYLGSKGS
HHHHHHHHCCCCCC
>Mature Secondary Structure
MIGYLKGNVIWKAENKVILETGGVGYRVLVPSTVRLKPVGEKLELFVYTYVREDSLDLYG
CCCEEECCEEEEECCEEEEEECCCEEEEECCCCEEEEECCCCEEEEEEEEEECCCCCEEC
FKTMEERELFETLLSVSGIGPRAAINILSSLSYKKFIEAILTEKVSILKQVSGIGPKTAK
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RLILELKGKLKDMSGDFEEPLPDNRNTELSDALASLGYSELEIEEALSNADIKNNGSLEE
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHH
NIKKALGYLGSKGS
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA