BacMap

Definition	Halothermothrix orenii H 168 chromosome, complete genome.
Accession	NC_011899
Length	2,578,146

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The map label for this gene is ftsH

Identifier: 220930906

GI number: 220930906

Start: 66050

End: 67942

Strand: Direct

Name: ftsH

Synonym: Hore_00580

Alternate gene names: 220930906

Gene position: 66050-67942 (Clockwise)

Preceding gene: 220930905

Following gene: 220930907

Centisome position: 2.56

GC content: 42.68

Gene sequence:

>1893_bases
TTGAACAACTTTATGAAAAATATAGGATTCTATTTAGTACTCATTGCCCTCTCAATATTGGTTGCCCAATTTTTTGTTGA
TACAGATGTAAACACTATTGTTGATACAGATGTAAACACTATTAAGGATTTTACCTATAGTGATTTAATTAATTATGTGG
AACAGGGAAAAATAAATGAGGTAACTATTATTGGTAATGAAGCCGTTAAAGGTACCTATAATCATAGAGAGTTTAATGTA
CCTATACCGCCAGAAGCAGTACCGGATTTGATGGCTGAACTGAGAGAGGCTGATGTTGAAATTAAAACAGAACCCGAACC
GACTGCCCCCTGGTGGACGGGCATGTTGGCGTATATCTTACCGATTATATTATTGATCGGAGCCTGGTTTTTTATAATGC
AGCGTATGCAGGGTGGCGGTAGTCAGATGATGTCCTTCGGGAAAAGCCGCGCCCGACTCAGTGAAAATGGAAAAAAAGTT
ACTTTTGAGGATGTTGCTAATTATGAAGAGGTTAAAGAGGAATTACAGGAAGTTGTCGAGTTTTTAAAAAATCCAGATAA
ATTTACCAGAATGGGGGCCAAAGTCCCCAAAGGAGTCCTTCTGGTAGGACCTCCTGGAACTGGTAAGACCTTGTTGGCCA
GGGCTGTGGCTGGTGAGGCCGGTGTTCCATTCTTTATAATCAGTGGTTCTGATTTTGTTGAAATGTTTGTCGGGGTCGGT
GCCTCACGTGTCAGGGATTTATTTGAACAGGGCAAAAAGAATGCTCCCTGTATTATATTTATTGATGAGCTGGACGCCGT
GGGGCGGCAACGTGGTGCTGGCCTCGGTGGTGGCCATGATGAACGTGAGCAGACCTTAAACCAGCTGCTTGTAGAGATGG
ATGGTTTTGAGCCCAATGAAGGTATTATTGTTATGGCAGCCACAAACCGACCTGATGTTCTTGATCCGGCCCTGCTTAGG
CCTGGTCGTTTTGACCGTCAGGTTGTTGTTGATAAACCGGATGTTAAGGGTAGAATGGGAATCTTAAAGATTCATCTACG
GAATAAACCGGTTGCTGACGATGTTGATGTTGAAGTACTGGCTAAAAGAACCCCTGGTTTTACCGGGGCTGATATGGAAA
ATCTGGCCAATGAGGCTGCTATTCTGGCTGTAAGGCGGCGTAAAAACAAAATAACAATGGAAGACTTTGATGATGCCATA
GATAAAGTAATTGCCGGACCGGCCAAGAAGAGTAAAGTCATGTCAGAAAGGGAACGTAAACTTGTAGCCTATCATGAAAC
CGGGCATGCTTTGGTTGGTGATCTTCTGGAACATGCCGACAGAACCCATAAAATATCAATAGTTCCCCGGGGCCGGGCCG
GAGGAATGAGATGGGCCCTTCCTAAAGAGGATAAAAACTTTATGTCTAAACAGGAATTGTTAGACCAGATAACGGTTTTA
CTTGGAGGTAGGGCTTCTGAATCAATCTTCCTTGAAGATATTAGTACCGGAGCCCAGAATGACCTGGAACGGGCTACTAA
ACTGGCCCGGGCCATGGTAACTGAATATGGTATGAGTGAAAAACTTGGACCTCTAACCCTGGGTCATAAGCACGATGAGC
AGATTTTCCTGGGAAGGGATATATCCCGACAGAGAAATTACAGTGAGGAAATTGCAGCTGAAATTGATAAAGAAGTGAGT
TCTATCATAGAATACTGTTATCAGCGAGCTGAAAAGATTCTTCAGGAAAATACAGCCAAGGTTGAGAGGATTGTCAGGGA
ATTATTAGATAGAGAAACCCTTGATGCCGAACAACTCCAGAAACTCATTAAGGGAGAACCCCTTGATGATGATAGTATTG
ATAATTCTACAGATGAAAATGAAAACAGAGAACATGAAAATAATGACAAATAA

Upstream 100 bases:

>100_bases
TGTATAGTAAAATTGCCAGTATTGTCAAATTAATTCTCTTATGATATAATTATAAATTGTTGTAATGAGATAGTTTACCT
TGAGGGGAGGTTAACCTGTT

Downstream 100 bases:

>100_bases
TAGATTTTAATAAAATAGTGTTATTACTTCAAAATTAGTCACTTTATTAATGCCAGCTTCATGCTGGCATTTTTTATTTC
CAGGAAATTATGTACAAGTT

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MNNFMKNIGFYLVLIALSILVAQFFVDTDVNTIVDTDVNTIKDFTYSDLINYVEQGKINEVTIIGNEAVKGTYNHREFNV
PIPPEAVPDLMAELREADVEIKTEPEPTAPWWTGMLAYILPIILLIGAWFFIMQRMQGGGSQMMSFGKSRARLSENGKKV
TFEDVANYEEVKEELQEVVEFLKNPDKFTRMGAKVPKGVLLVGPPGTGKTLLARAVAGEAGVPFFIISGSDFVEMFVGVG
ASRVRDLFEQGKKNAPCIIFIDELDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFEPNEGIIVMAATNRPDVLDPALLR
PGRFDRQVVVDKPDVKGRMGILKIHLRNKPVADDVDVEVLAKRTPGFTGADMENLANEAAILAVRRRKNKITMEDFDDAI
DKVIAGPAKKSKVMSERERKLVAYHETGHALVGDLLEHADRTHKISIVPRGRAGGMRWALPKEDKNFMSKQELLDQITVL
LGGRASESIFLEDISTGAQNDLERATKLARAMVTEYGMSEKLGPLTLGHKHDEQIFLGRDISRQRNYSEEIAAEIDKEVS
SIIEYCYQRAEKILQENTAKVERIVRELLDRETLDAEQLQKLIKGEPLDDDSIDNSTDENENREHENNDK

Sequences:

>Translated_630_residues
MNNFMKNIGFYLVLIALSILVAQFFVDTDVNTIVDTDVNTIKDFTYSDLINYVEQGKINEVTIIGNEAVKGTYNHREFNV
PIPPEAVPDLMAELREADVEIKTEPEPTAPWWTGMLAYILPIILLIGAWFFIMQRMQGGGSQMMSFGKSRARLSENGKKV
TFEDVANYEEVKEELQEVVEFLKNPDKFTRMGAKVPKGVLLVGPPGTGKTLLARAVAGEAGVPFFIISGSDFVEMFVGVG
ASRVRDLFEQGKKNAPCIIFIDELDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFEPNEGIIVMAATNRPDVLDPALLR
PGRFDRQVVVDKPDVKGRMGILKIHLRNKPVADDVDVEVLAKRTPGFTGADMENLANEAAILAVRRRKNKITMEDFDDAI
DKVIAGPAKKSKVMSERERKLVAYHETGHALVGDLLEHADRTHKISIVPRGRAGGMRWALPKEDKNFMSKQELLDQITVL
LGGRASESIFLEDISTGAQNDLERATKLARAMVTEYGMSEKLGPLTLGHKHDEQIFLGRDISRQRNYSEEIAAEIDKEVS
SIIEYCYQRAEKILQENTAKVERIVRELLDRETLDAEQLQKLIKGEPLDDDSIDNSTDENENREHENNDK
>Mature_630_residues
MNNFMKNIGFYLVLIALSILVAQFFVDTDVNTIVDTDVNTIKDFTYSDLINYVEQGKINEVTIIGNEAVKGTYNHREFNV
PIPPEAVPDLMAELREADVEIKTEPEPTAPWWTGMLAYILPIILLIGAWFFIMQRMQGGGSQMMSFGKSRARLSENGKKV
TFEDVANYEEVKEELQEVVEFLKNPDKFTRMGAKVPKGVLLVGPPGTGKTLLARAVAGEAGVPFFIISGSDFVEMFVGVG
ASRVRDLFEQGKKNAPCIIFIDELDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFEPNEGIIVMAATNRPDVLDPALLR
PGRFDRQVVVDKPDVKGRMGILKIHLRNKPVADDVDVEVLAKRTPGFTGADMENLANEAAILAVRRRKNKITMEDFDDAI
DKVIAGPAKKSKVMSERERKLVAYHETGHALVGDLLEHADRTHKISIVPRGRAGGMRWALPKEDKNFMSKQELLDQITVL
LGGRASESIFLEDISTGAQNDLERATKLARAMVTEYGMSEKLGPLTLGHKHDEQIFLGRDISRQRNYSEEIAAEIDKEVS
SIIEYCYQRAEKILQENTAKVERIVRELLDRETLDAEQLQKLIKGEPLDDDSIDNSTDENENREHENNDK

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=598, Percent_Identity=42.3076923076923, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI7657689, Length=454, Percent_Identity=48.0176211453744, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI21327685, Length=454, Percent_Identity=48.0176211453744, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI4507173, Length=509, Percent_Identity=41.6502946954813, Blast_Score=406, Evalue=1e-113,
Organism=Homo sapiens, GI4506209, Length=258, Percent_Identity=46.1240310077519, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=46.0176991150442, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI24497435, Length=252, Percent_Identity=43.2539682539683, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI45643123, Length=309, Percent_Identity=38.8349514563107, Blast_Score=209, Evalue=9e-54,
Organism=Homo sapiens, GI195539395, Length=260, Percent_Identity=41.5384615384615, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI45643125, Length=309, Percent_Identity=38.1877022653722, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI21361144, Length=237, Percent_Identity=45.5696202531646, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI24430151, Length=251, Percent_Identity=40.2390438247012, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI157671927, Length=247, Percent_Identity=41.7004048582996, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI89064750, Length=252, Percent_Identity=38.8888888888889, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI5729991, Length=252, Percent_Identity=38.8888888888889, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI24430155, Length=252, Percent_Identity=38.8888888888889, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI229577436, Length=248, Percent_Identity=41.5322580645161, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI40806173, Length=201, Percent_Identity=47.2636815920398, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI4505725, Length=225, Percent_Identity=38.2222222222222, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI153792536, Length=297, Percent_Identity=36.3636363636364, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI24497618, Length=279, Percent_Identity=37.6344086021505, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI14149767, Length=246, Percent_Identity=38.6178861788618, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI62177112, Length=246, Percent_Identity=38.6178861788618, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI5901990, Length=270, Percent_Identity=37.7777777777778, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI194018488, Length=296, Percent_Identity=36.1486486486487, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI226371754, Length=236, Percent_Identity=37.7118644067797, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI11875211, Length=267, Percent_Identity=36.3295880149813, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI40806170, Length=267, Percent_Identity=36.3295880149813, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI31742536, Length=235, Percent_Identity=34.468085106383, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI112789543, Length=235, Percent_Identity=34.468085106383, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI31377644, Length=246, Percent_Identity=36.1788617886179, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI156564401, Length=229, Percent_Identity=39.7379912663755, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI7019569, Length=265, Percent_Identity=34.3396226415094, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI17865802, Length=237, Percent_Identity=38.3966244725738, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI310125280, Length=229, Percent_Identity=39.3013100436681, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI310125282, Length=229, Percent_Identity=39.3013100436681, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI64084766, Length=265, Percent_Identity=27.5471698113208, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI116292174, Length=268, Percent_Identity=27.9850746268657, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1789568, Length=602, Percent_Identity=51.4950166112957, Blast_Score=598, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI71994521, Length=456, Percent_Identity=49.780701754386, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI115534323, Length=477, Percent_Identity=44.8637316561845, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17554264, Length=461, Percent_Identity=43.6008676789588, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17563248, Length=258, Percent_Identity=46.1240310077519, Blast_Score=225, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17554786, Length=252, Percent_Identity=44.8412698412698, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI25144278, Length=252, Percent_Identity=44.4444444444444, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=252, Percent_Identity=44.4444444444444, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17508701, Length=237, Percent_Identity=46.4135021097046, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17532375, Length=227, Percent_Identity=40.9691629955947, Blast_Score=208, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI71987364, Length=257, Percent_Identity=42.0233463035019, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71987372, Length=257, Percent_Identity=42.0233463035019, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17563250, Length=251, Percent_Identity=40.2390438247012, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17531535, Length=248, Percent_Identity=43.1451612903226, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=251, Percent_Identity=41.4342629482072, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17508053, Length=250, Percent_Identity=39.2, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17537217, Length=235, Percent_Identity=39.5744680851064, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17554784, Length=246, Percent_Identity=37.8048780487805, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25153574, Length=228, Percent_Identity=39.9122807017544, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI193206114, Length=244, Percent_Identity=39.344262295082, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI133931034, Length=244, Percent_Identity=39.344262295082, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=244, Percent_Identity=39.344262295082, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193209502, Length=227, Percent_Identity=39.647577092511, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17570397, Length=184, Percent_Identity=46.7391304347826, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI32566590, Length=184, Percent_Identity=46.7391304347826, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI133901662, Length=216, Percent_Identity=40.7407407407407, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI133901658, Length=216, Percent_Identity=40.7407407407407, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI86561515, Length=256, Percent_Identity=35.546875, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17508421, Length=236, Percent_Identity=38.5593220338983, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17562804, Length=233, Percent_Identity=36.480686695279, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32563584, Length=232, Percent_Identity=38.7931034482759, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25146157, Length=276, Percent_Identity=35.8695652173913, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17560432, Length=244, Percent_Identity=36.4754098360656, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17541226, Length=259, Percent_Identity=32.4324324324324, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17541224, Length=259, Percent_Identity=32.4324324324324, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71990294, Length=197, Percent_Identity=28.4263959390863, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323736, Length=507, Percent_Identity=46.1538461538462, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6320854, Length=543, Percent_Identity=44.3830570902394, Blast_Score=450, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6325281, Length=452, Percent_Identity=44.9115044247788, Blast_Score=400, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322704, Length=253, Percent_Identity=45.8498023715415, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=42.8571428571429, Blast_Score=214, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=44.7154471544715, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320077, Length=227, Percent_Identity=43.1718061674009, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324691, Length=256, Percent_Identity=43.359375, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320197, Length=307, Percent_Identity=35.5048859934853, Blast_Score=203, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6323429, Length=243, Percent_Identity=39.917695473251, Blast_Score=176, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6322994, Length=233, Percent_Identity=37.7682403433476, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320602, Length=250, Percent_Identity=39.2, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321709, Length=258, Percent_Identity=37.984496124031, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324000, Length=232, Percent_Identity=40.0862068965517, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=240, Percent_Identity=35.4166666666667, Blast_Score=163, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6319554, Length=316, Percent_Identity=32.9113924050633, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325431, Length=252, Percent_Identity=37.3015873015873, Blast_Score=143, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6325183, Length=255, Percent_Identity=34.9019607843137, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321465, Length=229, Percent_Identity=33.1877729257642, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=258, Percent_Identity=34.1085271317829, Blast_Score=120, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6320583, Length=190, Percent_Identity=31.0526315789474, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24665814, Length=513, Percent_Identity=46.0038986354776, Blast_Score=450, Evalue=1e-126,
Organism=Drosophila melanogaster, GI28574878, Length=513, Percent_Identity=46.0038986354776, Blast_Score=450, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24639391, Length=461, Percent_Identity=45.3362255965293, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24658770, Length=446, Percent_Identity=46.1883408071749, Blast_Score=387, Evalue=1e-107,
Organism=Drosophila melanogaster, GI17137738, Length=258, Percent_Identity=46.5116279069767, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI161076486, Length=249, Percent_Identity=40.9638554216867, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI17137560, Length=249, Percent_Identity=40.9638554216867, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI19920408, Length=252, Percent_Identity=43.2539682539683, Blast_Score=216, Evalue=5e-56,
Organism=Drosophila melanogaster, GI161076488, Length=249, Percent_Identity=40.9638554216867, Blast_Score=215, Evalue=6e-56,
Organism=Drosophila melanogaster, GI45554047, Length=170, Percent_Identity=58.2352941176471, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24651451, Length=252, Percent_Identity=43.2539682539683, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI17738151, Length=237, Percent_Identity=45.9915611814346, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24660075, Length=234, Percent_Identity=43.5897435897436, Blast_Score=205, Evalue=9e-53,
Organism=Drosophila melanogaster, GI281365776, Length=234, Percent_Identity=43.5897435897436, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI45552965, Length=234, Percent_Identity=43.5897435897436, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24640100, Length=260, Percent_Identity=40.7692307692308, Blast_Score=202, Evalue=8e-52,
Organism=Drosophila melanogaster, GI24649446, Length=251, Percent_Identity=40.2390438247012, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24663015, Length=250, Percent_Identity=41.2, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI19921202, Length=249, Percent_Identity=39.7590361445783, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24652279, Length=211, Percent_Identity=41.2322274881517, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24656820, Length=248, Percent_Identity=40.7258064516129, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24656825, Length=248, Percent_Identity=40.7258064516129, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281361487, Length=239, Percent_Identity=39.3305439330544, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI18860063, Length=239, Percent_Identity=38.9121338912134, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281363136, Length=236, Percent_Identity=38.135593220339, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI78707192, Length=236, Percent_Identity=38.135593220339, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24644145, Length=242, Percent_Identity=39.2561983471074, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355121, Length=224, Percent_Identity=35.7142857142857, Blast_Score=145, Evalue=9e-35,
Organism=Drosophila melanogaster, GI18859657, Length=233, Percent_Identity=39.0557939914163, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360136, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24644411, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360144, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360140, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360142, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21357333, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281360146, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281360138, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24581396, Length=293, Percent_Identity=35.8361774744027, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28571849, Length=275, Percent_Identity=37.0909090909091, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28571847, Length=275, Percent_Identity=37.0909090909091, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI20129423, Length=255, Percent_Identity=34.5098039215686, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI17864540, Length=219, Percent_Identity=40.6392694063927, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28573010, Length=249, Percent_Identity=37.7510040160643, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI20129529, Length=231, Percent_Identity=33.7662337662338, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24639486, Length=233, Percent_Identity=31.3304721030043, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_HALOH (B8D065)

Other databases:

- EMBL:   CP001098
- RefSeq:   YP_002507814.1
- ProteinModelPortal:   B8D065
- SMR:   B8D065
- MEROPS:   M41.021
- GeneID:   7314276
- GenomeReviews:   CP001098_GR
- KEGG:   hor:Hore_00580
- HOGENOM:   HBG724153
- OMA:   DLMNRRE
- ProtClustDB:   CLSK2806145
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 70411; Mature: 70411

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 426-426

Signals:

None

Transmembrane regions:

HASH(0x1d3e6434)-; HASH(0x261253bc)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFMKNIGFYLVLIALSILVAQFFVDTDVNTIVDTDVNTIKDFTYSDLINYVEQGKINE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCE
VTIIGNEAVKGTYNHREFNVPIPPEAVPDLMAELREADVEIKTEPEPTAPWWTGMLAYIL
EEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHH
PIILLIGAWFFIMQRMQGGGSQMMSFGKSRARLSENGKKVTFEDVANYEEVKEELQEVVE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCHHHHHHHHHHHHH
FLKNPDKFTRMGAKVPKGVLLVGPPGTGKTLLARAVAGEAGVPFFIISGSDFVEMFVGVG
HHHCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCC
ASRVRDLFEQGKKNAPCIIFIDELDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFEPNE
HHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
GIIVMAATNRPDVLDPALLRPGRFDRQVVVDKPDVKGRMGILKIHLRNKPVADDVDVEVL
CEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHH
AKRTPGFTGADMENLANEAAILAVRRRKNKITMEDFDDAIDKVIAGPAKKSKVMSERERK
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVAYHETGHALVGDLLEHADRTHKISIVPRGRAGGMRWALPKEDKNFMSKQELLDQITVL
EEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGGRASESIFLEDISTGAQNDLERATKLARAMVTEYGMSEKLGPLTLGHKHDEQIFLGRD
HCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCC
ISRQRNYSEEIAAEIDKEVSSIIEYCYQRAEKILQENTAKVERIVRELLDRETLDAEQLQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLIKGEPLDDDSIDNSTDENENREHENNDK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MNNFMKNIGFYLVLIALSILVAQFFVDTDVNTIVDTDVNTIKDFTYSDLINYVEQGKINE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCE
VTIIGNEAVKGTYNHREFNVPIPPEAVPDLMAELREADVEIKTEPEPTAPWWTGMLAYIL
EEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHH
PIILLIGAWFFIMQRMQGGGSQMMSFGKSRARLSENGKKVTFEDVANYEEVKEELQEVVE
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCHHHHHHHHHHHHH
FLKNPDKFTRMGAKVPKGVLLVGPPGTGKTLLARAVAGEAGVPFFIISGSDFVEMFVGVG
HHHCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCC
ASRVRDLFEQGKKNAPCIIFIDELDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFEPNE
HHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
GIIVMAATNRPDVLDPALLRPGRFDRQVVVDKPDVKGRMGILKIHLRNKPVADDVDVEVL
CEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHH
AKRTPGFTGADMENLANEAAILAVRRRKNKITMEDFDDAIDKVIAGPAKKSKVMSERERK
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVAYHETGHALVGDLLEHADRTHKISIVPRGRAGGMRWALPKEDKNFMSKQELLDQITVL
EEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LGGRASESIFLEDISTGAQNDLERATKLARAMVTEYGMSEKLGPLTLGHKHDEQIFLGRD
HCCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCC
ISRQRNYSEEIAAEIDKEVSSIIEYCYQRAEKILQENTAKVERIVRELLDRETLDAEQLQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KLIKGEPLDDDSIDNSTDENENREHENNDK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA