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The map label for this gene is citE [H]

Identifier: 220931313

GI number: 220931313

Start: 501074

End: 501958

Strand: Direct

Name: citE [H]

Synonym: Hore_04680

Alternate gene names: 220931313

Gene position: 501074-501958 (Clockwise)

Preceding gene: 220931312

Following gene: 220931314

Centisome position: 19.44

GC content: 39.55

Gene sequence:

>885_bases
TTGAAAAATAAATTAAGAAGAAGTATGCTCTATATTCCGGCCAATAATCCAGGTATGATCCAGGATGCTTTCATTTATGG
TGCAGATGCTATATTGTTTGATCTTGAGGACTCTATTACTCTGACAGAAAAGGATGCTGCCCGTTATCTCCTCTGTAATG
CCCTTCAAGAACTGGATTTTGGTCAGGCAGAGATTGTGGTCAGAATTAACCCCCTTAATACAGAATATGGCAGGAATGAT
TTAGAAGTAATAGTACCGGCAAAACCTGATGCTATCAGGGTACCAAAGGTTGAAACAGGTGAGCAAATAAAAAAGATAGA
TAGTTTATTAGGGAAATTAGAAAGAAAAGCCGGGATAACTCGGGGTAGTATAGAAATTATGGCTATGATAGAGACAGCAC
GGGGTGTTTTAAATGCCCGGGAAATTGCCAAGGCTTCTCCAAGAATTACTGCGTTGAACCTGGGAGCGGAAGACCTGACT
GCAGATCTGGGTGTCAGGAGAAGTGATGAGGGAATTGAATTATTATATGCACGTTCTCAGATTATTTATGCAGCTGCAGA
GAACGGAATTGATATTATTGATACCGTATATAGTGATGTTGAGAATATTACTGGTTTAAAAGAGGAAGCTATCATGAGTA
AAAGACTGGGGTTTACAGGCAAATCTGTAATTCACCCCAAACAAATAGAAATTGTTAATAGTGTATTTACCCCTTCCACA
GAGGAAATAAAGGAAGCAGAAAAAATTGTAAAACGGGCACTTGAAGCAGAAAAAAGGGGGTTTGGTGTGGTGACTGTTGA
TGGAAAAATGGTTGATATACCTGTTATAGAGCGGGCTAAAAAGCTGCTTGACCGGGTAGAATCAATAAGGAGGGCTAGTA
ATTGA

Upstream 100 bases:

>100_bases
AATGTGTATATTCGTGCTCAGGATAGAGGAGCACTGGATTATGCAATAAAGGCAAGAACCAGGACAGCCCTGGAGAGGGC
CAGCAAGGGGGCTGAAGAGA

Downstream 100 bases:

>100_bases
GGGAGAATACAATTCCTGAAAGGGTAGGTTCATTTAAAAATCTTCGTTCCTATAGTTATATAAAGCCAGAAAGGAAAAGT
AAAATTATTGGTAGTTTAGA

Product: Citrate (pro-3S)-lyase subunit beta

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKNKLRRSMLYIPANNPGMIQDAFIYGADAILFDLEDSITLTEKDAARYLLCNALQELDFGQAEIVVRINPLNTEYGRND
LEVIVPAKPDAIRVPKVETGEQIKKIDSLLGKLERKAGITRGSIEIMAMIETARGVLNAREIAKASPRITALNLGAEDLT
ADLGVRRSDEGIELLYARSQIIYAAAENGIDIIDTVYSDVENITGLKEEAIMSKRLGFTGKSVIHPKQIEIVNSVFTPST
EEIKEAEKIVKRALEAEKRGFGVVTVDGKMVDIPVIERAKKLLDRVESIRRASN

Sequences:

>Translated_294_residues
MKNKLRRSMLYIPANNPGMIQDAFIYGADAILFDLEDSITLTEKDAARYLLCNALQELDFGQAEIVVRINPLNTEYGRND
LEVIVPAKPDAIRVPKVETGEQIKKIDSLLGKLERKAGITRGSIEIMAMIETARGVLNAREIAKASPRITALNLGAEDLT
ADLGVRRSDEGIELLYARSQIIYAAAENGIDIIDTVYSDVENITGLKEEAIMSKRLGFTGKSVIHPKQIEIVNSVFTPST
EEIKEAEKIVKRALEAEKRGFGVVTVDGKMVDIPVIERAKKLLDRVESIRRASN
>Mature_294_residues
MKNKLRRSMLYIPANNPGMIQDAFIYGADAILFDLEDSITLTEKDAARYLLCNALQELDFGQAEIVVRINPLNTEYGRND
LEVIVPAKPDAIRVPKVETGEQIKKIDSLLGKLERKAGITRGSIEIMAMIETARGVLNAREIAKASPRITALNLGAEDLT
ADLGVRRSDEGIELLYARSQIIYAAAENGIDIIDTVYSDVENITGLKEEAIMSKRLGFTGKSVIHPKQIEIVNSVFTPST
EEIKEAEKIVKRALEAEKRGFGVVTVDGKMVDIPVIERAKKLLDRVESIRRASN

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=295, Percent_Identity=31.864406779661, Blast_Score=165, Evalue=5e-41,
Organism=Escherichia coli, GI87081764, Length=286, Percent_Identity=44.4055944055944, Blast_Score=247, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17557458, Length=299, Percent_Identity=29.4314381270903, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 32523; Mature: 32523

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLRRSMLYIPANNPGMIQDAFIYGADAILFDLEDSITLTEKDAARYLLCNALQELDF
CCCCCCCCEEEEECCCCCCEEHHHEECCCEEEEECCCCEEEEHHHHHHHHHHHHHHHCCC
GQAEIVVRINPLNTEYGRNDLEVIVPAKPDAIRVPKVETGEQIKKIDSLLGKLERKAGIT
CCEEEEEEEECCCCCCCCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCC
RGSIEIMAMIETARGVLNAREIAKASPRITALNLGAEDLTADLGVRRSDEGIELLYARSQ
CCCHHEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCEEEEEECCE
IIYAAAENGIDIIDTVYSDVENITGLKEEAIMSKRLGFTGKSVIHPKQIEIVNSVFTPST
EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCH
EEIKEAEKIVKRALEAEKRGFGVVTVDGKMVDIPVIERAKKLLDRVESIRRASN
HHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNKLRRSMLYIPANNPGMIQDAFIYGADAILFDLEDSITLTEKDAARYLLCNALQELDF
CCCCCCCCEEEEECCCCCCEEHHHEECCCEEEEECCCCEEEEHHHHHHHHHHHHHHHCCC
GQAEIVVRINPLNTEYGRNDLEVIVPAKPDAIRVPKVETGEQIKKIDSLLGKLERKAGIT
CCEEEEEEEECCCCCCCCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCC
RGSIEIMAMIETARGVLNAREIAKASPRITALNLGAEDLTADLGVRRSDEGIELLYARSQ
CCCHHEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCEEEEEECCE
IIYAAAENGIDIIDTVYSDVENITGLKEEAIMSKRLGFTGKSVIHPKQIEIVNSVFTPST
EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCH
EEIKEAEKIVKRALEAEKRGFGVVTVDGKMVDIPVIERAKKLLDRVESIRRASN
HHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]