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The map label for this gene is pepT

Identifier: 220931806

GI number: 220931806

Start: 1041556

End: 1042782

Strand: Reverse

Name: pepT

Synonym: Hore_09630

Alternate gene names: 220931806

Gene position: 1042782-1041556 (Counterclockwise)

Preceding gene: 220931812

Following gene: 220931771

Centisome position: 40.45

GC content: 36.92

Gene sequence:

>1227_bases
ATGGCCAAAGTAGTTGATAGATTTATTAGTTATGTTAAATACAGCACAACATCAAAGGAAGGGTCAGAAACATTCCCCAG
TACTGAAGGACAACTAAAGTTTGCCAGATTACTTGTTGATGAGTTAAAAGAACTGGGATTAAATAATGTTCACCTTGATG
AATATGGATATGTTATGGCTACTGTTCCCTCAAATGTAGACCATAAGGTGCCCACCATCGGGTTTATCGCCCATATGGAC
ACCAGCCCTGATATGAGTGGTACTAATGTTAAACCACAGATTGTAGAAAACTATAATGGAAAAGATATTGTTCTCAATAA
AAGTAAAAATATTATCCTGTCTCCTGATAATTTTCCCGAACTAAAAAAATATACTGGAAAGACTTTAATTACAACAGATG
GGACAACCCTTCTTGGAGCAGACGACAAAGCGGGAATTGCTGAAATAATTACCGCTGTTGAACACCTCATGAATAACCCT
GAATACCCCCATGGTGAAATTAAAATAGCCTTTACCCCTGATGAAGAAATCGGACAGGGTGCAGATAAATTCAGGGTGGA
TAAATTTGGCGCAGATTTTGCCTATACTGTTGACGGCGGTCCTATTGGAGAACTGGAATATGAAAATTTTAATGCAGCCA
GGGCAAAAATAACTGTAAATGGTGTTAATGTTCACCCTGGAACTGCCAAAAATAAAATGAAAAACTCTCTTCTAATAGCA
AATGAATTAATAAATATGCTTCCACCGGCGGAAATACCCGCTCATACCGAGGGCTATGAAGGATTCTTTCATCTAATGTC
TGTAACCGGAAGTGTAGAACAAACCAGGCTTGACTTTATTATCAGAGATTTTTATAAAAACAAATTTGAAGAAAGAAAGA
ATCTAATGGTCAAAATTGCAGATTATTTGAATGTAAAATATGGAGAAAACACAATTACACTGAACCTTAAAGACCAGTAT
TATAATATGAAAGAAAAGATAAAAGAGCATATACATATTGTTTATACAGCACGTCGGGCTATGGAAGAAGTAGGGGTTAC
TCCCAGGGTTAACCCTATCCGTGGTGGTACTGATGGAGCCCGTCTTTCTTATATGGGACTACCAACACCAAACCTCTTTA
CAGGTGGGCACAACTTTCATGGCCGGTATGAATATATCCCTGTATTTGCCATGGAAAAAGCTGTTGATGTAATTTTAAAA
ATTATTGAGTTATATGCAACAAAATAA

Upstream 100 bases:

>100_bases
TTAATATACCCCTTAATAAAAATTATTCTTTATGGTTTATATTACTATTCAAAGCAGGTATAATATATAATATATCATAT
TTGAAAATGGAGGGGTTATT

Downstream 100 bases:

>100_bases
TTTTCCATTGTAACACGTCTCGAGATGGCCCTATGGGAATGGATGACAAACTCCATTAAAAAATACCCCTGCACATGAAG
TGACAGGGGTAAAATAATTT

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAKVVDRFISYVKYSTTSKEGSETFPSTEGQLKFARLLVDELKELGLNNVHLDEYGYVMATVPSNVDHKVPTIGFIAHMD
TSPDMSGTNVKPQIVENYNGKDIVLNKSKNIILSPDNFPELKKYTGKTLITTDGTTLLGADDKAGIAEIITAVEHLMNNP
EYPHGEIKIAFTPDEEIGQGADKFRVDKFGADFAYTVDGGPIGELEYENFNAARAKITVNGVNVHPGTAKNKMKNSLLIA
NELINMLPPAEIPAHTEGYEGFFHLMSVTGSVEQTRLDFIIRDFYKNKFEERKNLMVKIADYLNVKYGENTITLNLKDQY
YNMKEKIKEHIHIVYTARRAMEEVGVTPRVNPIRGGTDGARLSYMGLPTPNLFTGGHNFHGRYEYIPVFAMEKAVDVILK
IIELYATK

Sequences:

>Translated_408_residues
MAKVVDRFISYVKYSTTSKEGSETFPSTEGQLKFARLLVDELKELGLNNVHLDEYGYVMATVPSNVDHKVPTIGFIAHMD
TSPDMSGTNVKPQIVENYNGKDIVLNKSKNIILSPDNFPELKKYTGKTLITTDGTTLLGADDKAGIAEIITAVEHLMNNP
EYPHGEIKIAFTPDEEIGQGADKFRVDKFGADFAYTVDGGPIGELEYENFNAARAKITVNGVNVHPGTAKNKMKNSLLIA
NELINMLPPAEIPAHTEGYEGFFHLMSVTGSVEQTRLDFIIRDFYKNKFEERKNLMVKIADYLNVKYGENTITLNLKDQY
YNMKEKIKEHIHIVYTARRAMEEVGVTPRVNPIRGGTDGARLSYMGLPTPNLFTGGHNFHGRYEYIPVFAMEKAVDVILK
IIELYATK
>Mature_407_residues
AKVVDRFISYVKYSTTSKEGSETFPSTEGQLKFARLLVDELKELGLNNVHLDEYGYVMATVPSNVDHKVPTIGFIAHMDT
SPDMSGTNVKPQIVENYNGKDIVLNKSKNIILSPDNFPELKKYTGKTLITTDGTTLLGADDKAGIAEIITAVEHLMNNPE
YPHGEIKIAFTPDEEIGQGADKFRVDKFGADFAYTVDGGPIGELEYENFNAARAKITVNGVNVHPGTAKNKMKNSLLIAN
ELINMLPPAEIPAHTEGYEGFFHLMSVTGSVEQTRLDFIIRDFYKNKFEERKNLMVKIADYLNVKYGENTITLNLKDQYY
NMKEKIKEHIHIVYTARRAMEEVGVTPRVNPIRGGTDGARLSYMGLPTPNLFTGGHNFHGRYEYIPVFAMEKAVDVILKI
IELYATK

Specific function: Cleaves the N-terminal amino acid of tripeptides

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family

Homologues:

Organism=Escherichia coli, GI1787372, Length=409, Percent_Identity=54.278728606357, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPT_HALOH (B8CWQ0)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508714.1
- ProteinModelPortal:   B8CWQ0
- SMR:   B8CWQ0
- MEROPS:   M20.003
- GeneID:   7313456
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_09630
- HOGENOM:   HBG288638
- OMA:   HMDTAPD
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00550
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161
- PIRSF:   PIRSF037215
- TIGRFAMs:   TIGR01882

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.4.11.4

Molecular weight: Translated: 45688; Mature: 45557

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 80-80 ACT_SITE 175-175

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVVDRFISYVKYSTTSKEGSETFPSTEGQLKFARLLVDELKELGLNNVHLDEYGYVMA
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCEEEE
TVPSNVDHKVPTIGFIAHMDTSPDMSGTNVKPQIVENYNGKDIVLNKSKNIILSPDNFPE
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEECCCCEEECCCCCHH
LKKYTGKTLITTDGTTLLGADDKAGIAEIITAVEHLMNNPEYPHGEIKIAFTPDEEIGQG
HHHHCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHCC
ADKFRVDKFGADFAYTVDGGPIGELEYENFNAARAKITVNGVNVHPGTAKNKMKNSLLIA
CCCEEHHHCCCCEEEEECCCCCCCEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHH
NELINMLPPAEIPAHTEGYEGFFHLMSVTGSVEQTRLDFIIRDFYKNKFEERKNLMVKIA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
DYLNVKYGENTITLNLKDQYYNMKEKIKEHIHIVYTARRAMEEVGVTPRVNPIRGGTDGA
HHHEEEECCEEEEEEECHHHCCHHHHHHHHEEEEHHHHHHHHHCCCCCCCCCCCCCCCCC
RLSYMGLPTPNLFTGGHNFHGRYEYIPVFAMEKAVDVILKIIELYATK
EEEEECCCCCCEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKVVDRFISYVKYSTTSKEGSETFPSTEGQLKFARLLVDELKELGLNNVHLDEYGYVMA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCEEEE
TVPSNVDHKVPTIGFIAHMDTSPDMSGTNVKPQIVENYNGKDIVLNKSKNIILSPDNFPE
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEECCCCEEECCCCCHH
LKKYTGKTLITTDGTTLLGADDKAGIAEIITAVEHLMNNPEYPHGEIKIAFTPDEEIGQG
HHHHCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHCC
ADKFRVDKFGADFAYTVDGGPIGELEYENFNAARAKITVNGVNVHPGTAKNKMKNSLLIA
CCCEEHHHCCCCEEEEECCCCCCCEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHH
NELINMLPPAEIPAHTEGYEGFFHLMSVTGSVEQTRLDFIIRDFYKNKFEERKNLMVKIA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
DYLNVKYGENTITLNLKDQYYNMKEKIKEHIHIVYTARRAMEEVGVTPRVNPIRGGTDGA
HHHEEEECCEEEEEEECHHHCCHHHHHHHHEEEEHHHHHHHHHCCCCCCCCCCCCCCCCC
RLSYMGLPTPNLFTGGHNFHGRYEYIPVFAMEKAVDVILKIIELYATK
EEEEECCCCCCEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA