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The map label for this gene is yqkF [H]

Identifier: 220931241

GI number: 220931241

Start: 405278

End: 406216

Strand: Direct

Name: yqkF [H]

Synonym: Hore_03950

Alternate gene names: 220931241

Gene position: 405278-406216 (Clockwise)

Preceding gene: 220931240

Following gene: 220931243

Centisome position: 15.72

GC content: 40.68

Gene sequence:

>939_bases
ATGTTGAAGAAGAGGAAACTGGGAACAACTGGCCTTGAAGTTTCTGAAATTGGTTTTGGATGCTGGCAGCTGGGAAACAC
GAAAGACTGGCGTGGTGCTACCGGTGAAGATGCAATCCGGTTGGTCCATAAGGCTATTGAAATGGGGTGTAATTTTTTTG
ATACAGCTCCCAATTATGCCGGGGGAAAGAGTGAGGAATTACTGGGTAAAGCCCTTAAAGGTAAAAGGGATAAAGTTATT
ATTAGTTCAAAATTTGGGCATACCCCTGATGGTCAGACCAGTTTTGACCCGTCTTTATTGAAAAAATCTGTAGAAGAAAG
TTTGGGAAGGCTAGAGACAGATTATTTAGATATATTGTTACTCCATAGTCCTCCCGTGGAAGTAATAAAGGGGAGTCAGG
GACATTATCAAATTATGGAGGAGCTTAAAAAGGAAGGAAAAATACGTTTCTATGGGGCTTCAGTTGACACCGGTCAGCAA
ATGCTGGATGTTATAAATAACAGCAACTCTAGCGTTATTGAAATTCTTTTTAATCTTTTCCACCAGGAGCCCAGGAGGGT
TTTCCCGAGGGCTGGAGAAGAAGGTGTGGGGTTAATTGTTAAAGTTCCACTGGATTCGGGATGGCTCACCGGTAAGTATA
ATGCCGACAGTACTTTTACAGGAATCAGGGAACGGTGGAGTAGAGAAGTTATTAAACGGAGGGCCTCACTGGTGGAAATG
GTTAAGGACATAAAGGATGATAATACCAGTATGGTTCATGAGGCTTTAAAATATATTCTGGCTTATCCACAGGTATCAAC
AGTCATTCCAGGTGTTAGAACTGAAGAGCACTTAATTGAAAACTTTAAGGCAAGTGAAAGAAAACTATCTGATGATAGAT
TAAGGAAATATGAAGATTTATACAATAAATATATTGAGGGTAATGAGCTGCCCTGGTAA

Upstream 100 bases:

>100_bases
ACAAGAACTGATAAATAAAAAGTTAAAAAATGAACTTAAATATAAATTTAAAAAGCCCGGGCATGATTCAGATAAGGGCT
GTTTTAAAAAGGGGGAAGTT

Downstream 100 bases:

>100_bases
AGTCCCCTACAAAAAAATATATTTATAAATATCGGGTTTTATACAGCTATAAAAAACCTCCAGATTCTTCTGGAGGTTAT
AATTTTTTTCTTGTTATTTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MLKKRKLGTTGLEVSEIGFGCWQLGNTKDWRGATGEDAIRLVHKAIEMGCNFFDTAPNYAGGKSEELLGKALKGKRDKVI
ISSKFGHTPDGQTSFDPSLLKKSVEESLGRLETDYLDILLLHSPPVEVIKGSQGHYQIMEELKKEGKIRFYGASVDTGQQ
MLDVINNSNSSVIEILFNLFHQEPRRVFPRAGEEGVGLIVKVPLDSGWLTGKYNADSTFTGIRERWSREVIKRRASLVEM
VKDIKDDNTSMVHEALKYILAYPQVSTVIPGVRTEEHLIENFKASERKLSDDRLRKYEDLYNKYIEGNELPW

Sequences:

>Translated_312_residues
MLKKRKLGTTGLEVSEIGFGCWQLGNTKDWRGATGEDAIRLVHKAIEMGCNFFDTAPNYAGGKSEELLGKALKGKRDKVI
ISSKFGHTPDGQTSFDPSLLKKSVEESLGRLETDYLDILLLHSPPVEVIKGSQGHYQIMEELKKEGKIRFYGASVDTGQQ
MLDVINNSNSSVIEILFNLFHQEPRRVFPRAGEEGVGLIVKVPLDSGWLTGKYNADSTFTGIRERWSREVIKRRASLVEM
VKDIKDDNTSMVHEALKYILAYPQVSTVIPGVRTEEHLIENFKASERKLSDDRLRKYEDLYNKYIEGNELPW
>Mature_312_residues
MLKKRKLGTTGLEVSEIGFGCWQLGNTKDWRGATGEDAIRLVHKAIEMGCNFFDTAPNYAGGKSEELLGKALKGKRDKVI
ISSKFGHTPDGQTSFDPSLLKKSVEESLGRLETDYLDILLLHSPPVEVIKGSQGHYQIMEELKKEGKIRFYGASVDTGQQ
MLDVINNSNSSVIEILFNLFHQEPRRVFPRAGEEGVGLIVKVPLDSGWLTGKYNADSTFTGIRERWSREVIKRRASLVEM
VKDIKDDNTSMVHEALKYILAYPQVSTVIPGVRTEEHLIENFKASERKLSDDRLRKYEDLYNKYIEGNELPW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=28.2051282051282, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=27.8846153846154, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=28.1553398058252, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI27436971, Length=319, Percent_Identity=26.9592476489028, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=25.2427184466019, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=25.2427184466019, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=27.0516717325228, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=27.0440251572327, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789375, Length=318, Percent_Identity=26.7295597484277, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788081, Length=295, Percent_Identity=24.7457627118644, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082198, Length=144, Percent_Identity=31.9444444444444, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=29.1291291291291, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646159, Length=163, Percent_Identity=34.3558282208589, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35283; Mature: 35283

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKRKLGTTGLEVSEIGFGCWQLGNTKDWRGATGEDAIRLVHKAIEMGCNFFDTAPNYA
CCCCCCCCCCCCCHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCC
GGKSEELLGKALKGKRDKVIISSKFGHTPDGQTSFDPSLLKKSVEESLGRLETDYLDILL
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEE
LHSPPVEVIKGSQGHYQIMEELKKEGKIRFYGASVDTGQQMLDVINNSNSSVIEILFNLF
ECCCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHH
HQEPRRVFPRAGEEGVGLIVKVPLDSGWLTGKYNADSTFTGIRERWSREVIKRRASLVEM
HHCHHHHCCCCCCCCCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKDIKDDNTSMVHEALKYILAYPQVSTVIPGVRTEEHLIENFKASERKLSDDRLRKYEDL
HHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
YNKYIEGNELPW
HHHHCCCCCCCC
>Mature Secondary Structure
MLKKRKLGTTGLEVSEIGFGCWQLGNTKDWRGATGEDAIRLVHKAIEMGCNFFDTAPNYA
CCCCCCCCCCCCCHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCC
GGKSEELLGKALKGKRDKVIISSKFGHTPDGQTSFDPSLLKKSVEESLGRLETDYLDILL
CCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEE
LHSPPVEVIKGSQGHYQIMEELKKEGKIRFYGASVDTGQQMLDVINNSNSSVIEILFNLF
ECCCCHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHH
HQEPRRVFPRAGEEGVGLIVKVPLDSGWLTGKYNADSTFTGIRERWSREVIKRRASLVEM
HHCHHHHCCCCCCCCCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VKDIKDDNTSMVHEALKYILAYPQVSTVIPGVRTEEHLIENFKASERKLSDDRLRKYEDL
HHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH
YNKYIEGNELPW
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]