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The map label for this gene is cinA

Identifier: 220932029

GI number: 220932029

Start: 1286491

End: 1287732

Strand: Reverse

Name: cinA

Synonym: Hore_11920

Alternate gene names: 220932029

Gene position: 1287732-1286491 (Counterclockwise)

Preceding gene: 220932030

Following gene: 220932028

Centisome position: 49.95

GC content: 37.6

Gene sequence:

>1242_bases
GTGATAGCTGAAATAATCTCAATAGGAACAGAATTACTCCATGGTGATATTGTCGATACCAATTCGGCTTACCTGGCTGA
AAAATTAACAGGCTGTGGTATAGATGTTCATTATATTAGCACAGTTGGTGATAATAAACAGAGGTTATATAAAACTTTAC
AACAGGCTGTCGAGAGAGCAGATTTGATTATTACCACTGGTGGTCTTGGTCCAACGATGGATGACCTGACCCGGGAAGCT
ATATCAGAAATAACAACTTGTCCTTTAGTAATGAGGCCAGACCTTGTTATTGATATTGAAGGTTATTTCAATCATAAAAG
AACGACAATGACTCCCAATAACCTGAAACAATCGTATCTTCCTGAAGGGGCAATACCGATAAATAATCCTGTTGGTACTG
CTCCTGGAATATTACTTGAGAAAGATAATTATATTATTATATCTTTGCCCGGGGTACCGCGGGAAATGAAGATAATGTTT
GAAGAAAGTGTCCTGCCATATATTAAGAAAAAAAATAATTTAATGATTATATCTAAGGAACTACATTTTATTGGAATAGG
GGAGTCTACCCTGGAAACAAAGCTAGAAGATATTATGGATTCTATGAACCCTTCCCTGGCATTATTAGCCGGGGATGGAG
AAGTAAAATTAAAAATTACCGGTAAAGGAAGAACGAAGAAAAAAATAGAAAATAAAATATCAGAAATAGTCAAAACTGTC
AGGAATAGAGTGGGAGAATATATTTACGGAGAAGACGAGACAAGTTTACCGGATGAAATAGGTAAATTATTATCAAAAAG
AGGGGTTACCATAGCCCTGGCTGAGTCATGTACTGGGGGACTGATTGGGGCAAGAATTACAGATATACCGGGGAGTTCAG
CATATTTTAAAGGAGGAGTCATTGCCTACAGTAATGAAGTTAAGATTAATCATCTCGGAGTTAATAAAAATACAATTAAT
AAAGAGGGGGCTGTTAGTCCGGAAACTGCAGCTGAAATGGCTAGTGGAGTTCGCCAGAGATTGGAGGCTGACATTGGACT
TAGTGTCACCGGTATTGCTGGTCCTGAAGGGGGTACAGATGAAAAACCGGTAGGCCTGGTGTACGTCGGTCTGGCCGGGA
TTGATGGTGAGGTAAAAACATATAAATTAAATTTTAAAGGTGATCGTAATAAAAACAGGTGGTTAACTACTCAGTCTGCT
TTTTATTATTTATACCGGTATCTTAAATTTTCTTTTAAATGA

Upstream 100 bases:

>100_bases
TAGAGGTTATTTAATTTTTTTAGTATAACTAAATTATTAAAGAACTTGTTAATAACTTTTTTCAGTGTTATAAGCTATGG
AAAAAGAAAGGGGACAGTAA

Downstream 100 bases:

>100_bases
CAGGGAAGTTGTCATCTGAAAGAGTTTTTTATTATTAATGTTTTAACAATATATTTTTGAGAGGATTATATCCAGGGGGG
CATGTTGATGAAAAGAAAGT

Product: competence/damage-inducible protein CinA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MIAEIISIGTELLHGDIVDTNSAYLAEKLTGCGIDVHYISTVGDNKQRLYKTLQQAVERADLIITTGGLGPTMDDLTREA
ISEITTCPLVMRPDLVIDIEGYFNHKRTTMTPNNLKQSYLPEGAIPINNPVGTAPGILLEKDNYIIISLPGVPREMKIMF
EESVLPYIKKKNNLMIISKELHFIGIGESTLETKLEDIMDSMNPSLALLAGDGEVKLKITGKGRTKKKIENKISEIVKTV
RNRVGEYIYGEDETSLPDEIGKLLSKRGVTIALAESCTGGLIGARITDIPGSSAYFKGGVIAYSNEVKINHLGVNKNTIN
KEGAVSPETAAEMASGVRQRLEADIGLSVTGIAGPEGGTDEKPVGLVYVGLAGIDGEVKTYKLNFKGDRNKNRWLTTQSA
FYYLYRYLKFSFK

Sequences:

>Translated_413_residues
MIAEIISIGTELLHGDIVDTNSAYLAEKLTGCGIDVHYISTVGDNKQRLYKTLQQAVERADLIITTGGLGPTMDDLTREA
ISEITTCPLVMRPDLVIDIEGYFNHKRTTMTPNNLKQSYLPEGAIPINNPVGTAPGILLEKDNYIIISLPGVPREMKIMF
EESVLPYIKKKNNLMIISKELHFIGIGESTLETKLEDIMDSMNPSLALLAGDGEVKLKITGKGRTKKKIENKISEIVKTV
RNRVGEYIYGEDETSLPDEIGKLLSKRGVTIALAESCTGGLIGARITDIPGSSAYFKGGVIAYSNEVKINHLGVNKNTIN
KEGAVSPETAAEMASGVRQRLEADIGLSVTGIAGPEGGTDEKPVGLVYVGLAGIDGEVKTYKLNFKGDRNKNRWLTTQSA
FYYLYRYLKFSFK
>Mature_413_residues
MIAEIISIGTELLHGDIVDTNSAYLAEKLTGCGIDVHYISTVGDNKQRLYKTLQQAVERADLIITTGGLGPTMDDLTREA
ISEITTCPLVMRPDLVIDIEGYFNHKRTTMTPNNLKQSYLPEGAIPINNPVGTAPGILLEKDNYIIISLPGVPREMKIMF
EESVLPYIKKKNNLMIISKELHFIGIGESTLETKLEDIMDSMNPSLALLAGDGEVKLKITGKGRTKKKIENKISEIVKTV
RNRVGEYIYGEDETSLPDEIGKLLSKRGVTIALAESCTGGLIGARITDIPGSSAYFKGGVIAYSNEVKINHLGVNKNTIN
KEGAVSPETAAEMASGVRQRLEADIGLSVTGIAGPEGGTDEKPVGLVYVGLAGIDGEVKTYKLNFKGDRNKNRWLTTQSA
FYYLYRYLKFSFK

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=286, Percent_Identity=33.9160839160839, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789052, Length=153, Percent_Identity=43.7908496732026, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1787818, Length=148, Percent_Identity=29.0540540540541, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71993974, Length=271, Percent_Identity=26.1992619926199, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993966, Length=271, Percent_Identity=26.1992619926199, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323832, Length=276, Percent_Identity=28.9855072463768, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINA_HALOH (B8CXC3)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508937.1
- ProteinModelPortal:   B8CXC3
- GeneID:   7313890
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_11920
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 45155; Mature: 45155

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAEIISIGTELLHGDIVDTNSAYLAEKLTGCGIDVHYISTVGDNKQRLYKTLQQAVERA
CHHHHHHHHHHHHCCCEECCCCHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHC
DLIITTGGLGPTMDDLTREAISEITTCPLVMRPDLVIDIEGYFNHKRTTMTPNNLKQSYL
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHC
PEGAIPINNPVGTAPGILLEKDNYIIISLPGVPREMKIMFEESVLPYIKKKNNLMIISKE
CCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHEEHHHHHHHHCCCCCEEEEEEC
LHFIGIGESTLETKLEDIMDSMNPSLALLAGDGEVKLKITGKGRTKKKIENKISEIVKTV
EEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHH
RNRVGEYIYGEDETSLPDEIGKLLSKRGVTIALAESCTGGLIGARITDIPGSSAYFKGGV
HHHCCCEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEECEEECCCCCCCEECCCE
IAYSNEVKINHLGVNKNTINKEGAVSPETAAEMASGVRQRLEADIGLSVTGIAGPEGGTD
EEEECEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
EKPVGLVYVGLAGIDGEVKTYKLNFKGDRNKNRWLTTQSAFYYLYRYLKFSFK
CCCEEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAEIISIGTELLHGDIVDTNSAYLAEKLTGCGIDVHYISTVGDNKQRLYKTLQQAVERA
CHHHHHHHHHHHHCCCEECCCCHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHC
DLIITTGGLGPTMDDLTREAISEITTCPLVMRPDLVIDIEGYFNHKRTTMTPNNLKQSYL
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHC
PEGAIPINNPVGTAPGILLEKDNYIIISLPGVPREMKIMFEESVLPYIKKKNNLMIISKE
CCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHEEHHHHHHHHCCCCCEEEEEEC
LHFIGIGESTLETKLEDIMDSMNPSLALLAGDGEVKLKITGKGRTKKKIENKISEIVKTV
EEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHH
RNRVGEYIYGEDETSLPDEIGKLLSKRGVTIALAESCTGGLIGARITDIPGSSAYFKGGV
HHHCCCEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEECEEECCCCCCCEECCCE
IAYSNEVKINHLGVNKNTINKEGAVSPETAAEMASGVRQRLEADIGLSVTGIAGPEGGTD
EEEECEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
EKPVGLVYVGLAGIDGEVKTYKLNFKGDRNKNRWLTTQSAFYYLYRYLKFSFK
CCCEEEEEEEEECCCCCEEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA