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The map label for this gene is kdsC [H]

Identifier: 220931355

GI number: 220931355

Start: 556532

End: 557035

Strand: Direct

Name: kdsC [H]

Synonym: Hore_05100

Alternate gene names: 220931355

Gene position: 556532-557035 (Clockwise)

Preceding gene: 220931353

Following gene: 220931358

Centisome position: 21.59

GC content: 40.87

Gene sequence:

>504_bases
ATGGATAAAACTATTGTAGAAAAGGCTGCCCGGATTAATTTGATAATCACAGATGTTGATGGAGTTTTAACCGATGGGAG
GATTGTTCTCGGTAACAATGGTGAAGAATTTAAATTTTTTCATGTTCAGGATGGACAGGGTATAAAAAGGGCCCAGAAGG
CCGGGCTTAAAGTTGCCATTATTACCGGAAGGATATCTAAAGCTGTAGACAGGCGGGCCAAGGAGCTTAACATCGGTGAG
GTTTATCAGGGAGTAAATGATAAATTAATTATTTATAAAAAGCTGTGTAACAAATATAACTTAAAGAATGAAGAGGTTGC
TTACATAGGCGATGATATTGCGGACCTGGATGTCTTAAAAGAAGTCGGTTTTGCCTGTTCAGTGAAAAATGGGGTCAGTG
CAGTAAAAGAAATGGTAGATTATGTTACTGACAGGGAAGGGGGCCGCGGGGCTGTCCGTGAAGTTATTGACCTTATCCTG
GAAGCCAGATCAAATCCTGTCTGA

Upstream 100 bases:

>100_bases
TGGTGTCACCTCCTAAAAATAGTAGAAAATATATTTAAAATAATATTTTATAATAGTATACTGTTAATAGGTGTTATTTG
TTCAAAGGGAGGGATACAAT

Downstream 100 bases:

>100_bases
GTTTTATAACTGGTTTCAGGATGGTCGTTTAAAGATGGCTATGGATTAAGACGGCCACGGGCTGTATTACAGTAATCAGG
TGAGATATCAATCCCCAGAT

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MDKTIVEKAARINLIITDVDGVLTDGRIVLGNNGEEFKFFHVQDGQGIKRAQKAGLKVAIITGRISKAVDRRAKELNIGE
VYQGVNDKLIIYKKLCNKYNLKNEEVAYIGDDIADLDVLKEVGFACSVKNGVSAVKEMVDYVTDREGGRGAVREVIDLIL
EARSNPV

Sequences:

>Translated_167_residues
MDKTIVEKAARINLIITDVDGVLTDGRIVLGNNGEEFKFFHVQDGQGIKRAQKAGLKVAIITGRISKAVDRRAKELNIGE
VYQGVNDKLIIYKKLCNKYNLKNEEVAYIGDDIADLDVLKEVGFACSVKNGVSAVKEMVDYVTDREGGRGAVREVIDLIL
EARSNPV
>Mature_167_residues
MDKTIVEKAARINLIITDVDGVLTDGRIVLGNNGEEFKFFHVQDGQGIKRAQKAGLKVAIITGRISKAVDRRAKELNIGE
VYQGVNDKLIIYKKLCNKYNLKNEEVAYIGDDIADLDVLKEVGFACSVKNGVSAVKEMVDYVTDREGGRGAVREVIDLIL
EARSNPV

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=30.718954248366, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI2367202, Length=159, Percent_Identity=48.4276729559748, Blast_Score=145, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18394; Mature: 18394

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTIVEKAARINLIITDVDGVLTDGRIVLGNNGEEFKFFHVQDGQGIKRAQKAGLKVAI
CCHHHHHHHHHEEEEEECCCCEEECCEEEECCCCCEEEEEEEECCCCHHHHHHCCCEEEE
ITGRISKAVDRRAKELNIGEVYQGVNDKLIIYKKLCNKYNLKNEEVAYIGDDIADLDVLK
EECHHHHHHHHHHHHCCHHHHHCCCCCCEEHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
EVGFACSVKNGVSAVKEMVDYVTDREGGRGAVREVIDLILEARSNPV
HCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKTIVEKAARINLIITDVDGVLTDGRIVLGNNGEEFKFFHVQDGQGIKRAQKAGLKVAI
CCHHHHHHHHHEEEEEECCCCEEECCEEEECCCCCEEEEEEEECCCCHHHHHHCCCEEEE
ITGRISKAVDRRAKELNIGEVYQGVNDKLIIYKKLCNKYNLKNEEVAYIGDDIADLDVLK
EECHHHHHHHHHHHHCCHHHHHCCCCCCEEHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
EVGFACSVKNGVSAVKEMVDYVTDREGGRGAVREVIDLILEARSNPV
HCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]