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The map label for this gene is aroQ

Identifier: 220931457

GI number: 220931457

Start: 667610

End: 668056

Strand: Direct

Name: aroQ

Synonym: Hore_06130

Alternate gene names: 220931457

Gene position: 667610-668056 (Clockwise)

Preceding gene: 220931456

Following gene: 220931458

Centisome position: 25.89

GC content: 40.94

Gene sequence:

>447_bases
GTGAATAGGGTAGCTGTTATTCATGGTCCAAACCTGAACTTACTTGGCAGGCGGGAGCCGGAAGTATATGGGACAAAAAG
CCTGGAAAATATCAATAAAGAAATTGAGAAAAGGGCTAATAACCTGAAAATTGAGGTTGACATTTTCCAGAGTAACCATG
AAGGGGAAATAATTGATTTTATTCATGACAATTATAAAGCCCTTAGTGGTATCATTATTAACCCCGGTGGGTTGACCCAT
TACAGTATTGCTCTGAGGGATGCCCTGGCAGCCGTACGTCTTCCTGTAGTTGAGGTACATATCAGTAATATTCATAAAAG
AGAAGACTTCAGGCACAGGTCTGTTATTGCTTCAGTTGCGGTCGGTCAGATTACCGGACTGGGGACAGAGGGTTATTTAT
ATGCCCTGGAAGCCATTGTTAATATTATTAAAAAGGGGAGTTATTAA

Upstream 100 bases:

>100_bases
ATAATAAATTGACCTGGATTTTACTCAAAAATATAGGTAAAGGCTTTATTAAAAATGATGTAAATGATAATATAATTAAT
GAGGTACTGGAGGGGTTAAA

Downstream 100 bases:

>100_bases
AATGGAAAAGAGAATACAGCAATTAAGAAAAGCTATGAAAAAAATGGATCTGGACAGTTTGATTATTGATTCCAGCCATA
ACCGATTTTATTTAACCGGT

Product: 3-dehydroquinate dehydratase, type II

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MNRVAVIHGPNLNLLGRREPEVYGTKSLENINKEIEKRANNLKIEVDIFQSNHEGEIIDFIHDNYKALSGIIINPGGLTH
YSIALRDALAAVRLPVVEVHISNIHKREDFRHRSVIASVAVGQITGLGTEGYLYALEAIVNIIKKGSY

Sequences:

>Translated_148_residues
MNRVAVIHGPNLNLLGRREPEVYGTKSLENINKEIEKRANNLKIEVDIFQSNHEGEIIDFIHDNYKALSGIIINPGGLTH
YSIALRDALAAVRLPVVEVHISNIHKREDFRHRSVIASVAVGQITGLGTEGYLYALEAIVNIIKKGSY
>Mature_148_residues
MNRVAVIHGPNLNLLGRREPEVYGTKSLENINKEIEKRANNLKIEVDIFQSNHEGEIIDFIHDNYKALSGIIINPGGLTH
YSIALRDALAAVRLPVVEVHISNIHKREDFRHRSVIASVAVGQITGLGTEGYLYALEAIVNIIKKGSY

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_HALOH (B8D2E3)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002508365.1
- ProteinModelPortal:   B8D2E3
- SMR:   B8D2E3
- GeneID:   7314518
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_06130
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16478; Mature: 16478

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 100-100 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVAVIHGPNLNLLGRREPEVYGTKSLENINKEIEKRANNLKIEVDIFQSNHEGEIIDF
CCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCEEEE
IHDNYKALSGIIINPGGLTHYSIALRDALAAVRLPVVEVHISNIHKREDFRHRSVIASVA
HHCCHHHHCCEEECCCCCEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
VGQITGLGTEGYLYALEAIVNIIKKGSY
HHHEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNRVAVIHGPNLNLLGRREPEVYGTKSLENINKEIEKRANNLKIEVDIFQSNHEGEIIDF
CCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCEEEE
IHDNYKALSGIIINPGGLTHYSIALRDALAAVRLPVVEVHISNIHKREDFRHRSVIASVA
HHCCHHHHCCEEECCCCCEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
VGQITGLGTEGYLYALEAIVNIIKKGSY
HHHEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA