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The map label for this gene is nuoN [H]

Identifier: 220932043

GI number: 220932043

Start: 1301489

End: 1303009

Strand: Reverse

Name: nuoN [H]

Synonym: Hore_12060

Alternate gene names: 220932043

Gene position: 1303009-1301489 (Counterclockwise)

Preceding gene: 220932044

Following gene: 220932042

Centisome position: 50.54

GC content: 35.63

Gene sequence:

>1521_bases
ATGTCTTTGTCAATATTAATGTTAATCATAATACCCCTGTCTACTGCCTTTTTAATTCCATTAATTGATATCATAAATAA
GCGTCTGAGAAAATACCTCGTAGTCGGTGTCTCGTTTCTGGAAGTAATATTGATTGGAAGAATTATTATTGATTACAGGG
TTGAAGGCTATAAGGATTATTTTAGTTATTATTTACTGGGAGGATGGGGTCCTGAAATAGGAATTAATATTGCCGTTGAT
GGACTGGGATTATTTTTCACCATCCTGATTAATATAGCCATGTTTTTAATTATTTTATATTCGATTGGTTTTATAGGTCA
CCATGAGGGCAAATATTATGTGCTGCTCTTTTTACTCTTTGCTGCTATGCAGGGTGTAGTTTTAACTGGTGATATATTTA
ATCAGTATGTATTTATAGAATTAATAACGGTAGCATCGGCTCCTCTGGTGGCGTTTACCAGGACCGAAAAGGGGACAGAG
GCAGGAATAAAATACTTAATATATGGTATTATCAGTGGTCTGTTATTTTTCATTGGAATAGTTATAATATACCAGACTAC
CGGGGCTTTGAACATGGCTATAGTGGCTGATAGATTTAAGCATATACCTTTAACCACCAGAAATTTTATTAAAGTTATTT
TCCTTACAAGTTTATTGATAAAATTGGGGGTATTCCCATTTCATTTCTGGCTGGCCAAAGCCCACAGTGCCTGTCCCAGT
TCTATAAGTGCTCTCCTATCAGGTTTACTATTGAAGGTTTATATCTATGTTTTCATCAGGTTGTTCTGGACGGTTTTTGG
AATAAACCAGGGTGATAAACTTTTACCGGTTATAATTTATATGGCTCTGGTATCATCCCTGCTGGGTCATATTTTTGCCT
TGCAGGAAGAGGATATAAAGAGAGTACTTGCCTTTTCAAGTATAGCCCATACAGGTATTATTATTGGTTCCCTGTTTCTG
GGGAGTATTTCAGGTGTCTACGGAGGGTTAATACATGTAATAAGCCATTTAACTATGAAAATAACACTTTTCCTGGGGGT
TGGATATTTATTAAAGTTTACCTCAGAACACAGGATAAAAAAGTTAAAGGGGATAGCTTATATTAACCCCCCTGTTACCT
TAAGTATTTTTACAGCCGGACTGGCTATGATTGGTATACCTCCACTGAATGGGTTTTATGGTAAATGGTTTATCTTAAAA
GCTTTTCTGGAAAAAGGCCATTACTTTGGGGCTTTTGTTGTTCTTTTTGGAAGCTTTCTGTCAGTTATCTATTATCTCAG
GATTTATAAATACATGATTACCAGAGTAAACGTAGATTATAATGAAAATAATATTTTTGAAACCAGTGTTCTGTTTCCAG
GATTTCACCGGGAGCAAGCTGTTGTAATGGTTGTGCTAATATTTTTTGGATTAGTAGTTTTATCTGGTTTTTTTTATTAC
AGATTTGATGGCCCATTGCTGGGTGCTGCTGAAGCATTACTTGATAATGGCAAATACATTAGCCAGCTGCTGGGGAGATA
A

Upstream 100 bases:

>100_bases
TCGGGGCCAGTACGACTGCTTTATTATTGACCTTAATTATTGAATTAAGTAAACATCGGGATACAGTTAACATTGATGAA
TTAAAGGGGCTGGATGACTA

Downstream 100 bases:

>100_bases
ATCATGATTCCATTAATGGATTTAATTGATATTACTAATATAAATATGTACCTCGCATTGACCGCTTTTATTATTAATAT
GCTAACAATTGTAGCCGGGT

Product: NADH dehydrogenase I subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSLSILMLIIIPLSTAFLIPLIDIINKRLRKYLVVGVSFLEVILIGRIIIDYRVEGYKDYFSYYLLGGWGPEIGINIAVD
GLGLFFTILINIAMFLIILYSIGFIGHHEGKYYVLLFLLFAAMQGVVLTGDIFNQYVFIELITVASAPLVAFTRTEKGTE
AGIKYLIYGIISGLLFFIGIVIIYQTTGALNMAIVADRFKHIPLTTRNFIKVIFLTSLLIKLGVFPFHFWLAKAHSACPS
SISALLSGLLLKVYIYVFIRLFWTVFGINQGDKLLPVIIYMALVSSLLGHIFALQEEDIKRVLAFSSIAHTGIIIGSLFL
GSISGVYGGLIHVISHLTMKITLFLGVGYLLKFTSEHRIKKLKGIAYINPPVTLSIFTAGLAMIGIPPLNGFYGKWFILK
AFLEKGHYFGAFVVLFGSFLSVIYYLRIYKYMITRVNVDYNENNIFETSVLFPGFHREQAVVMVVLIFFGLVVLSGFFYY
RFDGPLLGAAEALLDNGKYISQLLGR

Sequences:

>Translated_506_residues
MSLSILMLIIIPLSTAFLIPLIDIINKRLRKYLVVGVSFLEVILIGRIIIDYRVEGYKDYFSYYLLGGWGPEIGINIAVD
GLGLFFTILINIAMFLIILYSIGFIGHHEGKYYVLLFLLFAAMQGVVLTGDIFNQYVFIELITVASAPLVAFTRTEKGTE
AGIKYLIYGIISGLLFFIGIVIIYQTTGALNMAIVADRFKHIPLTTRNFIKVIFLTSLLIKLGVFPFHFWLAKAHSACPS
SISALLSGLLLKVYIYVFIRLFWTVFGINQGDKLLPVIIYMALVSSLLGHIFALQEEDIKRVLAFSSIAHTGIIIGSLFL
GSISGVYGGLIHVISHLTMKITLFLGVGYLLKFTSEHRIKKLKGIAYINPPVTLSIFTAGLAMIGIPPLNGFYGKWFILK
AFLEKGHYFGAFVVLFGSFLSVIYYLRIYKYMITRVNVDYNENNIFETSVLFPGFHREQAVVMVVLIFFGLVVLSGFFYY
RFDGPLLGAAEALLDNGKYISQLLGR
>Mature_505_residues
SLSILMLIIIPLSTAFLIPLIDIINKRLRKYLVVGVSFLEVILIGRIIIDYRVEGYKDYFSYYLLGGWGPEIGINIAVDG
LGLFFTILINIAMFLIILYSIGFIGHHEGKYYVLLFLLFAAMQGVVLTGDIFNQYVFIELITVASAPLVAFTRTEKGTEA
GIKYLIYGIISGLLFFIGIVIIYQTTGALNMAIVADRFKHIPLTTRNFIKVIFLTSLLIKLGVFPFHFWLAKAHSACPSS
ISALLSGLLLKVYIYVFIRLFWTVFGINQGDKLLPVIIYMALVSSLLGHIFALQEEDIKRVLAFSSIAHTGIIIGSLFLG
SISGVYGGLIHVISHLTMKITLFLGVGYLLKFTSEHRIKKLKGIAYINPPVTLSIFTAGLAMIGIPPLNGFYGKWFILKA
FLEKGHYFGAFVVLFGSFLSVIYYLRIYKYMITRVNVDYNENNIFETSVLFPGFHREQAVVMVVLIFFGLVVLSGFFYYR
FDGPLLGAAEALLDNGKYISQLLGR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=226, Percent_Identity=25.2212389380531, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI251831116, Length=212, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1788827, Length=349, Percent_Identity=28.080229226361, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788831, Length=353, Percent_Identity=29.4617563739377, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788613, Length=365, Percent_Identity=26.8493150684932, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788829, Length=316, Percent_Identity=27.5316455696203, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI2367154, Length=369, Percent_Identity=24.9322493224932, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI145693160, Length=369, Percent_Identity=25.7452574525745, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788614, Length=411, Percent_Identity=25.5474452554745, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 56664; Mature: 56533

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSILMLIIIPLSTAFLIPLIDIINKRLRKYLVVGVSFLEVILIGRIIIDYRVEGYKDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FSYYLLGGWGPEIGINIAVDGLGLFFTILINIAMFLIILYSIGFIGHHEGKYYVLLFLLF
HHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AAMQGVVLTGDIFNQYVFIELITVASAPLVAFTRTEKGTEAGIKYLIYGIISGLLFFIGI
HHHCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
VIIYQTTGALNMAIVADRFKHIPLTTRNFIKVIFLTSLLIKLGVFPFHFWLAKAHSACPS
HHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SISALLSGLLLKVYIYVFIRLFWTVFGINQGDKLLPVIIYMALVSSLLGHIFALQEEDIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVLAFSSIAHTGIIIGSLFLGSISGVYGGLIHVISHLTMKITLFLGVGYLLKFTSEHRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLKGIAYINPPVTLSIFTAGLAMIGIPPLNGFYGKWFILKAFLEKGHYFGAFVVLFGSFL
HHCCCEEECCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SVIYYLRIYKYMITRVNVDYNENNIFETSVLFPGFHREQAVVMVVLIFFGLVVLSGFFYY
HHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHEE
RFDGPLLGAAEALLDNGKYISQLLGR
EECCCHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
SLSILMLIIIPLSTAFLIPLIDIINKRLRKYLVVGVSFLEVILIGRIIIDYRVEGYKDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FSYYLLGGWGPEIGINIAVDGLGLFFTILINIAMFLIILYSIGFIGHHEGKYYVLLFLLF
HHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AAMQGVVLTGDIFNQYVFIELITVASAPLVAFTRTEKGTEAGIKYLIYGIISGLLFFIGI
HHHCCEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
VIIYQTTGALNMAIVADRFKHIPLTTRNFIKVIFLTSLLIKLGVFPFHFWLAKAHSACPS
HHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SISALLSGLLLKVYIYVFIRLFWTVFGINQGDKLLPVIIYMALVSSLLGHIFALQEEDIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVLAFSSIAHTGIIIGSLFLGSISGVYGGLIHVISHLTMKITLFLGVGYLLKFTSEHRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLKGIAYINPPVTLSIFTAGLAMIGIPPLNGFYGKWFILKAFLEKGHYFGAFVVLFGSFL
HHCCCEEECCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SVIYYLRIYKYMITRVNVDYNENNIFETSVLFPGFHREQAVVMVVLIFFGLVVLSGFFYY
HHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHEE
RFDGPLLGAAEALLDNGKYISQLLGR
EECCCHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA