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The map label for this gene is ycbL [H]

Identifier: 220931316

GI number: 220931316

Start: 505224

End: 505937

Strand: Direct

Name: ycbL [H]

Synonym: Hore_04710

Alternate gene names: 220931316

Gene position: 505224-505937 (Clockwise)

Preceding gene: 220931315

Following gene: 220931317

Centisome position: 19.6

GC content: 42.02

Gene sequence:

>714_bases
ATGGCTGATGGGAGTAGAATACTGGTAGTTGATGATGAACAGGAAATAAGGGAATTACTAAAAAGTTATCTGGAGAGGGA
AGGTTATGTTGTCGATACTGTTAAAGATGGGAAAACAGCCCTTTTCCGTGTATCAAACCAGGACTATAACCTGGTTATTC
TGGATATAATGCTACCCGATACAGATGGGGTTGAGGTTTGTCGCACTATCAGGGAGATAACCAATATTCCCATTATTATG
CTTACTGCCCGGGATAGTGAAGTAGATAAAGTACTGGGATTGAGGATAGGAGCCGATGATTATATTACAAAACCCTTTCT
ACCCGGTGAACTGATAGCCCGGGTTAAAGCTCAGTTGCGACGATTTTTTGTTCTCGGTAGTGAGGGTGATGCCCGGTCCC
GGAAGATGGTTAAGTTTGGTGACCTGAAGATAGATTTTGATGGATACCGGGTTTATAAAAGGAATAAAGAGGTACAGTTG
ACCTCAACTGAATTTAAAATACTTTTACTCCTGGCCCGGGAACCCGGGAAGGTTTTTACCAAGAAGCAGATTTTTAATAA
GGTGTGGGGGGATGATTACCTGGAGGCCGATAACAACGTCATGGTACATATAAGAAGATTGAGAACTAAAATAGAAGATG
ATCCCAAAAATCCTGAATTTATCGAGACTGTCTGGGGGATTGGTTACAGGTTTGCCGGTGATGAAAATGACTGA

Upstream 100 bases:

>100_bases
TCCAGGAAATTATAAAGGATAATTTATTTATATGGTAAAACTATATATTAAGTATTATTATATAAAAAATATTTAAAAAG
TTAAAATGGAGTGAGAACAG

Downstream 100 bases:

>100_bases
GAAACGGTTTCTGGCCATGACAGGGTTGGTATTGATCCTGGCTTTATTCTTGCTGGATTCAAACCATGTCACGAGACAGA
TAATACTCATATTAACCGTG

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MADGSRILVVDDEQEIRELLKSYLEREGYVVDTVKDGKTALFRVSNQDYNLVILDIMLPDTDGVEVCRTIREITNIPIIM
LTARDSEVDKVLGLRIGADDYITKPFLPGELIARVKAQLRRFFVLGSEGDARSRKMVKFGDLKIDFDGYRVYKRNKEVQL
TSTEFKILLLLAREPGKVFTKKQIFNKVWGDDYLEADNNVMVHIRRLRTKIEDDPKNPEFIETVWGIGYRFAGDEND

Sequences:

>Translated_237_residues
MADGSRILVVDDEQEIRELLKSYLEREGYVVDTVKDGKTALFRVSNQDYNLVILDIMLPDTDGVEVCRTIREITNIPIIM
LTARDSEVDKVLGLRIGADDYITKPFLPGELIARVKAQLRRFFVLGSEGDARSRKMVKFGDLKIDFDGYRVYKRNKEVQL
TSTEFKILLLLAREPGKVFTKKQIFNKVWGDDYLEADNNVMVHIRRLRTKIEDDPKNPEFIETVWGIGYRFAGDEND
>Mature_236_residues
ADGSRILVVDDEQEIRELLKSYLEREGYVVDTVKDGKTALFRVSNQDYNLVILDIMLPDTDGVEVCRTIREITNIPIIML
TARDSEVDKVLGLRIGADDYITKPFLPGELIARVKAQLRRFFVLGSEGDARSRKMVKFGDLKIDFDGYRVYKRNKEVQLT
STEFKILLLLAREPGKVFTKKQIFNKVWGDDYLEADNNVMVHIRRLRTKIEDDPKNPEFIETVWGIGYRFAGDEND

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=37.8723404255319, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=38.3259911894273, Blast_Score=173, Evalue=9e-45,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=39.2241379310345, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=40.3508771929825, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=41.4529914529915, Blast_Score=166, Evalue=9e-43,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.8260869565217, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=37.3333333333333, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=34.2105263157895, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=36.0515021459227, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=36.2445414847162, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=32.618025751073, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=34.6491228070175, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.3030303030303, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.4786324786325, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=116, Percent_Identity=32.7586206896552, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=101, Percent_Identity=40.5940594059406, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=34.6534653465347, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27357; Mature: 27226

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGSRILVVDDEQEIRELLKSYLEREGYVVDTVKDGKTALFRVSNQDYNLVILDIMLPD
CCCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEEEEEECC
TDGVEVCRTIREITNIPIIMLTARDSEVDKVLGLRIGADDYITKPFLPGELIARVKAQLR
CCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHH
RFFVLGSEGDARSRKMVKFGDLKIDFDGYRVYKRNKEVQLTSTEFKILLLLAREPGKVFT
HEEEECCCCCCCCCEEEEECCEEEECCCEEEEECCCEEEEECCCEEEEEEEECCCCCHHH
KKQIFNKVWGDDYLEADNNVMVHIRRLRTKIEDDPKNPEFIETVWGIGYRFAGDEND
HHHHHHHHCCCCCEECCCCEEEEEEHHHHHHCCCCCCCHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
ADGSRILVVDDEQEIRELLKSYLEREGYVVDTVKDGKTALFRVSNQDYNLVILDIMLPD
CCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEEEEEECC
TDGVEVCRTIREITNIPIIMLTARDSEVDKVLGLRIGADDYITKPFLPGELIARVKAQLR
CCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHH
RFFVLGSEGDARSRKMVKFGDLKIDFDGYRVYKRNKEVQLTSTEFKILLLLAREPGKVFT
HEEEECCCCCCCCCEEEEECCEEEECCCEEEEECCCEEEEECCCEEEEEEEECCCCCHHH
KKQIFNKVWGDDYLEADNNVMVHIRRLRTKIEDDPKNPEFIETVWGIGYRFAGDEND
HHHHHHHHCCCCCEECCCCEEEEEEHHHHHHCCCCCCCHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]