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The map label for this gene is frr

Identifier: 220931612

GI number: 220931612

Start: 825293

End: 825850

Strand: Direct

Name: frr

Synonym: Hore_07680

Alternate gene names: 220931612

Gene position: 825293-825850 (Clockwise)

Preceding gene: 220931611

Following gene: 220931613

Centisome position: 32.01

GC content: 36.38

Gene sequence:

>558_bases
ATGATTAAACAGGTAGAGAAAAATGCCAAACAAAAAATGGAGAAGGTTTTAGAAGCTACAAAGCATGATTTAAATACGGT
TAGAACCGGCCGGGCCAGGCCATCCCTGGTAGAAAATATTATGGTTGATTATTACGGAACCCAGACACCCATTCAGCAGA
TGGCTAAAGTAGTAGCTCCTGAAGCAAGACAGCTCGTTATTGAACCCTGGGATAAGAGTGTTATAGAAAGTATTGAAAAA
GCTATTTTAAAATCAAACCTGGGTTTAAACCCTTCAAATGATGGTAATGTCATCAGGATTAATATTCCCCAGTTGACTGA
AGAGAGAAGGAAAGAACTGGTTAAGGTAGCCCATGAAAAGGCAGAAAAAGGTAGAATTGCTATAAGAAATATTAGACGTG
AAGCCAATGATGAATTAAAGGAAATGGAAAAAAACAGTGAAATATCTGAAGATAACTACCACCGGGGACTTGATATGATT
CAGGAACTAACTGATACATATATAGATAAAATAGATAAAATGCTTGAAGATAAAGAACAGGATATTATGGAGGTTTAG

Upstream 100 bases:

>100_bases
TAATATTCTAAATTATTATGACTTCTTTAATTTATTCAGGCTTAATATTTATATATAAATTAAGAGAAACCTCTAAAATA
ATACTAATGGGGGGAAGATT

Downstream 100 bases:

>100_bases
AATGGATAATTATTTAATCGGGTCCAGTCCTGATTCTGTAAAAAAACATTATGAGAAAAAAGGGAAACGGGTAATCGTAA
ACCAGACTAAACCTCCTGAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIKQVEKNAKQKMEKVLEATKHDLNTVRTGRARPSLVENIMVDYYGTQTPIQQMAKVVAPEARQLVIEPWDKSVIESIEK
AILKSNLGLNPSNDGNVIRINIPQLTEERRKELVKVAHEKAEKGRIAIRNIRREANDELKEMEKNSEISEDNYHRGLDMI
QELTDTYIDKIDKMLEDKEQDIMEV

Sequences:

>Translated_185_residues
MIKQVEKNAKQKMEKVLEATKHDLNTVRTGRARPSLVENIMVDYYGTQTPIQQMAKVVAPEARQLVIEPWDKSVIESIEK
AILKSNLGLNPSNDGNVIRINIPQLTEERRKELVKVAHEKAEKGRIAIRNIRREANDELKEMEKNSEISEDNYHRGLDMI
QELTDTYIDKIDKMLEDKEQDIMEV
>Mature_185_residues
MIKQVEKNAKQKMEKVLEATKHDLNTVRTGRARPSLVENIMVDYYGTQTPIQQMAKVVAPEARQLVIEPWDKSVIESIEK
AILKSNLGLNPSNDGNVIRINIPQLTEERRKELVKVAHEKAEKGRIAIRNIRREANDELKEMEKNSEISEDNYHRGLDMI
QELTDTYIDKIDKMLEDKEQDIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=175, Percent_Identity=26.2857142857143, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=47.5675675675676, Blast_Score=186, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=24.8554913294798, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_HALOH (B8CW56)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508520.1
- ProteinModelPortal:   B8CW56
- SMR:   B8CW56
- GeneID:   7314755
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_07680
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   CLSK2806294
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21423; Mature: 21423

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQVEKNAKQKMEKVLEATKHDLNTVRTGRARPSLVENIMVDYYGTQTPIQQMAKVVAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCC
EARQLVIEPWDKSVIESIEKAILKSNLGLNPSNDGNVIRINIPQLTEERRKELVKVAHEK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEKGRIAIRNIRREANDELKEMEKNSEISEDNYHRGLDMIQELTDTYIDKIDKMLEDKEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIMEV
HHHCC
>Mature Secondary Structure
MIKQVEKNAKQKMEKVLEATKHDLNTVRTGRARPSLVENIMVDYYGTQTPIQQMAKVVAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCC
EARQLVIEPWDKSVIESIEKAILKSNLGLNPSNDGNVIRINIPQLTEERRKELVKVAHEK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEKGRIAIRNIRREANDELKEMEKNSEISEDNYHRGLDMIQELTDTYIDKIDKMLEDKEQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA