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The map label for this gene is bglA [H]

Identifier: 220931327

GI number: 220931327

Start: 518050

End: 519348

Strand: Direct

Name: bglA [H]

Synonym: Hore_04820

Alternate gene names: 220931327

Gene position: 518050-519348 (Clockwise)

Preceding gene: 220931326

Following gene: 220931329

Centisome position: 20.09

GC content: 41.72

Gene sequence:

>1299_bases
ATGTCATTAAAACTACCACAGGATTTACTGCTCGGGGCAGCAACTTCAGCCCTGCAGATTGAAGGAGGAGATAAAAATAA
TAACTGGTATCAGTGGTGTGAAGAGGGACACATTAAAGATGGGAGTCATTGCCTTAATGCCAACGATCACTGGAATAGAT
ACCGCGAAGATATTGAACTTATAAAAAAACTGGGTCTTGAAACCTATAGAATGGGGCTGGAGTGGAGTCGAATAGAGCAT
CAGCCCGGTAAATTTAGTAAGGAAGGAATCGAACATTACCGTGATGAAATTACCCTTCTCCTTGAAAATGGGGTTGTTCC
CCTGGTGACCCTTCATCATTTTTCTCACCCCCTGTGGCTTGTTAATAAAGGGGGCTGGGGGAATAAAAAGGTAGTTGATT
ATTTTAAGCGGTATACAGAGTATGTAGTCGAAAATCTGGGGGATCTGGTGAGTGACTGGATTACCATTAATGAACCCAAT
GTCTTTCTCTATAATGGATATGTTGAAGGTATCTGGCCTCCGGGAAAAAACAATATTTTTTCTATGTTCAGGGCCATGAA
GAATATGATAAAAGCCCATATAGTCTCCTATAAGACTATTCATCAGGTCAGGTCTAAACATAATTTTGAGGGAGAAACAA
GGGTTGGAGTTGCCAACCATGTCAGACTGTTTGACCCGGCTGGAAATAAAAAAATACATGGAATACCGGCCCGCCTCCTT
GATTACTTTTTTCACCGCCTGGTTATGGAAGGAATGGCCAGGGGAAAGTTTATGTTTCCCATCGGTACCGGGGGACACCC
CCTGGGGGAGGGGAGGTATTATGACTTTATCGGGATTAATTATTATACCAGGGATATTATTAAGTTTACCCTGAATCCGG
CCTCCCTGTTTGCCAGGATGGAAGTTAAGGAAGGAGCAGATACCAGTGACCTCGGCTGGGAAATATATCCTGTGGGCCTG
AAGAGGGTCTGTCGTAAATATTATGAGGAATATCAGGCCCCTGTATTTATTACCGAAAACGGTATTTGTGATAAGGGGGA
TACCAAAAGAGGGCACTTTATCTATGACCATTTAAAAGAAGTAGTAAAGCTGATTAATGAAGGTATTCCCGTTGAGAGGT
ATTATTACTGGACTTTGATAGATAACTTTGAATGGATTGAAGGTGAAAGTGCCCGGTTTGGCCTGATCCATAATGATTTT
AAAACTCAGAAACGATCCATCAGGATCAGTGGTTATTTTTATGGGAAAATATGCAAGACAAAAGAGATTACCCCCGAAAT
GGAGAGAATTTATCTTTAA

Upstream 100 bases:

>100_bases
ACTAAATTGAGTAGTTAAAAGTATCTGATTTAGTAAGAAACTTCCTGCAACTATAATTGTTTAAAAGGTAAATGCCAATA
TCATCTGAAGGGGGTTAATT

Downstream 100 bases:

>100_bases
TTATCAATATCCAGATTCTGGTCTACCTCACTCCCTGTCAAAGGGGGTTTTTTCTTTATTACCTTTTTCTGCCATTTGCC
AGTTAGATACATTATAAAAC

Product: Beta-glucosidase

Products: NA

Alternate protein names: Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSLKLPQDLLLGAATSALQIEGGDKNNNWYQWCEEGHIKDGSHCLNANDHWNRYREDIELIKKLGLETYRMGLEWSRIEH
QPGKFSKEGIEHYRDEITLLLENGVVPLVTLHHFSHPLWLVNKGGWGNKKVVDYFKRYTEYVVENLGDLVSDWITINEPN
VFLYNGYVEGIWPPGKNNIFSMFRAMKNMIKAHIVSYKTIHQVRSKHNFEGETRVGVANHVRLFDPAGNKKIHGIPARLL
DYFFHRLVMEGMARGKFMFPIGTGGHPLGEGRYYDFIGINYYTRDIIKFTLNPASLFARMEVKEGADTSDLGWEIYPVGL
KRVCRKYYEEYQAPVFITENGICDKGDTKRGHFIYDHLKEVVKLINEGIPVERYYYWTLIDNFEWIEGESARFGLIHNDF
KTQKRSIRISGYFYGKICKTKEITPEMERIYL

Sequences:

>Translated_432_residues
MSLKLPQDLLLGAATSALQIEGGDKNNNWYQWCEEGHIKDGSHCLNANDHWNRYREDIELIKKLGLETYRMGLEWSRIEH
QPGKFSKEGIEHYRDEITLLLENGVVPLVTLHHFSHPLWLVNKGGWGNKKVVDYFKRYTEYVVENLGDLVSDWITINEPN
VFLYNGYVEGIWPPGKNNIFSMFRAMKNMIKAHIVSYKTIHQVRSKHNFEGETRVGVANHVRLFDPAGNKKIHGIPARLL
DYFFHRLVMEGMARGKFMFPIGTGGHPLGEGRYYDFIGINYYTRDIIKFTLNPASLFARMEVKEGADTSDLGWEIYPVGL
KRVCRKYYEEYQAPVFITENGICDKGDTKRGHFIYDHLKEVVKLINEGIPVERYYYWTLIDNFEWIEGESARFGLIHNDF
KTQKRSIRISGYFYGKICKTKEITPEMERIYL
>Mature_431_residues
SLKLPQDLLLGAATSALQIEGGDKNNNWYQWCEEGHIKDGSHCLNANDHWNRYREDIELIKKLGLETYRMGLEWSRIEHQ
PGKFSKEGIEHYRDEITLLLENGVVPLVTLHHFSHPLWLVNKGGWGNKKVVDYFKRYTEYVVENLGDLVSDWITINEPNV
FLYNGYVEGIWPPGKNNIFSMFRAMKNMIKAHIVSYKTIHQVRSKHNFEGETRVGVANHVRLFDPAGNKKIHGIPARLLD
YFFHRLVMEGMARGKFMFPIGTGGHPLGEGRYYDFIGINYYTRDIIKFTLNPASLFARMEVKEGADTSDLGWEIYPVGLK
RVCRKYYEEYQAPVFITENGICDKGDTKRGHFIYDHLKEVVKLINEGIPVERYYYWTLIDNFEWIEGESARFGLIHNDFK
TQKRSIRISGYFYGKICKTKEITPEMERIYL

Specific function: Can Hydrolyze Salicin, Cellobiose, And Probably Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=448, Percent_Identity=28.7946428571429, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI32481206, Length=466, Percent_Identity=27.2532188841202, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI110681710, Length=474, Percent_Identity=27.2151898734177, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI28376633, Length=461, Percent_Identity=25.5965292841649, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI24497614, Length=398, Percent_Identity=25.6281407035176, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=26.2939958592132, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI2367174, Length=453, Percent_Identity=27.5938189845475, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI2367270, Length=489, Percent_Identity=24.9488752556237, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17552856, Length=473, Percent_Identity=30.4439746300211, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17539390, Length=470, Percent_Identity=31.2765957446809, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI21356577, Length=475, Percent_Identity=28, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 50445; Mature: 50314

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKLPQDLLLGAATSALQIEGGDKNNNWYQWCEEGHIKDGSHCLNANDHWNRYREDIEL
CCCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHH
IKKLGLETYRMGLEWSRIEHQPGKFSKEGIEHYRDEITLLLENGVVPLVTLHHFSHPLWL
HHHHCCHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCEEEEEEECCCCCEEE
VNKGGWGNKKVVDYFKRYTEYVVENLGDLVSDWITINEPNVFLYNGYVEGIWPPGKNNIF
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEECCEEEEECCCCCCHHH
SMFRAMKNMIKAHIVSYKTIHQVRSKHNFEGETRVGVANHVRLFDPAGNKKIHGIPARLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCEECCCHHHHH
DYFFHRLVMEGMARGKFMFPIGTGGHPLGEGRYYDFIGINYYTRDIIKFTLNPASLFARM
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCHHEEEEEHEECCHHHHHEEE
EVKEGADTSDLGWEIYPVGLKRVCRKYYEEYQAPVFITENGICDKGDTKRGHFIYDHLKE
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHH
VVKLINEGIPVERYYYWTLIDNFEWIEGESARFGLIHNDFKTQKRSIRISGYFYGKICKT
HHHHHHCCCCCCEEEEEEEECCEEEECCCCCEEEEEECCCCCCCCEEEEEEEEEEEEECC
KEITPEMERIYL
CCCCCHHHHHCC
>Mature Secondary Structure 
SLKLPQDLLLGAATSALQIEGGDKNNNWYQWCEEGHIKDGSHCLNANDHWNRYREDIEL
CCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHH
IKKLGLETYRMGLEWSRIEHQPGKFSKEGIEHYRDEITLLLENGVVPLVTLHHFSHPLWL
HHHHCCHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHEEEEECCCCEEEEEEECCCCCEEE
VNKGGWGNKKVVDYFKRYTEYVVENLGDLVSDWITINEPNVFLYNGYVEGIWPPGKNNIF
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEECCEEEEECCCCCCHHH
SMFRAMKNMIKAHIVSYKTIHQVRSKHNFEGETRVGVANHVRLFDPAGNKKIHGIPARLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCEECCCHHHHH
DYFFHRLVMEGMARGKFMFPIGTGGHPLGEGRYYDFIGINYYTRDIIKFTLNPASLFARM
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCHHEEEEEHEECCHHHHHEEE
EVKEGADTSDLGWEIYPVGLKRVCRKYYEEYQAPVFITENGICDKGDTKRGHFIYDHLKE
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHH
VVKLINEGIPVERYYYWTLIDNFEWIEGESARFGLIHNDFKTQKRSIRISGYFYGKICKT
HHHHHHCCCCCCEEEEEEEECCEEEECCCCCEEEEEECCCCCCCCEEEEEEEEEEEEECC
KEITPEMERIYL
CCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8277941 [H]