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The map label for this gene is nadA [H]

Identifier: 220930910

GI number: 220930910

Start: 72532

End: 73437

Strand: Direct

Name: nadA [H]

Synonym: Hore_00620

Alternate gene names: 220930910

Gene position: 72532-73437 (Clockwise)

Preceding gene: 220930909

Following gene: 220930911

Centisome position: 2.81

GC content: 41.39

Gene sequence:

>906_bases
ATGGGAAAAGAGGTTATTGAGAGGATAAAAGAATTAAAAAAAGAACGTAATGCCGTCATCCTGGCCCATAATTATCAAAT
TGGTGAAGTACAGGATGTAGCTGATTTTGTTGGAGATTCCTTTGGGTTAAGTCGTAAGGCTGCTGAAACAGATGCAGATG
TCATTGTGTTCTGTGGGGTTAAATTTATGGCCGAGAGTGCTAAAATACTGTCTCCTGAAAAGACTGTTCTTTTACCGGAA
AAAGAGGCAGGCTGTCCTCTGGCCAGTATGGTAGATGTGGATGGTCTTAAGGAAATGAAGAAGAAATACCCCGGGGCAAC
CGTAGTTACTTATGTGAATTCAACGGCTGCTGTTAAGGCTGAAAGTGATATATGCTGTACTTCTTCAAATGCCCTTAAAG
TTGTTGAGTCAGTACCAGGGAATCAGGTTTTATTTGTACCAGATAAAAATCTGGGCCAGTATGTAGCCCGCCGTACCAGT
AAAGAAGTTATCATCTGGGATGGCTACTGTACTACCCACCATCGTGTTGATCCAGAGGAGGTAAAAGAGGTTAAAGCAGC
CCATCCGGACGCCCCGATAGTAGTTCACCCTGAATGTCCCCCTGAAGTGGTGGAACTGGCTGATCATGTTGATAGTACTG
CCGGAATATTAAAATACTGTCGCGAGAGTGAAGCTGATACCATAATTGTTGGTACCGAGCAGGGACTAATCCATAGACTT
AATAAGGAAAACCCTGATAAAAAGTTTTTTGTCTTAAGCCCTAAGTTGATATGTCCCAATATGAAAAAAACTAATCTTGA
TAAAGTACTTAAGTCACTGGAAAAAATGGAAACAAGGGTAGAAATACCGGAAAACATAAGAACCAGGGCCTATAATGCCT
TGAAAAAAATGCTGGAGGTCAAATAA

Upstream 100 bases:

>100_bases
TGGTATTATTAATAAAGATATATAATGTAATTACTGTTTTTTTAAAATGATAAATTCCGGGTTATATTGTGATGAATGTA
TCCAGATGGGAGGGTATAAC

Downstream 100 bases:

>100_bases
CCTCACTAAATGACGGTAGGGTGGATAAACATGGGAGATATAAAATATAAAACTACAGATTTTGTTATAATCGGGACTGG
AATAGCTGGTCTGTATACTG

Product: quinolinate synthetase complex subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MGKEVIERIKELKKERNAVILAHNYQIGEVQDVADFVGDSFGLSRKAAETDADVIVFCGVKFMAESAKILSPEKTVLLPE
KEAGCPLASMVDVDGLKEMKKKYPGATVVTYVNSTAAVKAESDICCTSSNALKVVESVPGNQVLFVPDKNLGQYVARRTS
KEVIIWDGYCTTHHRVDPEEVKEVKAAHPDAPIVVHPECPPEVVELADHVDSTAGILKYCRESEADTIIVGTEQGLIHRL
NKENPDKKFFVLSPKLICPNMKKTNLDKVLKSLEKMETRVEIPENIRTRAYNALKKMLEVK

Sequences:

>Translated_301_residues
MGKEVIERIKELKKERNAVILAHNYQIGEVQDVADFVGDSFGLSRKAAETDADVIVFCGVKFMAESAKILSPEKTVLLPE
KEAGCPLASMVDVDGLKEMKKKYPGATVVTYVNSTAAVKAESDICCTSSNALKVVESVPGNQVLFVPDKNLGQYVARRTS
KEVIIWDGYCTTHHRVDPEEVKEVKAAHPDAPIVVHPECPPEVVELADHVDSTAGILKYCRESEADTIIVGTEQGLIHRL
NKENPDKKFFVLSPKLICPNMKKTNLDKVLKSLEKMETRVEIPENIRTRAYNALKKMLEVK
>Mature_300_residues
GKEVIERIKELKKERNAVILAHNYQIGEVQDVADFVGDSFGLSRKAAETDADVIVFCGVKFMAESAKILSPEKTVLLPEK
EAGCPLASMVDVDGLKEMKKKYPGATVVTYVNSTAAVKAESDICCTSSNALKVVESVPGNQVLFVPDKNLGQYVARRTSK
EVIIWDGYCTTHHRVDPEEVKEVKAAHPDAPIVVHPECPPEVVELADHVDSTAGILKYCRESEADTIIVGTEQGLIHRLN
KENPDKKFFVLSPKLICPNMKKTNLDKVLKSLEKMETRVEIPENIRTRAYNALKKMLEVK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=34.5161290322581, Blast_Score=194, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 33375; Mature: 33244

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKEVIERIKELKKERNAVILAHNYQIGEVQDVADFVGDSFGLSRKAAETDADVIVFCGV
CCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECH
KFMAESAKILSPEKTVLLPEKEAGCPLASMVDVDGLKEMKKKYPGATVVTYVNSTAAVKA
HHHHCCHHHCCCCCEEEECCCCCCCCHHHHHCHHHHHHHHHHCCCCEEEEEECCCEEEEC
ESDICCTSSNALKVVESVPGNQVLFVPDKNLGQYVARRTSKEVIIWDGYCTTHHRVDPEE
CCCEEECCCCHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEEECCEECCCCCCCHHH
VKEVKAAHPDAPIVVHPECPPEVVELADHVDSTAGILKYCRESEADTIIVGTEQGLIHRL
HHHHHHCCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCHHHHHHH
NKENPDKKFFVLSPKLICPNMKKTNLDKVLKSLEKMETRVEIPENIRTRAYNALKKMLEV
CCCCCCCEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
GKEVIERIKELKKERNAVILAHNYQIGEVQDVADFVGDSFGLSRKAAETDADVIVFCGV
CHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECH
KFMAESAKILSPEKTVLLPEKEAGCPLASMVDVDGLKEMKKKYPGATVVTYVNSTAAVKA
HHHHCCHHHCCCCCEEEECCCCCCCCHHHHHCHHHHHHHHHHCCCCEEEEEECCCEEEEC
ESDICCTSSNALKVVESVPGNQVLFVPDKNLGQYVARRTSKEVIIWDGYCTTHHRVDPEE
CCCEEECCCCHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEEECCEECCCCCCCHHH
VKEVKAAHPDAPIVVHPECPPEVVELADHVDSTAGILKYCRESEADTIIVGTEQGLIHRL
HHHHHHCCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCHHHHHHH
NKENPDKKFFVLSPKLICPNMKKTNLDKVLKSLEKMETRVEIPENIRTRAYNALKKMLEV
CCCCCCCEEEEECCCEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA