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The map label for this gene is xseA

Identifier: 220931493

GI number: 220931493

Start: 703919

End: 705136

Strand: Direct

Name: xseA

Synonym: Hore_06490

Alternate gene names: 220931493

Gene position: 703919-705136 (Clockwise)

Preceding gene: 220931492

Following gene: 220931494

Centisome position: 27.3

GC content: 39.98

Gene sequence:

>1218_bases
ATGGAGTCTAAAATATACACTGTATCTGAAGTTACCGGTCGAATAACAGAATTATTAACTTCGGATTCTGTTTTAAATGA
CCTCTGGATAACCGGGGAAATATCAAATTTCCATCATCACAACTCCGGACATATGTATTTTACAATAAAGGATGAAAGGT
CCTGTATTAAATCAATTATGTTCAGGGGGTATAACCGTAAGCTTAAATTTGAGCCAGAAGACGGGTTGAAGGTTAACGCC
CATGGCTATGTCGGTGTCTACAAACCCCGTGGTGATTACCAGTTTTATGTAGACCATCTCGAGCCTGCCGGAAAAGGAGC
CCTTTACCTTGCTTTTGAGCAGTTAAAGGAAAAACTTGAAAAAGAAGGTTTATTTAACGAAGATCATAAAAAAGAAATTC
CCCTGTTGCCGCGAAAAATAGGGGTTGTTACTTCGCCAACCGGGGCAGCTATCAGGGATATATTATCAGTGGTTAAACGG
AGATTTAAAAATGTTTCGGTTTTAATAGTGCCTTCTCTGGTTCAGGGTAAAAAGGCAGCCAGGGAAATTGTTGAGGGAAT
AGAATACCTTAATTCACGGGATGATATTGATGTTATTATTGTAAGCCGTGGTGGTGGGTCTATTGAGGAACTCTGGTCTT
TTAATGAAGAAGTTGTTGCCAGGGCTATATATAATTCCAGGATTCCGGTAATAAGTGGAGTCGGACATGAAACAGATTTT
ACTATAGCCGATTTTGTGGCTGATCTCAGAGCACCTACTCCATCTGCTGCTGCAGAGCTGGCTATATCTAACCGGATTGA
ACTGGAAAAACACCTTGTCAATCTTTATACCAGATTATATAATTCGGTCAGTTATCAAATAAAAAGTTACCGGGATAGAT
TGAATTCACTCTCTTTAAAAAAAGTTCTGACCAGGCCAGAAGAATTATTTATTCAAAAAATACAATATGTTGATGAATTA
TCAAGACGGCTGGATTGGGCCATGGAAGGCCGGTTGAAAGATGCCCGTGAAAAATTCAGGGTTTTAAGTGGTAAGCTGGA
TAGTCTCAGCCCCCTGAAGACTATTGAGAGGGGATATAGTATAACCCTGAAGGGGAGTGAACCCATTAATAGTATCACTC
AGGTTGATATAGGTGATGTAATCAGGAGTCGCCTTAGTGATGGAATTATATTGAGTCAGGTAAAGAGGACCATGAAAGAA
GGTGAACAGGATGGCTGA

Upstream 100 bases:

>100_bases
GCCCGCCAGAGGGCTGGTTACATAACTCCGGTGCCCGGAGGAGTAGGTCCGATGACCATAGCCATGCTTATGAAAAATAC
TGTTAAAGCCAGGAAGTATC

Downstream 100 bases:

>100_bases
AGAAAGTAAGGAAAAAGAGTTGAATTTTGAAAAGGCCCTGAAAAGGCTTGAAGAGATAGTAGATTGTCTGGAGACAGGTG
GTTTAAGCCTTGATAAATCA

Product: exodeoxyribonuclease VII, large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MESKIYTVSEVTGRITELLTSDSVLNDLWITGEISNFHHHNSGHMYFTIKDERSCIKSIMFRGYNRKLKFEPEDGLKVNA
HGYVGVYKPRGDYQFYVDHLEPAGKGALYLAFEQLKEKLEKEGLFNEDHKKEIPLLPRKIGVVTSPTGAAIRDILSVVKR
RFKNVSVLIVPSLVQGKKAAREIVEGIEYLNSRDDIDVIIVSRGGGSIEELWSFNEEVVARAIYNSRIPVISGVGHETDF
TIADFVADLRAPTPSAAAELAISNRIELEKHLVNLYTRLYNSVSYQIKSYRDRLNSLSLKKVLTRPEELFIQKIQYVDEL
SRRLDWAMEGRLKDAREKFRVLSGKLDSLSPLKTIERGYSITLKGSEPINSITQVDIGDVIRSRLSDGIILSQVKRTMKE
GEQDG

Sequences:

>Translated_405_residues
MESKIYTVSEVTGRITELLTSDSVLNDLWITGEISNFHHHNSGHMYFTIKDERSCIKSIMFRGYNRKLKFEPEDGLKVNA
HGYVGVYKPRGDYQFYVDHLEPAGKGALYLAFEQLKEKLEKEGLFNEDHKKEIPLLPRKIGVVTSPTGAAIRDILSVVKR
RFKNVSVLIVPSLVQGKKAAREIVEGIEYLNSRDDIDVIIVSRGGGSIEELWSFNEEVVARAIYNSRIPVISGVGHETDF
TIADFVADLRAPTPSAAAELAISNRIELEKHLVNLYTRLYNSVSYQIKSYRDRLNSLSLKKVLTRPEELFIQKIQYVDEL
SRRLDWAMEGRLKDAREKFRVLSGKLDSLSPLKTIERGYSITLKGSEPINSITQVDIGDVIRSRLSDGIILSQVKRTMKE
GEQDG
>Mature_405_residues
MESKIYTVSEVTGRITELLTSDSVLNDLWITGEISNFHHHNSGHMYFTIKDERSCIKSIMFRGYNRKLKFEPEDGLKVNA
HGYVGVYKPRGDYQFYVDHLEPAGKGALYLAFEQLKEKLEKEGLFNEDHKKEIPLLPRKIGVVTSPTGAAIRDILSVVKR
RFKNVSVLIVPSLVQGKKAAREIVEGIEYLNSRDDIDVIIVSRGGGSIEELWSFNEEVVARAIYNSRIPVISGVGHETDF
TIADFVADLRAPTPSAAAELAISNRIELEKHLVNLYTRLYNSVSYQIKSYRDRLNSLSLKKVLTRPEELFIQKIQYVDEL
SRRLDWAMEGRLKDAREKFRVLSGKLDSLSPLKTIERGYSITLKGSEPINSITQVDIGDVIRSRLSDGIILSQVKRTMKE
GEQDG

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=437, Percent_Identity=40.045766590389, Blast_Score=327, Evalue=8e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_HALOH (B8D2H9)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508401.1
- GeneID:   7314555
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_06490
- HOGENOM:   HBG634411
- OMA:   PWPVRTV
- ProtClustDB:   CLSK2806257
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 45908; Mature: 45908

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKIYTVSEVTGRITELLTSDSVLNDLWITGEISNFHHHNSGHMYFTIKDERSCIKSIM
CCCCEEEHHHHHHHHHHHHHCCHHHHHEEEEEECCCCEECCCCEEEEEECCHHHHHHHHH
FRGYNRKLKFEPEDGLKVNAHGYVGVYKPRGDYQFYVDHLEPAGKGALYLAFEQLKEKLE
HCCCCCCEEECCCCCCEEECCEEEEEECCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHH
KEGLFNEDHKKEIPLLPRKIGVVTSPTGAAIRDILSVVKRRFKNVSVLIVPSLVQGKKAA
HCCCCCCCCCCCCCCCCHHCCEEECCCHHHHHHHHHHHHHHHCCCEEEEECCHHCCHHHH
REIVEGIEYLNSRDDIDVIIVSRGGGSIEELWSFNEEVVARAIYNSRIPVISGVGHETDF
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCC
TIADFVADLRAPTPSAAAELAISNRIELEKHLVNLYTRLYNSVSYQIKSYRDRLNSLSLK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVLTRPEELFIQKIQYVDELSRRLDWAMEGRLKDAREKFRVLSGKLDSLSPLKTIERGYS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCE
ITLKGSEPINSITQVDIGDVIRSRLSDGIILSQVKRTMKEGEQDG
EEECCCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MESKIYTVSEVTGRITELLTSDSVLNDLWITGEISNFHHHNSGHMYFTIKDERSCIKSIM
CCCCEEEHHHHHHHHHHHHHCCHHHHHEEEEEECCCCEECCCCEEEEEECCHHHHHHHHH
FRGYNRKLKFEPEDGLKVNAHGYVGVYKPRGDYQFYVDHLEPAGKGALYLAFEQLKEKLE
HCCCCCCEEECCCCCCEEECCEEEEEECCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHH
KEGLFNEDHKKEIPLLPRKIGVVTSPTGAAIRDILSVVKRRFKNVSVLIVPSLVQGKKAA
HCCCCCCCCCCCCCCCCHHCCEEECCCHHHHHHHHHHHHHHHCCCEEEEECCHHCCHHHH
REIVEGIEYLNSRDDIDVIIVSRGGGSIEELWSFNEEVVARAIYNSRIPVISGVGHETDF
HHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCC
TIADFVADLRAPTPSAAAELAISNRIELEKHLVNLYTRLYNSVSYQIKSYRDRLNSLSLK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVLTRPEELFIQKIQYVDELSRRLDWAMEGRLKDAREKFRVLSGKLDSLSPLKTIERGYS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCE
ITLKGSEPINSITQVDIGDVIRSRLSDGIILSQVKRTMKEGEQDG
EEECCCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA