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The map label for this gene is citC [H]

Identifier: 220931311

GI number: 220931311

Start: 499731

End: 500810

Strand: Direct

Name: citC [H]

Synonym: Hore_04660

Alternate gene names: 220931311

Gene position: 499731-500810 (Clockwise)

Preceding gene: 220931310

Following gene: 220931312

Centisome position: 19.38

GC content: 36.85

Gene sequence:

>1080_bases
GTGTCAATATGGAACCTGCGAAAGGAAATTCTTTATCCACCTGTAGATGATATGACAGAAGTGGCAACATTTCTTAATGG
ACTCAATCTTGAACTGGAAGAAAGGCTTGATTGTATTCTCGTCCTTAGAATAAATAACAGGGTTGTTGGTACCGGGGGCC
TGGATGGGAACATTTTGAAATGTGTGGGGGTGGACCCTGAGTTTCAGAATCAGGGTCTTTTAAATACTATTGTAAGTGAG
TTGAAACATATATTGTACAGAAAAGGGTATAATAGTCTTTTTGTTTATACCCCGGAACACCAGGTTGTAAGATATAAGAA
TCTCGGGTTTGTTGAAATTGAATCAGTTGGGGATTATCCCGTTTTAATGGAAGATAGTATGGAGGGGTTTAATGGTTTTA
TACGTAGTTTAAAGAAAAAAACACAGAGAATTAATTTAGATTTAAAAAAAATAGAAGTGGCATCCCTTGTTATGAACTGT
AATCCCTTTACTAAAGGACACCTCTATTTGATTGAAAAAGCAGCCAGGGAACGTGATATTGTTTTTATCTTTTTGTTGAC
AGAAGATCGTTCCCTTTTTCCTGCTAACATTAGATATGAACTGGTAAAAAAGGGTACTAAACACCTTGATAATGTTATTG
TTTTCAGGGGAGGGGATTATATATTATCTTATACTACTTTTCCTGATTATTTTATAGGTTCCCAGAGAGGTGAAGAAAAA
GCCAGGCGGTATGCAGAACTTGATGCCAGAATATTTGCCCGACATATTGCCCCTGCCCTTAACATTAACCACCGTTATGT
GGGGAGTGAACCTTACTCATCTATAACTGCGATTTACAATCAGGTTTTGAAAAAGGTCCTCCCATTATATGGTATTAGTT
TATGTGAAGTGAAAAGGAAAAACTATAAAGGACAGCCTATAAGTGCTTCACGTGTAAGGAGGTATCTGGGAGAAGGCAAT
TATAAAAAAGTAAGGGATCTGGTACCAGAGGTAACCTATAAATTTTTACAGAGTCCTGGAGCCCAAAAAATTGTTGATTA
CCTCCAAAATAAGTTCAGGGGGGATAAAAATGGAAATTAA

Upstream 100 bases:

>100_bases
CCAACAGGAACCTGTTTAGCCTTTACAGAAGGAATGGATGTTGTCAAGATCTCTAAAAAGCTTGCTGAATTAATTTAATA
TTTAACCGGGGGTTTTTTCT

Downstream 100 bases:

>100_bases
GAGAACTGCAAGTGCCGGAACAATGGAATCATCAGATATAATGATAACTGTAAAACCGTCAAATAATGGTATAAAAATTG
AACTTAAAAGTGATGTAGAA

Product: (Citrate (pro-3S)-lyase) ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSIWNLRKEILYPPVDDMTEVATFLNGLNLELEERLDCILVLRINNRVVGTGGLDGNILKCVGVDPEFQNQGLLNTIVSE
LKHILYRKGYNSLFVYTPEHQVVRYKNLGFVEIESVGDYPVLMEDSMEGFNGFIRSLKKKTQRINLDLKKIEVASLVMNC
NPFTKGHLYLIEKAARERDIVFIFLLTEDRSLFPANIRYELVKKGTKHLDNVIVFRGGDYILSYTTFPDYFIGSQRGEEK
ARRYAELDARIFARHIAPALNINHRYVGSEPYSSITAIYNQVLKKVLPLYGISLCEVKRKNYKGQPISASRVRRYLGEGN
YKKVRDLVPEVTYKFLQSPGAQKIVDYLQNKFRGDKNGN

Sequences:

>Translated_359_residues
MSIWNLRKEILYPPVDDMTEVATFLNGLNLELEERLDCILVLRINNRVVGTGGLDGNILKCVGVDPEFQNQGLLNTIVSE
LKHILYRKGYNSLFVYTPEHQVVRYKNLGFVEIESVGDYPVLMEDSMEGFNGFIRSLKKKTQRINLDLKKIEVASLVMNC
NPFTKGHLYLIEKAARERDIVFIFLLTEDRSLFPANIRYELVKKGTKHLDNVIVFRGGDYILSYTTFPDYFIGSQRGEEK
ARRYAELDARIFARHIAPALNINHRYVGSEPYSSITAIYNQVLKKVLPLYGISLCEVKRKNYKGQPISASRVRRYLGEGN
YKKVRDLVPEVTYKFLQSPGAQKIVDYLQNKFRGDKNGN
>Mature_358_residues
SIWNLRKEILYPPVDDMTEVATFLNGLNLELEERLDCILVLRINNRVVGTGGLDGNILKCVGVDPEFQNQGLLNTIVSEL
KHILYRKGYNSLFVYTPEHQVVRYKNLGFVEIESVGDYPVLMEDSMEGFNGFIRSLKKKTQRINLDLKKIEVASLVMNCN
PFTKGHLYLIEKAARERDIVFIFLLTEDRSLFPANIRYELVKKGTKHLDNVIVFRGGDYILSYTTFPDYFIGSQRGEEKA
RRYAELDARIFARHIAPALNINHRYVGSEPYSSITAIYNQVLKKVLPLYGISLCEVKRKNYKGQPISASRVRRYLGEGNY
KKVRDLVPEVTYKFLQSPGAQKIVDYLQNKFRGDKNGN

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=326, Percent_Identity=37.4233128834356, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 41294; Mature: 41163

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIWNLRKEILYPPVDDMTEVATFLNGLNLELEERLDCILVLRINNRVVGTGGLDGNILK
CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCEEEEEEECCEEEECCCCCCCEEE
CVGVDPEFQNQGLLNTIVSELKHILYRKGYNSLFVYTPEHQVVRYKNLGFVEIESVGDYP
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEEECCCCCC
VLMEDSMEGFNGFIRSLKKKTQRINLDLKKIEVASLVMNCNPFTKGHLYLIEKAARERDI
EEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHCCCCCE
VFIFLLTEDRSLFPANIRYELVKKGTKHLDNVIVFRGGDYILSYTTFPDYFIGSQRGEEK
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCHHCCCCCCHHH
ARRYAELDARIFARHIAPALNINHRYVGSEPYSSITAIYNQVLKKVLPLYGISLCEVKRK
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NYKGQPISASRVRRYLGEGNYKKVRDLVPEVTYKFLQSPGAQKIVDYLQNKFRGDKNGN
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SIWNLRKEILYPPVDDMTEVATFLNGLNLELEERLDCILVLRINNRVVGTGGLDGNILK
CHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCEEEEEEECCEEEECCCCCCCEEE
CVGVDPEFQNQGLLNTIVSELKHILYRKGYNSLFVYTPEHQVVRYKNLGFVEIESVGDYP
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEEECCCCCC
VLMEDSMEGFNGFIRSLKKKTQRINLDLKKIEVASLVMNCNPFTKGHLYLIEKAARERDI
EEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEHHCCCCCE
VFIFLLTEDRSLFPANIRYELVKKGTKHLDNVIVFRGGDYILSYTTFPDYFIGSQRGEEK
EEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCHHCCCCCCHHH
ARRYAELDARIFARHIAPALNINHRYVGSEPYSSITAIYNQVLKKVLPLYGISLCEVKRK
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NYKGQPISASRVRRYLGEGNYKKVRDLVPEVTYKFLQSPGAQKIVDYLQNKFRGDKNGN
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]