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The map label for this gene is nrdR

Identifier: 220931762

GI number: 220931762

Start: 992526

End: 992981

Strand: Direct

Name: nrdR

Synonym: Hore_09190

Alternate gene names: 220931762

Gene position: 992526-992981 (Clockwise)

Preceding gene: 220931761

Following gene: 220931763

Centisome position: 38.5

GC content: 35.96

Gene sequence:

>456_bases
ATGAAATGCCCATACTGTCACCATCTGGAAAGTAAAGTAGTTGATTCGAGGTATACTAAAGAACATACTTCAATTCGTCG
TCGGAGAGAATGTCTTAACTGTGGGGAAAGGTTTACAACTTATGAACGTATTGAAGATATACCCCTTATGGTAATTAAAA
GGAATGGACAGCGGGAGTTTTTCGACAGAAATAAATTGTTAACAGGTATAATGAAATCCTGTGAAAAAAGACCTATTCCC
CAGGAGAAGATTGAACAAGTTGTTGATGATATCGAAAAAGAGTTAAATAATAAAATGAAGCAGGAGATAGCCAGTACTGA
AATTGGAGAAATGGTTATGGAACGTTTAAAAGATATTGATGAAGTTGCTTATGTCCGGTTTGCTTCTGTTTACCGCCAGT
TTAAAGACGTAAATAAATTTAAGCAGGAGCTGGAGAGATTACTCCAGGAAGATTAA

Upstream 100 bases:

>100_bases
TGAAGATGTTATACTGGTAAACTTAAATAATGATGGCCAAGTTTAAAAAAAATTGTAGATGTGGTATACTAATGACAGTA
ATCTACGGAGGATGATATTG

Downstream 100 bases:

>100_bases
GGAGGGGGTTTATTCTTTGTTTGTCTGGAATGGAGCCGGGCCCTTACAATACTTAGAAATTGAGGAATTTAAGGACAATG
GGGTTACAGCTATTTTTACA

Product: ATP-cone domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKCPYCHHLESKVVDSRYTKEHTSIRRRRECLNCGERFTTYERIEDIPLMVIKRNGQREFFDRNKLLTGIMKSCEKRPIP
QEKIEQVVDDIEKELNNKMKQEIASTEIGEMVMERLKDIDEVAYVRFASVYRQFKDVNKFKQELERLLQED

Sequences:

>Translated_151_residues
MKCPYCHHLESKVVDSRYTKEHTSIRRRRECLNCGERFTTYERIEDIPLMVIKRNGQREFFDRNKLLTGIMKSCEKRPIP
QEKIEQVVDDIEKELNNKMKQEIASTEIGEMVMERLKDIDEVAYVRFASVYRQFKDVNKFKQELERLLQED
>Mature_151_residues
MKCPYCHHLESKVVDSRYTKEHTSIRRRRECLNCGERFTTYERIEDIPLMVIKRNGQREFFDRNKLLTGIMKSCEKRPIP
QEKIEQVVDDIEKELNNKMKQEIASTEIGEMVMERLKDIDEVAYVRFASVYRQFKDVNKFKQELERLLQED

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=45.578231292517, Blast_Score=147, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_HALOH (B8CWK6)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508670.1
- GeneID:   7313412
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_09190
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18223; Mature: 18223

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPYCHHLESKVVDSRYTKEHTSIRRRRECLNCGERFTTYERIEDIPLMVIKRNGQREF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCHHH
FDRNKLLTGIMKSCEKRPIPQEKIEQVVDDIEKELNNKMKQEIASTEIGEMVMERLKDID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFKDVNKFKQELERLLQED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPYCHHLESKVVDSRYTKEHTSIRRRRECLNCGERFTTYERIEDIPLMVIKRNGQREF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCHHH
FDRNKLLTGIMKSCEKRPIPQEKIEQVVDDIEKELNNKMKQEIASTEIGEMVMERLKDID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFKDVNKFKQELERLLQED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA