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The map label for this gene is spoIIAB [H]

Identifier: 220931545

GI number: 220931545

Start: 760796

End: 761227

Strand: Direct

Name: spoIIAB [H]

Synonym: Hore_07010

Alternate gene names: 220931545

Gene position: 760796-761227 (Clockwise)

Preceding gene: 220931544

Following gene: 220931546

Centisome position: 29.51

GC content: 36.11

Gene sequence:

>432_bases
TTGCGTAATCAGGCCCATTTAAAACTATTAAGCAAAAGCAGTAATGTTGGACTGGCCCGGGTAGCGGTAGCTACCTTTGC
TTCGGAATTGGATTTTACTCTAAATGAACTCGAAGAAATTAAAGTAGCTGTATCTGAAGCAGTAACAAACTGTATAATTC
ATGGTTATCCGATGAAAGAAGGGACAATAGATATTGAAATGGAAATAACAGGTGATAAATTAACGGTTATAGTTACTGAT
TATGGGGTTGGTATTGAAGATGTAGAGGCGGTTTTACGTCCTTCATTTACAACAAAAGATGAACATATGGGACTGGGACT
GGCTTTTATTGATTCCTTTATGGATGATTTTAAACTGGAATCAGAGTTGAATAAAGGAACCAGAGTTATAATGGTAAAAG
TTCCGGAACGTTATAAGCAGGTAAAGAAATAA

Upstream 100 bases:

>100_bases
GAGAAAATATTTGAACTTTCCGGTATGTTAAAGATTATGTCTGTTTTCAATAACGAGGAAGACGCCCTGGCCGGGTTAAA
TAGTAAAGGAGGTAATCATA

Downstream 100 bases:

>100_bases
GGAGAGGAATAAAATGGAATACAGTATTATCAACCTTCCCAAAGTAAGGTTGTTAAGTGAGGAGGAGACCAGGCATTACA
TTAAGAAGGCCCAGAATAAT

Product: putative anti-sigma regulatory factor, serine/threonine protein kinase

Products: NA

Alternate protein names: Stage II sporulation protein AB [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MRNQAHLKLLSKSSNVGLARVAVATFASELDFTLNELEEIKVAVSEAVTNCIIHGYPMKEGTIDIEMEITGDKLTVIVTD
YGVGIEDVEAVLRPSFTTKDEHMGLGLAFIDSFMDDFKLESELNKGTRVIMVKVPERYKQVKK

Sequences:

>Translated_143_residues
MRNQAHLKLLSKSSNVGLARVAVATFASELDFTLNELEEIKVAVSEAVTNCIIHGYPMKEGTIDIEMEITGDKLTVIVTD
YGVGIEDVEAVLRPSFTTKDEHMGLGLAFIDSFMDDFKLESELNKGTRVIMVKVPERYKQVKK
>Mature_143_residues
MRNQAHLKLLSKSSNVGLARVAVATFASELDFTLNELEEIKVAVSEAVTNCIIHGYPMKEGTIDIEMEITGDKLTVIVTD
YGVGIEDVEAVLRPSFTTKDEHMGLGLAFIDSFMDDFKLESELNKGTRVIMVKVPERYKQVKK

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010194
- InterPro:   IPR003594 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 15924; Mature: 15924

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNQAHLKLLSKSSNVGLARVAVATFASELDFTLNELEEIKVAVSEAVTNCIIHGYPMKE
CCCHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTIDIEMEITGDKLTVIVTDYGVGIEDVEAVLRPSFTTKDEHMGLGLAFIDSFMDDFKLE
CEEEEEEEEECCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SELNKGTRVIMVKVPERYKQVKK
HHCCCCCEEEEEECCHHHHHHCC
>Mature Secondary Structure
MRNQAHLKLLSKSSNVGLARVAVATFASELDFTLNELEEIKVAVSEAVTNCIIHGYPMKE
CCCHHHEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTIDIEMEITGDKLTVIVTDYGVGIEDVEAVLRPSFTTKDEHMGLGLAFIDSFMDDFKLE
CEEEEEEEEECCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SELNKGTRVIMVKVPERYKQVKK
HHCCCCCEEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA