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The map label for this gene is murG

Identifier: 220931752

GI number: 220931752

Start: 982387

End: 983502

Strand: Direct

Name: murG

Synonym: Hore_09090

Alternate gene names: 220931752

Gene position: 982387-983502 (Clockwise)

Preceding gene: 220931751

Following gene: 220931753

Centisome position: 38.1

GC content: 38.71

Gene sequence:

>1116_bases
GTGAAATTAGTATTTACTGGAGGGGGGACAGGGGGACATATCTATCCAGCCCTGGCCCTTGCAGAATCGTTTCGCAAAAA
AGGAGATGAAATTCTTTACATTGGTTCTAATGATGGCCTCGAAAGGAGAATAGTACCAGAAGAGGGTTTTGATTTTCAAG
GTATTGAGGTAGCTCCTTTTCCCAGGAATCTCTCTGTTCATCTCTTTTCTTCTTTGTTAAAAACAGGAAGGGGTTTTATT
CAGGCCAGAAAATTATTGAGAAAATTTAAGCCAGATGTTGTAATCGGTACAGGAGGTTTTGTGTCCGGACCTGTAGTACT
GGCTGCTGCTTTACAAAAGATCCCAACAGTAATTCACGAACAGAATGCCTATCCAGGACTGGCAAATAGATTACTGGCTC
CATTTGTTACCCGGATTGCTTTAAATTTCAAAGAGGCGGACAGGCATTTTAAGGAAAAAGCAAGGGAAAAAATAGAGATA
ACCGGAAATCCTATCAGGGAAAGAATATTAACAACTTCCAGGGAGGAAGGACTATTAAATCTGGGTCTTAGAAAAGGCAA
AAAAAATATACTTGTTTTTGGGGGAAGTCAGGGAGCTAAAAATATTAATGAGGCAATGATTGCTTGTTATAGATACTTTA
AAAATAATTCTAAACTACAGATTATTCATTTGACAGGGATGAGAAATTATCAAGAGGTTCTACAGGATTTAAAGGAAAAG
GGATTAGATCCCTCTAAATATACACAATATAAAATAATGCCTTATTTAGATAATATGGAATGGGCTTATGCCGTGGCTGA
CCTGGTTATTTACAGGGCCGGGGCTACTGGTCTGGCTGAGATAACAGCAAAAGGTATCCCTGCAATTTTGATCCCCTACC
CTTATGCAACCGGGAATCATCAAGAACATAATGCCCGTAGCCTTGAAAAAGCGGGGGCGGCAATAGTTATTAAAGATAGC
GAATTAAAGGGTCATAAGTTAGTGAAACTAATAGAAGAATTAATTAATGACGGAAAACGTTTAAAGAAAATGGCTCAATC
CAGTAAAAGGATGGGTAAACCCTGGGCCCGCAATACTTTAATAAATTTAATTGAAGATACTGCAAAGGGTAGTTGA

Upstream 100 bases:

>100_bases
CCTTTATCAGTTATGGAGGCACATCTCTGGTGATTATGTTATCAGGGGTTGGAATTTTATTAAACATATCCCGTCATATT
CTTGAATGAGGTGGAAGAAA

Downstream 100 bases:

>100_bases
AACAGGGGTACATTATAGAGTTAAAAAATGCATATACTGAGATGTGATAGATAAAAGGGGGGAGTATTTTGGCCTCAAAA
AAACATGTTCATCTGATTGG

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKLVFTGGGTGGHIYPALALAESFRKKGDEILYIGSNDGLERRIVPEEGFDFQGIEVAPFPRNLSVHLFSSLLKTGRGFI
QARKLLRKFKPDVVIGTGGFVSGPVVLAAALQKIPTVIHEQNAYPGLANRLLAPFVTRIALNFKEADRHFKEKAREKIEI
TGNPIRERILTTSREEGLLNLGLRKGKKNILVFGGSQGAKNINEAMIACYRYFKNNSKLQIIHLTGMRNYQEVLQDLKEK
GLDPSKYTQYKIMPYLDNMEWAYAVADLVIYRAGATGLAEITAKGIPAILIPYPYATGNHQEHNARSLEKAGAAIVIKDS
ELKGHKLVKLIEELINDGKRLKKMAQSSKRMGKPWARNTLINLIEDTAKGS

Sequences:

>Translated_371_residues
MKLVFTGGGTGGHIYPALALAESFRKKGDEILYIGSNDGLERRIVPEEGFDFQGIEVAPFPRNLSVHLFSSLLKTGRGFI
QARKLLRKFKPDVVIGTGGFVSGPVVLAAALQKIPTVIHEQNAYPGLANRLLAPFVTRIALNFKEADRHFKEKAREKIEI
TGNPIRERILTTSREEGLLNLGLRKGKKNILVFGGSQGAKNINEAMIACYRYFKNNSKLQIIHLTGMRNYQEVLQDLKEK
GLDPSKYTQYKIMPYLDNMEWAYAVADLVIYRAGATGLAEITAKGIPAILIPYPYATGNHQEHNARSLEKAGAAIVIKDS
ELKGHKLVKLIEELINDGKRLKKMAQSSKRMGKPWARNTLINLIEDTAKGS
>Mature_371_residues
MKLVFTGGGTGGHIYPALALAESFRKKGDEILYIGSNDGLERRIVPEEGFDFQGIEVAPFPRNLSVHLFSSLLKTGRGFI
QARKLLRKFKPDVVIGTGGFVSGPVVLAAALQKIPTVIHEQNAYPGLANRLLAPFVTRIALNFKEADRHFKEKAREKIEI
TGNPIRERILTTSREEGLLNLGLRKGKKNILVFGGSQGAKNINEAMIACYRYFKNNSKLQIIHLTGMRNYQEVLQDLKEK
GLDPSKYTQYKIMPYLDNMEWAYAVADLVIYRAGATGLAEITAKGIPAILIPYPYATGNHQEHNARSLEKAGAAIVIKDS
ELKGHKLVKLIEELINDGKRLKKMAQSSKRMGKPWARNTLINLIEDTAKGS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=370, Percent_Identity=33.2432432432432, Blast_Score=191, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_HALOH (B8CWJ6)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508660.1
- ProteinModelPortal:   B8CWJ6
- SMR:   B8CWJ6
- GeneID:   7313402
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_09090
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41212; Mature: 41212

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVFTGGGTGGHIYPALALAESFRKKGDEILYIGSNDGLERRIVPEEGFDFQGIEVAPF
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCCCEEECCC
PRNLSVHLFSSLLKTGRGFIQARKLLRKFKPDVVIGTGGFVSGPVVLAAALQKIPTVIHE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHC
QNAYPGLANRLLAPFVTRIALNFKEADRHFKEKAREKIEITGNPIRERILTTSREEGLLN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCHHCCHHH
LGLRKGKKNILVFGGSQGAKNINEAMIACYRYFKNNSKLQIIHLTGMRNYQEVLQDLKEK
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHC
GLDPSKYTQYKIMPYLDNMEWAYAVADLVIYRAGATGLAEITAKGIPAILIPYPYATGNH
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCC
QEHNARSLEKAGAAIVIKDSELKGHKLVKLIEELINDGKRLKKMAQSSKRMGKPWARNTL
CCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHH
INLIEDTAKGS
HHHHHHHCCCC
>Mature Secondary Structure
MKLVFTGGGTGGHIYPALALAESFRKKGDEILYIGSNDGLERRIVPEEGFDFQGIEVAPF
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCCCEEECCC
PRNLSVHLFSSLLKTGRGFIQARKLLRKFKPDVVIGTGGFVSGPVVLAAALQKIPTVIHE
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHC
QNAYPGLANRLLAPFVTRIALNFKEADRHFKEKAREKIEITGNPIRERILTTSREEGLLN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCHHCCHHH
LGLRKGKKNILVFGGSQGAKNINEAMIACYRYFKNNSKLQIIHLTGMRNYQEVLQDLKEK
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHC
GLDPSKYTQYKIMPYLDNMEWAYAVADLVIYRAGATGLAEITAKGIPAILIPYPYATGNH
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCC
QEHNARSLEKAGAAIVIKDSELKGHKLVKLIEELINDGKRLKKMAQSSKRMGKPWARNTL
CCCHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHH
INLIEDTAKGS
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA