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The map label for this gene is aroB [H]

Identifier: 220931456

GI number: 220931456

Start: 666516

End: 667613

Strand: Direct

Name: aroB [H]

Synonym: Hore_06120

Alternate gene names: 220931456

Gene position: 666516-667613 (Clockwise)

Preceding gene: 220931455

Following gene: 220931457

Centisome position: 25.85

GC content: 39.89

Gene sequence:

>1098_bases
TTGGACTTTAAATCAATTGAAGTCAATATACCTTCAAAGACAGTAAATTATTCTATAATTATTGGACAAGGACTGATGGA
GAATGCTGGTTCCTTAATTAAGGATGTTTACCGGGGAAGGAAAATTATGGTGGTAACTGATGAAAATGTGGATGGGTTAT
ATGGTGACATCATGTTAAAGTCACTGGAAAAAGAAGGGTTTGTTGTTATCAAATATATAATTCCGCCTGGGGAAAAGTCA
AAGAGCAATTATTATCTTCATAAGGGTTATGATATCATGGTTGAAAATGGATTTGGAAGGGATCATCTGGTAGTAGCCTT
CGGTGGAGGCGTAGTCGGTGATCTGGCCGGTTATCTGGCTGCAACATACATGAGGGGGATTGGCCTGGTACAGATACCGA
CTACACTGCTGTCCCAGGTTGATAGCAGTGTTGGTGGAAAGACAGCGATAAACCATCCAGCCGGTAAAAACCTGATCGGT
GCTTTTTATCAACCGGACAGGGTTATTATAGATGTCGGGGTCCTGAAATCACTGGAAAAGAGGGAATTGCGGGCCGGGAT
GGCCGAGGTTATAAAATATGGTTTGATATTCGACAGTGATTTTGTAGATTACCTCCGGAATAATTATCAGGAGGTATTTG
TTTATAATCCCCGTGTTCTGGGGAGGATAATTGAACAGTCATGTAATTATAAAGCCAGGATAGTGGAAGAAGATCAAAAA
GAAAAGGGTATCAGGGCCCTGTTGAATTTTGGTCATACTATTGGCCATTCCCTGGAGGCTGTAACCGGGTATAGAAAGTA
TAAACATGGTGAAGCTGTGGCCATTGGAATGGTGGGGGCAGCCCGGTTGTCAGAAAGGTTGGAGTTGCTTCAGGAAGGTG
AGGCAGATAAGGTTGCAGAAATTTTAAGATTATATGGATTACCCCTTTCCTATCAGTATGGTGAAGACCCTGAGATGGTT
TATAAAACCCTTTTTTATGATAAAAAAGTAAAAGATAATAAATTGACCTGGATTTTACTCAAAAATATAGGTAAAGGCTT
TATTAAAAATGATGTAAATGATAATATAATTAATGAGGTACTGGAGGGGTTAAAGTGA

Upstream 100 bases:

>100_bases
GAACAATATTATAGTCAGTTTGATAATCAGGTTTATACGGGAGGCAAGGAGAAGAGAGAAGTTGTAGATGAAATTATTCA
CCTGATAGGAGTTGATAGGC

Downstream 100 bases:

>100_bases
ATAGGGTAGCTGTTATTCATGGTCCAAACCTGAACTTACTTGGCAGGCGGGAGCCGGAAGTATATGGGACAAAAAGCCTG
GAAAATATCAATAAAGAAAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MDFKSIEVNIPSKTVNYSIIIGQGLMENAGSLIKDVYRGRKIMVVTDENVDGLYGDIMLKSLEKEGFVVIKYIIPPGEKS
KSNYYLHKGYDIMVENGFGRDHLVVAFGGGVVGDLAGYLAATYMRGIGLVQIPTTLLSQVDSSVGGKTAINHPAGKNLIG
AFYQPDRVIIDVGVLKSLEKRELRAGMAEVIKYGLIFDSDFVDYLRNNYQEVFVYNPRVLGRIIEQSCNYKARIVEEDQK
EKGIRALLNFGHTIGHSLEAVTGYRKYKHGEAVAIGMVGAARLSERLELLQEGEADKVAEILRLYGLPLSYQYGEDPEMV
YKTLFYDKKVKDNKLTWILLKNIGKGFIKNDVNDNIINEVLEGLK

Sequences:

>Translated_365_residues
MDFKSIEVNIPSKTVNYSIIIGQGLMENAGSLIKDVYRGRKIMVVTDENVDGLYGDIMLKSLEKEGFVVIKYIIPPGEKS
KSNYYLHKGYDIMVENGFGRDHLVVAFGGGVVGDLAGYLAATYMRGIGLVQIPTTLLSQVDSSVGGKTAINHPAGKNLIG
AFYQPDRVIIDVGVLKSLEKRELRAGMAEVIKYGLIFDSDFVDYLRNNYQEVFVYNPRVLGRIIEQSCNYKARIVEEDQK
EKGIRALLNFGHTIGHSLEAVTGYRKYKHGEAVAIGMVGAARLSERLELLQEGEADKVAEILRLYGLPLSYQYGEDPEMV
YKTLFYDKKVKDNKLTWILLKNIGKGFIKNDVNDNIINEVLEGLK
>Mature_365_residues
MDFKSIEVNIPSKTVNYSIIIGQGLMENAGSLIKDVYRGRKIMVVTDENVDGLYGDIMLKSLEKEGFVVIKYIIPPGEKS
KSNYYLHKGYDIMVENGFGRDHLVVAFGGGVVGDLAGYLAATYMRGIGLVQIPTTLLSQVDSSVGGKTAINHPAGKNLIG
AFYQPDRVIIDVGVLKSLEKRELRAGMAEVIKYGLIFDSDFVDYLRNNYQEVFVYNPRVLGRIIEQSCNYKARIVEEDQK
EKGIRALLNFGHTIGHSLEAVTGYRKYKHGEAVAIGMVGAARLSERLELLQEGEADKVAEILRLYGLPLSYQYGEDPEMV
YKTLFYDKKVKDNKLTWILLKNIGKGFIKNDVNDNIINEVLEGLK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=342, Percent_Identity=43.5672514619883, Blast_Score=273, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6320332, Length=326, Percent_Identity=37.1165644171779, Blast_Score=208, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40780; Mature: 40780

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKSIEVNIPSKTVNYSIIIGQGLMENAGSLIKDVYRGRKIMVVTDENVDGLYGDIMLK
CCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
SLEKEGFVVIKYIIPPGEKSKSNYYLHKGYDIMVENGFGRDHLVVAFGGGVVGDLAGYLA
HHCCCCEEEEEEEECCCCCCCCCEEEECCEEEEEECCCCCCEEEEEECCCHHHHHHHHHH
ATYMRGIGLVQIPTTLLSQVDSSVGGKTAINHPAGKNLIGAFYQPDRVIIDVGVLKSLEK
HHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEEHHHHHHHHH
RELRAGMAEVIKYGLIFDSDFVDYLRNNYQEVFVYNPRVLGRIIEQSCNYKARIVEEDQK
HHHHHHHHHHHHHHCEECHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCCEEEEECCHHH
EKGIRALLNFGHTIGHSLEAVTGYRKYKHGEAVAIGMVGAARLSERLELLQEGEADKVAE
HHHHHHHHHHCHHHHCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHH
ILRLYGLPLSYQYGEDPEMVYKTLFYDKKVKDNKLTWILLKNIGKGFIKNDVNDNIINEV
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCHHHCCCCCHHHHHHH
LEGLK
HHHCC
>Mature Secondary Structure
MDFKSIEVNIPSKTVNYSIIIGQGLMENAGSLIKDVYRGRKIMVVTDENVDGLYGDIMLK
CCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
SLEKEGFVVIKYIIPPGEKSKSNYYLHKGYDIMVENGFGRDHLVVAFGGGVVGDLAGYLA
HHCCCCEEEEEEEECCCCCCCCCEEEECCEEEEEECCCCCCEEEEEECCCHHHHHHHHHH
ATYMRGIGLVQIPTTLLSQVDSSVGGKTAINHPAGKNLIGAFYQPDRVIIDVGVLKSLEK
HHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEEHHHHHHHHH
RELRAGMAEVIKYGLIFDSDFVDYLRNNYQEVFVYNPRVLGRIIEQSCNYKARIVEEDQK
HHHHHHHHHHHHHHCEECHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCCEEEEECCHHH
EKGIRALLNFGHTIGHSLEAVTGYRKYKHGEAVAIGMVGAARLSERLELLQEGEADKVAE
HHHHHHHHHHCHHHHCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHH
ILRLYGLPLSYQYGEDPEMVYKTLFYDKKVKDNKLTWILLKNIGKGFIKNDVNDNIINEV
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCHHHCCCCCHHHHHHH
LEGLK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA