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The map label for this gene is cysS [H]

Identifier: 220930944

GI number: 220930944

Start: 115070

End: 116524

Strand: Direct

Name: cysS [H]

Synonym: Hore_00960

Alternate gene names: 220930944

Gene position: 115070-116524 (Clockwise)

Preceding gene: 220930943

Following gene: 220930945

Centisome position: 4.46

GC content: 38.83

Gene sequence:

>1455_bases
ATGCTCAGAGTATACAATACTTTAAGTAGAAAAAAGGAGAAGTTTACTCCTCTAGAAACCGGGAAAGTCAGGATGTATGT
CTGTGGTCTAACCGTCCAGAATTACGCCCATATTGGACATATCAGGAGTGCGGTCAATTATGATGTTATCCGACGTTATC
TTGAATATAAAGGGTATGAGGTAACCTATGTTCAGAACTTTACTGATATTAATGAAAAAATAGTGGCCCGGGCCCGGGAA
GAAGGGTTAAGGCCACTGGAACTTGCTGATAAATATACTAAAGCCTATCTTGAAGATATTGAGAAGATGAAGATAAAAAG
GGCAGATGTATACTGCCGGGCTACTGATACTATAAAAGAGATAATAAAAATGGTTAAAAAACTACTCGATAAAGGCTATG
CTTATGAGGTCAATGGTAATGTATACTTCAGTGTGGAAAAATTTAGTGATTACGGAAAATTGTCCGGTCGAAATTTAGAA
GAAATGCAGGCCGGGGCCAGAGTTGAAGTTAATGAAGAAAAGAGACATCCAATGGATTTTGCTTTATGGAAAAAGGCTCC
CGCTGGTGAAATATCCTGGGATAGTCCCTGGGGGAAGGGATGGCCTGGCTGGCATATTGAATGTTCGGCAATGTCTATTA
AATATCTGGGGAAGAGGATAGATATTCATGGTGGTGGCACAGATCTGATATTTCCCCACCATGAGAATGAGATTGCCCAG
TCAGAGTCATGTACCGGGGAGAAACCCTTTGTTAAATACTGGCTTCACAATGGTTCGGTTAATTTAAAAGGTGAGAAAAT
GTCAAAATCTCTGGGTAATTTCTTTACTGTTCGTGAAATTTTAAAGGAGTTTAAACCAGATGAAGTGAGGTACTTCCTTT
TAACCAAACATTATCGCAGTCCCATTGATTTTAATTTTGAGGAAGTAGAAGCTGCCCGTAAAAGCTGGCGGAAACTTGTG
AATACTTACCAGGTGATGGTTCAGATTCTGGAAAAGGGAGTTATTACAAAAAACAAAATAACTGAAAATACTAAAGGTGA
AAACACCATTATAAGTATTTTAAATAAAAAGGAAAAAGAATTTGAAGAGGCTATGGATGATGACTTTAATACAGCCCGGG
CTACAGGGGTAATGCATGAACTTGCCAGAGAAATTAACACATTTGTTAATTCTCCTGAGTTTGAGCTGAATGGAGAAACC
AGTAAAGTACTCAAAAAAGCTCAAAACCTTTTTGACCGCTTTTCTGATATTCTGGGTCTTGATTTGGCATTTTCTTCTTC
TGATGAGGTAGATAATGAAATCTTAAATAACCTGGTTGATTTTATTCTTGAGATCAGGGATGAAGCAAGGCAGGAGAAAA
ACTGGCAGCTGGCTGATAGAATTCGTGATGGGCTTGAAGACCTTGGTTTTGAAATAAAAGATACCCCCCATGGGGTCAGG
TGGGAAAGGAAGTAA

Upstream 100 bases:

>100_bases
TAATTAAATAGATGATATGATTAGATGATATAAGATATATTTATATGGATATCCTGATGGCAGGATTTTTACCTGTTTGA
GTGAAAGGGTGAAGCATAAT

Downstream 100 bases:

>100_bases
AATTATGACCAATAAAGTTAATCTTATGTCTCCAGGCCACCTGGCCTATGTTGGTGATAGTGTTTATGAATTACTGGTCA
GAAATTATCTGGTAAACCAG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MLRVYNTLSRKKEKFTPLETGKVRMYVCGLTVQNYAHIGHIRSAVNYDVIRRYLEYKGYEVTYVQNFTDINEKIVARARE
EGLRPLELADKYTKAYLEDIEKMKIKRADVYCRATDTIKEIIKMVKKLLDKGYAYEVNGNVYFSVEKFSDYGKLSGRNLE
EMQAGARVEVNEEKRHPMDFALWKKAPAGEISWDSPWGKGWPGWHIECSAMSIKYLGKRIDIHGGGTDLIFPHHENEIAQ
SESCTGEKPFVKYWLHNGSVNLKGEKMSKSLGNFFTVREILKEFKPDEVRYFLLTKHYRSPIDFNFEEVEAARKSWRKLV
NTYQVMVQILEKGVITKNKITENTKGENTIISILNKKEKEFEEAMDDDFNTARATGVMHELAREINTFVNSPEFELNGET
SKVLKKAQNLFDRFSDILGLDLAFSSSDEVDNEILNNLVDFILEIRDEARQEKNWQLADRIRDGLEDLGFEIKDTPHGVR
WERK

Sequences:

>Translated_484_residues
MLRVYNTLSRKKEKFTPLETGKVRMYVCGLTVQNYAHIGHIRSAVNYDVIRRYLEYKGYEVTYVQNFTDINEKIVARARE
EGLRPLELADKYTKAYLEDIEKMKIKRADVYCRATDTIKEIIKMVKKLLDKGYAYEVNGNVYFSVEKFSDYGKLSGRNLE
EMQAGARVEVNEEKRHPMDFALWKKAPAGEISWDSPWGKGWPGWHIECSAMSIKYLGKRIDIHGGGTDLIFPHHENEIAQ
SESCTGEKPFVKYWLHNGSVNLKGEKMSKSLGNFFTVREILKEFKPDEVRYFLLTKHYRSPIDFNFEEVEAARKSWRKLV
NTYQVMVQILEKGVITKNKITENTKGENTIISILNKKEKEFEEAMDDDFNTARATGVMHELAREINTFVNSPEFELNGET
SKVLKKAQNLFDRFSDILGLDLAFSSSDEVDNEILNNLVDFILEIRDEARQEKNWQLADRIRDGLEDLGFEIKDTPHGVR
WERK
>Mature_484_residues
MLRVYNTLSRKKEKFTPLETGKVRMYVCGLTVQNYAHIGHIRSAVNYDVIRRYLEYKGYEVTYVQNFTDINEKIVARARE
EGLRPLELADKYTKAYLEDIEKMKIKRADVYCRATDTIKEIIKMVKKLLDKGYAYEVNGNVYFSVEKFSDYGKLSGRNLE
EMQAGARVEVNEEKRHPMDFALWKKAPAGEISWDSPWGKGWPGWHIECSAMSIKYLGKRIDIHGGGTDLIFPHHENEIAQ
SESCTGEKPFVKYWLHNGSVNLKGEKMSKSLGNFFTVREILKEFKPDEVRYFLLTKHYRSPIDFNFEEVEAARKSWRKLV
NTYQVMVQILEKGVITKNKITENTKGENTIISILNKKEKEFEEAMDDDFNTARATGVMHELAREINTFVNSPEFELNGET
SKVLKKAQNLFDRFSDILGLDLAFSSSDEVDNEILNNLVDFILEIRDEARQEKNWQLADRIRDGLEDLGFEIKDTPHGVR
WERK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=501, Percent_Identity=34.1317365269461, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI62240992, Length=407, Percent_Identity=32.6781326781327, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI21269877, Length=407, Percent_Identity=32.6781326781327, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI303304987, Length=407, Percent_Identity=32.6781326781327, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI10835051, Length=407, Percent_Identity=32.6781326781327, Blast_Score=202, Evalue=7e-52,
Organism=Escherichia coli, GI1786737, Length=491, Percent_Identity=43.1771894093686, Blast_Score=388, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17509795, Length=438, Percent_Identity=30.8219178082192, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17509797, Length=438, Percent_Identity=30.8219178082192, Blast_Score=192, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324082, Length=318, Percent_Identity=33.9622641509434, Blast_Score=198, Evalue=2e-51,
Organism=Drosophila melanogaster, GI19922218, Length=505, Percent_Identity=31.8811881188119, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI19922364, Length=415, Percent_Identity=31.566265060241, Blast_Score=200, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56317; Mature: 56317

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVYNTLSRKKEKFTPLETGKVRMYVCGLTVQNYAHIGHIRSAVNYDVIRRYLEYKGYE
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VTYVQNFTDINEKIVARAREEGLRPLELADKYTKAYLEDIEKMKIKRADVYCRATDTIKE
EEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHH
IIKMVKKLLDKGYAYEVNGNVYFSVEKFSDYGKLSGRNLEEMQAGARVEVNEEKRHPMDF
HHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCH
ALWKKAPAGEISWDSPWGKGWPGWHIECSAMSIKYLGKRIDIHGGGTDLIFPHHENEIAQ
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCEEEECCCCCCEECCCCCCHHHH
SESCTGEKPFVKYWLHNGSVNLKGEKMSKSLGNFFTVREILKEFKPDEVRYFLLTKHYRS
CCCCCCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCC
PIDFNFEEVEAARKSWRKLVNTYQVMVQILEKGVITKNKITENTKGENTIISILNKKEKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FEEAMDDDFNTARATGVMHELAREINTFVNSPEFELNGETSKVLKKAQNLFDRFSDILGL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHCC
DLAFSSSDEVDNEILNNLVDFILEIRDEARQEKNWQLADRIRDGLEDLGFEIKDTPHGVR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEECCCCCCCC
WERK
CCCC
>Mature Secondary Structure
MLRVYNTLSRKKEKFTPLETGKVRMYVCGLTVQNYAHIGHIRSAVNYDVIRRYLEYKGYE
CCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VTYVQNFTDINEKIVARAREEGLRPLELADKYTKAYLEDIEKMKIKRADVYCRATDTIKE
EEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHH
IIKMVKKLLDKGYAYEVNGNVYFSVEKFSDYGKLSGRNLEEMQAGARVEVNEEKRHPMDF
HHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCH
ALWKKAPAGEISWDSPWGKGWPGWHIECSAMSIKYLGKRIDIHGGGTDLIFPHHENEIAQ
HHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCEEEECCCCCCEECCCCCCHHHH
SESCTGEKPFVKYWLHNGSVNLKGEKMSKSLGNFFTVREILKEFKPDEVRYFLLTKHYRS
CCCCCCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCC
PIDFNFEEVEAARKSWRKLVNTYQVMVQILEKGVITKNKITENTKGENTIISILNKKEKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FEEAMDDDFNTARATGVMHELAREINTFVNSPEFELNGETSKVLKKAQNLFDRFSDILGL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHCC
DLAFSSSDEVDNEILNNLVDFILEIRDEARQEKNWQLADRIRDGLEDLGFEIKDTPHGVR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEECCCCCCCC
WERK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA