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The map label for this gene is mucK [H]

Identifier: 220931326

GI number: 220931326

Start: 516663

End: 517934

Strand: Direct

Name: mucK [H]

Synonym: Hore_04810

Alternate gene names: 220931326

Gene position: 516663-517934 (Clockwise)

Preceding gene: 220931325

Following gene: 220931327

Centisome position: 20.04

GC content: 42.61

Gene sequence:

>1272_bases
ATGTCTGTCTTCTTGTTTGTGGATCAGAATGCTATGAACCCGATAATTAACGATTTGGTGGCTGAATATGGGGTTGGTGA
AGATAAAATTGGGATTATCGGGTCAGCCTTCATTATACTGGGGGCAGTTGTAAGCCTTATTTTTGGTTATCTGGCTGATA
AAAAGAGCCGGAAGATGTTACTGGCCTTTGTTGTCCTTGTCGGGGAAATACCATGTTTTTTAACCGGTTTTGAGTATTTC
ACCCGGACTTATGAACAGTTATTAATATTAAGAATATTGACTGGATTGGGAATAGGAGGTATCTTTCCCCTGACCTTTTC
CCTGATCGGGGATTATTTCCCCGCTGGACAGCGTGGCATAATAAATGCTATGGTAACAACAGCCTGGGGAGTAGGTCAGA
TCCTGGGACAGACCCTGGCTGGTTTTTTATCAGGTCCCTATGGCTGGAGATTACCTTTTATTATAGCAGCTGTCCCCAAT
TTTGTCCTCGTTCCTTTGTTTGTTTTGGTGGCCCGGGAACCGAAACGTGGGGCCCAGGAAGAAGAATTATCAGAAGTAAT
AGAACAGGGTCTGGAGTACAGGGAAAAGATAAAGTTTTCGGATTTGAAAGAAATATTTAAAAATAAGACAAATATATTGG
GTTTCCTGCAGGGGATTCCTGGTTCCCTTCCCTGGGGGTTAATCCCCTTCTTCATAGTTCCCTTTTATGAACTACATAAG
GGTTTTTCCCGTGGTATGGCCACCATTTTGAGTCTCTTCCTGGGGATAGGAGCTACCGTAGGAGGTATCTTTGGTGGCTG
GATGGGTGATAAAATTTATAAAAAATCTCCCAGGATGCTACCGGTTTTTAATGCTGTTTTCATATTACTCGGGGTAATCC
CAGGATTTTTTCTCATGGGACTCAATTATGGCTCTGACCCCGGGTGGAATGAGTTAATACTTCCACTTATTTTCAGTTTC
TGTACCGGGGTTGTAGTTTCTTTGCCGGCCCCCAATATTAAATCTATTTTGATTAATGTAAACCCTCCAGAACACCGGGG
TACTGTTTTTTCGATACATAATCTGACCGATAGTCTGGGACGTGGTGTTGGTCCCCTTATCGGTGGGTTTCTGGTTGTAT
CCCAGGGTTATCAATGGACTATGTATTTTGCTGTTTTTGCCTGGATTCCCTGTGGCCTTATATATTTATGGATGTACCGT
ACTATAGATAATGATCTGGATACACTCAGGGGTTATCTGAAAAGAAAACGGGAGAAAATTATCGGGATGTAA

Upstream 100 bases:

>100_bases
TTTAATTCTTTAAGGAAATAAAACATTAAAGGGGGTATACAAAATAGGAGTTACAAAATTATCTACCAGAGATAAGTGGA
CTTTGGTGTTATTGGTGTTG

Downstream 100 bases:

>100_bases
GAATGTCAGGGACTAACTAAATTGAGTAGTTAAAAGTATCTGATTTAGTAAGAAACTTCCTGCAACTATAATTGTTTAAA
AGGTAAATGCCAATATCATC

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSVFLFVDQNAMNPIINDLVAEYGVGEDKIGIIGSAFIILGAVVSLIFGYLADKKSRKMLLAFVVLVGEIPCFLTGFEYF
TRTYEQLLILRILTGLGIGGIFPLTFSLIGDYFPAGQRGIINAMVTTAWGVGQILGQTLAGFLSGPYGWRLPFIIAAVPN
FVLVPLFVLVAREPKRGAQEEELSEVIEQGLEYREKIKFSDLKEIFKNKTNILGFLQGIPGSLPWGLIPFFIVPFYELHK
GFSRGMATILSLFLGIGATVGGIFGGWMGDKIYKKSPRMLPVFNAVFILLGVIPGFFLMGLNYGSDPGWNELILPLIFSF
CTGVVVSLPAPNIKSILINVNPPEHRGTVFSIHNLTDSLGRGVGPLIGGFLVVSQGYQWTMYFAVFAWIPCGLIYLWMYR
TIDNDLDTLRGYLKRKREKIIGM

Sequences:

>Translated_423_residues
MSVFLFVDQNAMNPIINDLVAEYGVGEDKIGIIGSAFIILGAVVSLIFGYLADKKSRKMLLAFVVLVGEIPCFLTGFEYF
TRTYEQLLILRILTGLGIGGIFPLTFSLIGDYFPAGQRGIINAMVTTAWGVGQILGQTLAGFLSGPYGWRLPFIIAAVPN
FVLVPLFVLVAREPKRGAQEEELSEVIEQGLEYREKIKFSDLKEIFKNKTNILGFLQGIPGSLPWGLIPFFIVPFYELHK
GFSRGMATILSLFLGIGATVGGIFGGWMGDKIYKKSPRMLPVFNAVFILLGVIPGFFLMGLNYGSDPGWNELILPLIFSF
CTGVVVSLPAPNIKSILINVNPPEHRGTVFSIHNLTDSLGRGVGPLIGGFLVVSQGYQWTMYFAVFAWIPCGLIYLWMYR
TIDNDLDTLRGYLKRKREKIIGM
>Mature_422_residues
SVFLFVDQNAMNPIINDLVAEYGVGEDKIGIIGSAFIILGAVVSLIFGYLADKKSRKMLLAFVVLVGEIPCFLTGFEYFT
RTYEQLLILRILTGLGIGGIFPLTFSLIGDYFPAGQRGIINAMVTTAWGVGQILGQTLAGFLSGPYGWRLPFIIAAVPNF
VLVPLFVLVAREPKRGAQEEELSEVIEQGLEYREKIKFSDLKEIFKNKTNILGFLQGIPGSLPWGLIPFFIVPFYELHKG
FSRGMATILSLFLGIGATVGGIFGGWMGDKIYKKSPRMLPVFNAVFILLGVIPGFFLMGLNYGSDPGWNELILPLIFSFC
TGVVVSLPAPNIKSILINVNPPEHRGTVFSIHNLTDSLGRGVGPLIGGFLVVSQGYQWTMYFAVFAWIPCGLIYLWMYRT
IDNDLDTLRGYLKRKREKIIGM

Specific function: Probable uptake of muconate [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789515, Length=391, Percent_Identity=23.0179028132992, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082320, Length=393, Percent_Identity=22.9007633587786, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46770; Mature: 46639

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
SVFLFVDQNAMNPIINDLVAEYGVGEDKIGIIGSAFIILGAVVSLIFGYLADKKSRKML
EEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LAFVVLVGEIPCFLTGFEYFTRTYEQLLILRILTGLGIGGIFPLTFSLIGDYFPAGQRGI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHH
INAMVTTAWGVGQILGQTLAGFLSGPYGWRLPFIIAAVPNFVLVPLFVLVAREPKRGAQE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EELSEVIEQGLEYREKIKFSDLKEIFKNKTNILGFLQGIPGSLPWGLIPFFIVPFYELHK
HHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GFSRGMATILSLFLGIGATVGGIFGGWMGDKIYKKSPRMLPVFNAVFILLGVIPGFFLMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
LNYGSDPGWNELILPLIFSFCTGVVVSLPAPNIKSILINVNPPEHRGTVFSIHNLTDSLG
CCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCEEEEEECCCCCCCCCEEEHHHHHHHHC
RGVGPLIGGFLVVSQGYQWTMYFAVFAWIPCGLIYLWMYRTIDNDLDTLRGYLKRKREKI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IGM
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]