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The map label for this gene is mrpC [H]

Identifier: 220932044

GI number: 220932044

Start: 1303009

End: 1303341

Strand: Reverse

Name: mrpC [H]

Synonym: Hore_12070

Alternate gene names: 220932044

Gene position: 1303341-1303009 (Counterclockwise)

Preceding gene: 220932045

Following gene: 220932043

Centisome position: 50.55

GC content: 36.94

Gene sequence:

>333_bases
GTGTTATATCACCTGGTGTTTATCCTGCTATTCATGTTGGGCTTTTATACATTACTAACTAAAAAGAATTTAATAAAGAT
AGTTATCGGATTAAATATCATGGAAGCTTCGGTCCTCTTCTGGTTAATAGCTATTTCTGACCGTGGAAAAGCGCCAATTA
TGAATATGGAAGATATGGTCGAAAAGGTAAGTGATCCCTTGCCTCAGGCTTTAGCCCTGACAGCAATTGTTATCGGGGCC
AGTACGACTGCTTTATTATTGACCTTAATTATTGAATTAAGTAAACATCGGGATACAGTTAACATTGATGAATTAAAGGG
GCTGGATGACTAA

Upstream 100 bases:

>100_bases
AGTATTCCCCTGATTAATATAAGTATAGGTTTTAAAGTCGGGGCCGGACTTGCTATTATGTTTTATAGTATGATCCAGAA
AACCTTTGAGGAGGATTAAA

Downstream 100 bases:

>100_bases
TGTCTTTGTCAATATTAATGTTAATCATAATACCCCTGTCTACTGCCTTTTTAATTCCATTAATTGATATCATAAATAAG
CGTCTGAGAAAATACCTCGT

Product: NADH dehydrogenase I subunit K

Products: NAD+; ubiquinol

Alternate protein names: Mrp complex subunit C; Multiple resistance and pH homeostasis protein C [H]

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MLYHLVFILLFMLGFYTLLTKKNLIKIVIGLNIMEASVLFWLIAISDRGKAPIMNMEDMVEKVSDPLPQALALTAIVIGA
STTALLLTLIIELSKHRDTVNIDELKGLDD

Sequences:

>Translated_110_residues
MLYHLVFILLFMLGFYTLLTKKNLIKIVIGLNIMEASVLFWLIAISDRGKAPIMNMEDMVEKVSDPLPQALALTAIVIGA
STTALLLTLIIELSKHRDTVNIDELKGLDD
>Mature_110_residues
MLYHLVFILLFMLGFYTLLTKKNLIKIVIGLNIMEASVLFWLIAISDRGKAPIMNMEDMVEKVSDPLPQALALTAIVIGA
STTALLLTLIIELSKHRDTVNIDELKGLDD

Specific function: Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential, and is thus inferred to be electrogenic. Does not transport K(+), Ca(2+) or Mg(2+

COG id: COG1006

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhC subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001133 [H]

Pfam domain/function: PF00420 Oxidored_q2 [H]

EC number: 1.6.5.3

Molecular weight: Translated: 12256; Mature: 12256

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHLVFILLFMLGFYTLLTKKNLIKIVIGLNIMEASVLFWLIAISDRGKAPIMNMEDMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
EKVSDPLPQALALTAIVIGASTTALLLTLIIELSKHRDTVNIDELKGLDD
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
>Mature Secondary Structure
MLYHLVFILLFMLGFYTLLTKKNLIKIVIGLNIMEASVLFWLIAISDRGKAPIMNMEDMV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
EKVSDPLPQALALTAIVIGASTTALLLTLIIELSKHRDTVNIDELKGLDD
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]